Antithrombin gamma attenuates macrophage/microglial activation and brain damage after transient focal cerebral ischemia in mice.
Takafumi Nakano; Yoshihiko Nakamura; Keiichi Irie; Shinobu Okano; Mayuka Morimoto; Yuta Yamashita; Tomohiro Kozako; Toshinobu Hayashi; Shin-Ichiro Honda; Koichi Matsuo; Hidetoshi Kamimura; Hiroyasu Ishikura; Takashi Egawa; Kenichi Mishima
Life Sci., Jul. 2020, Refereed

Characterization and pharmacokinetics evaluation of microcomposite particles of alpha lipoic acid/hydrogenated colza oil obtained in supercritical carbon dioxide.
Masathoshi Honjo; Okuraha Yasuhide; Masayoshi Yamada; Sei Higuchi; Kenji Mishima; Tanjina Sharmin; Taku Michael Aida; Takafumi Kato; Makoto Misumi; Tadashi Suetsugu; Hideaki Orii; Keiichi Irie; Kazunori Sano; Kenichi Mishima; Tomomitsu Satho; Takunori Harada
Pharm Dev Technol., Mar. 2020

大麻成分の中枢効果：有用性と危険性.
三島健一; 入江圭一
薬学雑誌, Dec. 2019, Refereed

EP4 receptor-associated protein regulates gluconeogenesis in the liver and is associated with hyperglycemia in diabetic mice.
Sei Higuchi; Risako Fujikawa; Masato Nakatsuji; Mika Yasui; Taichi Ikedo; Manabu Nagata; Kenji Mishima; Keiichi Irie; Michihiro Matsumoto; Masayuki Yokode; Manabu Minami
Physiol Endocrinol Metab., Mar. 2019, Refereed

Goreisan Prevents Brain Edema after Cerebral Ischemic Stroke by Inhibiting Aquaporin 4 Upregulation in Mice
Takafumi Nakano; Chisa Nishigami; Keiichi Irie; Yutaka Shigemori; Kazunori Sano; Yuta Yamashita; Takayuki Myose; Koji Tominaga; Koichi Matsuo; Yoshihiko Nakamura; Hiroyasu Ishikura; Hidetoshi Kamimura; Takashi Egawa; Kenichi Mishima
Journal of Stroke and Cerebrovascular Diseases, 01 Mar. 2018, Refereed

Involvement of Charcot-Marie-Tooth disease gene mitofusin 2 expression in paclitaxel-induced mechanical allodynia in rats
Yuta Yamashita; Keiichi Irie; Akane Kochi; Nami Kimura; Toshinobu Hayashi; Koichi Matsuo; Takayuki Myose; Kazunori Sano; Takafumi Nakano; Yumi Takase; Yoshihiko Nakamura; Tomomitsu Satho; Kenji Mishima; Kenichi Mishima
NEUROSCIENCE LETTERS, Jul. 2017, Refereed

Effects of Teicoplanin on the PT-INR Controlled by Warfarin in Infection Patients.
Takafumi Nakano; Tomomi Nakamura; Yoshihiko Nakamura; Keiichi Irie; Keisuke Sato; Koichi Matsuo; Osamu Imakyure; Kentarou Ogata; Kenichi Mishima; Hidetoshi Kamimura
YAKUGAKU ZASSHI, Jul. 2017, Refereed

Activations of muscarinic M1 receptors in the anterior cingulate cortex contribute to the antinociceptive effect via GABAergic transmission.
Kohei Koga; Yu Matsuzaki; Kenji Honda; Fumihiro Eto; Tomonori Furukawa; Keisuke Migita; Keiichi Irie; Kenichi Mishima; Shinya Ueno
Molecular Pain, Jan. 2017, Refereed

Enhancement and regulation effect of myrcene on antibody response in immunization with ovalbumin and Ag85B in mice
Saori Uyeda; Tanjina Sharmin; Tomomitsu Satho; Keiichi Irie; Mineo Watanabe; Masato Hosokawa; Yukihiro Hiramatsu; Takayuki Koga; Yukihiko Nakashima; Nobuhiro Kashige; Akihisa Toda; Kenji Mishima; Fumio Miake
ASIAN PACIFIC JOURNAL OF ALLERGY AND IMMUNOLOGY, Dec. 2016, Refereed

