The transcriptional regulator Zfat is essential for maintenance and differentiation of the adipocytes.
Ishikura S; Nagai M; Tsunoda T; Nishi K; Tanaka Y; Koyanagi M; Shirasawa S
J. Cell Biochem., 2021年, 122(6):626 - 638, 査読有り

Zfat is indispensable for the development of erythroid cells in the fetal liver.
Doi K; Tsunoda T; Koyanagi M; Tanaka Y; Yamano S; Fujikane A; Nishi K; Ishikura S; Shirasawa S
Anticancer Res., 2019年, 39(8):4495 - 4502, 査読有り

Zfat expression in ZsGreen reporter gene knock-in mice: Implications for a novel function of Zfat in definitive erythropoiesis.
Tsunoda T; Doi K; Ishikura S; Luo H; Nishi K; Matsuzaki H; Koyanagi M; Tanaka Y; Okamura T; Shirasawa S
Int. J. Mol. Med., 2018年, 42(5):2595 - 2603, 査読有り

Molecular mechanisms of transcriptional regulation by the nuclear zinc-finger protein Zfat in T cells
Shuhei Ishikura; Toshiyuki Tsunoda; Kazuhiko Nakabayashi; Keiko Doi; Midori Koyanagi; Keiko Hayashi; Tomoko Kawai; Yoko Tanaka; Yuri Iwaihara; Hao Luo; Kensuke Nishi; Tadashi Okamura; Senji Shirasawa
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 2016年11月, 1859(11):1398 - 1410, 査読有り

The Nuclear Zinc Finger Protein Zfat Maintains Fox01 Protein Levels in Peripheral T Cells by Regulating the Activities of Autophagy and the Akt Signaling Pathway
Shuhei Ishikura; Yuri Iwaihara; Yoko Tanaka; Hao Luo; Kensuke Nishi; Keiko Doi; Midori Koyanagi; Tadashi Okamura; Toshiyuki Tsunoda; Senji Shirasawa
JOURNAL OF BIOLOGICAL CHEMISTRY, 2016年07月, 291(29):15282 - 15291, 査読有り

Zfat-deficient CD4+ CD8+ double-positive thymocytes are susceptible to apoptosis with deregulated activation of p38 and JNK.
Ishikura S; Ogawa M; Doi K; Matsuzaki H; Iwaihara Y; Tanaka Y; Tsunoda T; Hideshima H; Okamura T; Shirasawa S
J. Cell Biochem., 2015年, 116(1):149 - 157, 査読有り

Zfat-Deficiency Results in a Loss of CD3ζ Phosphorylation with Dysregulation of ERK and Egr Activities Leading to Impaired Positive Selection
Masahiro Ogawa; Tadashi Okamura; Shuhei Ishikura; Keiko Doi; Hiroshi Matsuzaki; Yoko Tanaka; Takeharu Ota; Kunihiro Hayakawa; Harumi Suzuki; Toshiyuki Tsunoda; Takehiko Sasazuki; Senji Shirasawa
PLoS ONE, 2013年10月03日, 8(10):e76254, 査読有り

ZFAT plays critical roles in peripheral T cell homeostasis and its T cell receptor-mediated response
Keiko Doi; Takahiro Fujimoto; Tadashi Okamura; Masahiro Ogawa; Yoko Tanaka; Yasumasa Mototani; Motohito Goto; Takeharu Ota; Hiroshi Matsuzaki; Masahide Kuroki; Toshiyuki Tsunoda; Takehiko Sasazuki; Senji Shirasawa
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2012年08月, 425(1):107 - 112, 査読有り

Inhibition of Phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model
Toshiyuki Tsunoda; Takeharu Ota; Takahiro Fujimoto; Keiko Doi; Yoko Tanaka; Yasuhiro Yoshida; Masahiro Ogawa; Hiroshi Matsuzaki; Masato Hamabashiri; Darren R. Tyson; Masahide Kuroki; Shingo Miyamoto; Senji Shirasawa
MOLECULAR CANCER, 2012年07月, 11(1):46, 査読有り

KRAS Up-regulates the Expression of miR-181a, miR-200c and miR-210 in a Three-dimensional-specific Manner in DLD-1 Colorectal Cancer Cells
Takeharu Ota; Keiko Doi; Takahiro Fujimoto; Yoko Tanaka; Masahiro Ogawa; Hiroshi Matsuzaki; Masahide Kuroki; Shingo Miyamoto; Senji Shirasawa; Toshiyuki Tsunoda
ANTICANCER RESEARCH, 2012年06月, 32(6):2271 - 2275, 査読有り