Effect of Simple Calculation Exercise on Cerebral Blood Oxygenation during a Verbal Memory Task Measured by fNIRS
Makoto Misumi; Kenji Mishima; Hideaki Orii; Tanjina Sharmin; Shinichi Tokunaga; Masashi Haraguchi; Miyuki Nakamura; Takunori Harada; Tadashi Suetsugu; Keiichi Irie; Kenichi Mishima; Tomomitsu Satho
Journal of the Institute of Industrial Applications Engineers, 25 Oct. 2016, Refereed

Change of teicoplanin loading dose requirement for incremental increases of systemic inflammatory response syndrome score in the setting of sepsis.
Takafumi Nakano; Yoshihiko Nakamura; Tohru Takata; Keiichi Irie; Kazunori Sano; Osamu Imakyure; Kenichi Mishima; Koujirou Futagami
Int J Clin Pharm, Aug. 2016, Refereed

Recombinant human soluble thrombomodulin ameliorates cerebral ischemic injury through a high-mobility group box 1 inhibitory mechanism without hemorrhagic complications in mice
Yoshihiko Nakamura; Takafumi Nakano; Keiichi Irie; Kazunori Sano; Junichi Tanaka; Yuta Yamashita; Tomomitsu Satho; Koichi Matsuo; Masayuki Fujioka; Hiroyasu Ishikura; Kenichi Mishima
JOURNAL OF THE NEUROLOGICAL SCIENCES, Mar. 2016, Refereed

Delayed treatment with ADAMTS13 ameliorates cerebral ischemic injury without hemorrhagic complication
Takafumi Nakano; Keiichi Irie; Kazuhide Hayakawa; Kazunori Sano; Yoshihiko Nakamura; Masayoshi Tanaka; Yuta Yamashita; Tomomitsu Satho; Masayuki Fujioka; Carl Muroi; Koichi Matsuo; Hiroyasu Ishikura; Kojiro Futagami; Kenichi Mishima
BRAIN RESEARCH, Oct. 2015, Refereed

Gas-saturated solution process to obtain microcomposite particles of alpha lipoic acid/hydrogenated colza oil in supercritical carbon dioxide.
Mishima K; Honjo M; Sharmin T; Ito S; Kawakami R; Kato T; Misumi M; Suetsugu T; Orii H; Kawano H; Irie K; Sano K; Mishima K; Harada T; Ouchi M
Pharm Dev Technol., 29 May 2015, Refereed

Extraction of Resveratrol from Melinjo (Gnetum gnemon L.) Seeds Using Mixtures of Liquid Carbon Dioxide and Ethanol
Kenji Mishima; Yusraini Dian Inayati Siregar; Hirofumi Kawamura; Ryo Kawakami; Shota Ito; Yuuta Inoue; Tetsuya Hirota; Takunori Harada; Takafumi Kato; Makoto Misumi; Tadashi Suetsugu; Keiichi Irie; Kenichi Mishima; Salim Mustofa; Fauziyah Hasanah; Hilyatuz Zaharo; Lily Surayya Eka Putri; Agus Salim
SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, 2015, Refereed

Effects of Comb Tooth Cap Medicinal Mushroom, Hericium ramosum (Higher Basidiomycetes) Mycelia on DPPH Radical Scavenging Activity and Nerve Growth Factor Synthesis.
Suruga K; Kadokura K; Sekino Y; Nakano T; Matsuo K; Irie K; Mishima K; Yoneyama M; Komatsu Y
Int J Med Mushrooms., 2015, Refereed

The anti-inflammatory effects of a high-frequency oligodeoxynucleotide from the genomic DNA of Lactobacillus casei
Yukihiro Hiramatsu; Tomomitsu Satho; Mika Hyakutake; Keiichi Irie; Kenichi Mishima; Fumio Miake; Nobuhiro Kashige
INTERNATIONAL IMMUNOPHARMACOLOGY, Nov. 2014, Refereed

The anti-inflammatory effects of a high-frequency oligodeoxynucleotide from the genomic DNA of Lactobacillus casei (登録用)
Yukihiro Hiramatsu; Tomomitsu Satho; Mika Hyakutake; Keiichi Irie; Kenichi Mishima; Fumio Miake; Nobuhiro Kashige
International Immunopharmacology, Nov. 2014, Refereed