ALPK2 is Crucial for Luminal Apoptosis and DNA Repair-related Gene Expression in a Three-dimensional Colonic-crypt Model
Yasuhiro Yoshida; Toshiyuki Tsunoda; Keiko Doi; Takahiro Fujimoto; Yoko Tanaka; Takeharu Ota; Masahiro Ogawa; Hiroshi Matsuzaki; Masahide Kuroki; Akinori Iwasaki; Senji Shirasawa
ANTICANCER RESEARCH, 2012年06月, 32(6):2301 - 2308, 査読有り

Oncogenic KRAS Regulates miR-200c and miR-221/222 in a 3D-Specific Manner in Colorectal Cancer Cells
Toshiyuki Tsunoda; Yasuo Takashima; Yasuhiro Yoshida; Keiko Doi; Yoko Tanaka; Takahiro Fujimoto; Takashi Machida; Takeharu Ota; Midori Koyanagi; Masahide Kuroki; Takehiko Sasazuki; Senji Shirasawa
ANTICANCER RESEARCH, 2011年07月, 31(7):2453 - 2459, 査読有り

KRAS-mediated Up-regulation of RRM2 Expression Is Essential for the Proliferation of Colorectal Cancer Cell Lines
Yasuhiro Yoshida; Toshiyuki Tsunoda; Keiko Doi; Yoko Tanaka; Takahiro Fujimoto; Takashi Machida; Takeharu Ota; Midori Koyanagi; Yasuo Takashima; Takehiko Sasazuki; Masahide Kuroki; Akinori Iwasaki; Senji Shirasawa
ANTICANCER RESEARCH, 2011年07月, 31(7):2535 - 2539, 査読有り

KRAS-induced actin-interacting protein is required for the proper localization of inositol 1,4,5-trisphosphate receptor in the epithelial cells
Takahiro Fujimoto; Takashi Machida; Yoko Tanaka; Toshiyuki Tsunoda; Keiko Doi; Takeharu Ota; Tadashi Okamura; Masahide Kuroki; Senji Shirasawa
Biochemical and Biophysical Research Communications, 2011年04月08日, 407(2):438 - 443, 査読有り

ZFAT IS A CRITICAL MOLECULE FOR CELL SURVIVAL IN MOUSE EMBRYONIC FIBROBLASTS
Keiko Doi; Takahiro Fujimoto; Midori Koyanagi; Toshiyuki Tsunoda; Yoko Tanaka; Yasuhiro Yoshida; Yasuo Takashima; Masahide Kuroki; Takehiko Sasazuki; Senji Shirasawa
CELLULAR & MOLECULAR BIOLOGY LETTERS, 2011年03月, 16(1):89 - 100, 査読有り

Immune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islands
Toshiyuki Tsunoda; Yasuo Takashima; Yoko Tanaka; Takahiro Fujimoto; Keiko Doi; Yumiko Hirose; Midori Koyanagi; Yasuhiro Yoshida; Tadashi Okamura; Masahide Kuroki; Takehiko Sasazuki; Senji Shirasawa
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010年08月, 107(32):14199 - 14204, 査読有り

Three-dimensionally Specific Inhibition of DNA Repair-Related Genes by Activated KRAS in Colon Crypt Model
Toshiyuki Tsunoda; Yasuo Takashima; Takahiro Fujimoto; Midori Koyanagi; Yasuhiro Yoshida; Keiko Doi; Yoko Tanaka; Tanaka; Masahide Kuroki; Takehiko Sasazuki; Senji Shirasawa
NEOPLASIA, 2010年05月, 12(5):397 - U5, 査読有り

Fiber arrangement of the intestinal smooth muscle layers in ammocoetes of Lampetra japonica
Y Tanaka; M Miyoshi; ET Chen
ZOOLOGY, 2002年, 105(1):25 - 30, 査読有り

A Scanning and Transmission Electron Microscopic Study of Contractile Trabecules in the Rat Spleen
Kazuo Kimura; Takami Fusano; Yoko Tanaka
Okajimas Folia Anatomica Japonica, 2001年12月, 78(5):187 - 200, 査読有り

Fenestrated Epithelium of the Pelvic Recess Wall on the Lateral Parenchymal Tissue in the Dog Kidney
Shotaro Nozaki; Takami Fusano; Yoko Tanaka; Masayuki Miyoshi
Okajimas Folia Anatomica Japonica, 2001年12月, 78(5):201 - 210, 査読有り

日本解剖学会

脾洞内皮細胞血球通過機構の解明-内皮細胞ダイナミックスの解析
日本学術振興会, 科学研究費助成事業, 基盤研究(C)
福岡大学
2004年 - 2005年