Recombinant fusion protein of cholera toxin B subunit with YVAD secreted by Lactobacillus casei inhibits lipopolysaccharide-induced caspase-1 activation and subsequent IL-1 beta secretion in Caco-2 cells
Yukihiro Hiramatsu; Masatatsu Yamamoto; Tomomitsu Satho; Keiichi Irie; Akiko Kai; Uyeda Saori; Yuki Fukumitsu; Akihisa Toda; Takeshi Miyata; Fumio Miake; Takeshi Arakawa; Nobuhiro Kashige
BMC Biotechnology, May 2014, Refereed

Effect of ADAMTS-13 on cerebrovascular microthrombosis and neuronal injury after experimental subarachnoid hemorrhage
C. Muroi; M. Fujioka; K. Mishima; K. Irie; Y. Fujimura; T. Nakano; J. Fandino; E. Keller; K. Iwasaki; M. Fujiwara
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Apr. 2014, Refereed

Expression and secretion of cholera toxin B subunit in lactobacilli
Takahiro Okuno; Nobuhiro Kashige; Tomomitsu Satho; Keiichi Irie; Yukihiro Hiramatsu; Tanjina Sharmin; Yuki Fukumitsu; Saori Uyeda; Seitaro Yamada; Tetsuya Harakuni; Takeshi Miyata; Takeshi Arakawa; Masumi Imoto; Akihisa Toda; Yukihiko Nakashima; Fumio Miake
Biological and Pharmaceutical Bulletin, Jun. 2013, Refereed

Bioimaging application of highly luminescent silica-coated ZnO-nanoparticle quantum dots with biotin
Kiyoshi Matsuyama; Neil Ihsan; Keiichi Irie; Kenichi Mishima; Tetsuya Okuyama; Hiroyuki Muto
Journal of Colloid and Interface Science, 01 Jun. 2013, Refereed

Pyriproxyfen enhances the Immunoglobulin G immune response in mice
Tanjina Sharmin; Tomomitsu Satho; Keiichi Irie; Mineo Watanabe; Masato Hosokawa; Yukihiro Hiramatsu; Parimal Talukder; Takahiro Okuno; Shodai Tsuruda; Saori Uyeda; Yuki Fukmits; Yukie Tamura; Yukihiko Nakashima; Masumi Imoto; Akihisa Toda; Nobuhiro Kashige; Fumio Miake
Microbiology and Immunology, Apr. 2013, Refereed

Differences in TLR9-dependent inhibitory effects of H2O2-induced IL-8 secretion and NF-kappa B/I kappa B-alpha system activation by genomic DNA from five Lactobacillus species
Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Shota Shiimura; Takahiro Okuno; Tanjina Sharmin; Saori Uyeda; Yuki Fukumitsu; Yukihiko Nakashima; Fumio Miake; Nobuhiro Kashige
MICROBES AND INFECTION, Feb. 2013, Refereed

Ameliorative Effects of Telmisartan on the Inflammatory Response and Impaired Spatial Memory in a Rat Model of Alzheimer's Disease Incorporating Additional Cerebrovascular Disease Factors
Taro Shindo; Kotaro Takasaki; Kanako Uchida; Rika Onimura; Kaori Kubota; Naoki Uchida; Keiichi Irie; Shutaro Katsurabayashi; Kenichi Mishima; Ryoji Nishimura; Michihiro Fujiwara; Katsunori Iwasaki
BIOLOGICAL & PHARMACEUTICAL BULLETIN, Dec. 2012, Refereed

Differences in TLR9-dependent inhibitory effects of H(2)O(2)-induced IL-8 secretion and NF-kappa B/I kappa B-alpha system activation by genomic DNA from five Lactobacillus species.
Hiramatsu Y; Satho T; Irie K; Shiimura S; Okuno T; Sharmin T; Uyeda S; Fukumitsu Y; Nakashima Y; Miake F; Kashige N
Microbes Infect, Nov. 2012, Refereed

Hypothalamic 2-arachidonoylglycerol regulates multistage process of high-fat diet preferences.
Higuchi S; Irie K; Yamaguchi R; Katsuki M; Araki M; Ohji M; Hayakawa K; Mishima S; Akitake Y; Matsuyama K; Mishima K; Mishima K; Iwasaki K; Fujiwara M
PLoS One, Jun. 2012, Refereed

Elevation of dopamine level reduces host-seeking activity in the adult female mosquito Aedes albopictus
Yuki Fukumitsu; Keiichi Irie; Tomomitsu Satho; Hitoshi Aonuma; Hamady Dieng; Abu Hassan Ahmad; Yukihiko Nakashima; Kenichi Mishima; Nobuhiro Kashige; Fumio Miake
PARASITES & VECTORS, May 2012, Refereed

Transparent polymeric hybrid film of ZnO nanoparticle quantum dots and PMMA with high luminescence and tunable emission color
Kiyoshi Matsuyama; Kenji Mishima; Takafumi Kato; Keiichi Irie; Kenichi Mishima
JOURNAL OF COLLOID AND INTERFACE SCIENCE, Feb. 2012, Refereed

ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia-reperfusion injury
Fujioka M; Nakano T; Hayakawa K; Irie K; Akitake Y; Sakamoto Y; Mishima K; Muroi C; Yonekawa Y; Banno F; Kokame K; Miyata T; Nishio K; Okuchi K; Iwasaki K; Fujiwara M; Siesjö BK
Neurol Sci, Jan. 2012, Refereed

Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors
Sei Higuchi; Makiko Ohji; Maiko Araki; Riyo Furuta; Mai Katsuki; Ryuji Yamaguchi; Yoshiharu Akitake; Kiyoshi Matsuyama; Keiichi Irie; Kenji Mishima; Kenichi Mishima; Katsunori Iwasaki; Michihiro Fujiwara
BEHAVIOURAL BRAIN RESEARCH, Jan. 2011, Refereed

Trace metal zinc stimulates secretion of antimicrobial peptide LL-37 from Caco-2 cells through ERK and p38 MAP kinase
Parimal Talukder; Tomomitsu Satho; Keiichi Irie; Tanjina Sharmin; Dieng Hamady; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
INTERNATIONAL IMMUNOPHARMACOLOGY, Jan. 2011, Refereed

Trace metal zinc stimulates secretion of antimicrobial peptide LL-37 from Caco-2 cells through ERK and p38 MAP kinase
Parimal Talukder; Tomomitsu Satho; Keiichi Irie; Tanjina Sharmin; Dieng Hamady; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
INTERNATIONAL IMMUNOPHARMACOLOGY, Jan. 2011, Refereed

Sex differences in the benefits of rehabilitative training during adolescence following neonatal hypoxia-ischemia in rats.
Tsuji M; Aoo N; Harada K; Sakamoto Y; Akitake Y; Irie K; Mishima K; Ikeda T; Fujiwara M
Exp Neurol, Dec. 2010, Refereed

Inhibition of reactive astrocytes with fluorocitrate retards neurovascular remodeling and recovery after focal cerebral ischemia in mice
Kazuhide Hayakawa; Takafumi Nakano; Keiichi Irie; Sei Higuchi; Masayuki Fujioka; Kensuke Orito; Katsunori Iwasaki; Guang Jin; Eng H. Lo; Kenichi Mishima; Michihiro Fujiwara
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, Apr. 2010, Refereed

Ameliorating effects of Kangen-karyu on neuronal damage in rats subjected to repeated cerebral ischemia.
Pu F; Kaneko T; Enoki M; Irie K; Okamoto T; Sei Y; Egashira N; Oishi R; Mishima K; Kamimura H; Iwasaki K; Fujiwara M
J Nat Med, Apr. 2010, Refereed

fNIRSによる言語流暢課題遂行時の前頭前野における脳血液量の測定
三島健司; 松山清; 加藤貴史; 末次正; 荒牧重登; 入江圭一; 三島健一; 藤原道弘; 藍浩之; 阿比留正弘
福岡大学工学集報, Mar. 2010

ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion
Masayuki Fujioka; Kazuhide Hayakawa; Kenichi Mishima; Ai Kunizawa; Keiichi Irie; Sei Higuchi; Takafumi Nakano; Carl Muroi; Hidetada Fukushima; Mitsuhiko Sugimoto; Fumiaki Banno; Koichi Kokame; Toshiyuki Miyata; Michihiro Fujiwara; Kazuo Okuchi; Kenji Nishio
BLOOD, Feb. 2010, Refereed

The cannabinoid 1-receptor silent antagonist O-2050 attenuates preference for high-fat diet and activated astrocytes in mice.
Higuchi S; Irie K; Mishima S; Araki M; Ohji M; Shirakawa A; Akitake Y; Matsuyama K; Mishima K; Mishima K; Iwasaki K; Fujiwara M
J Pharmcol Sci, Feb. 2010, Refereed

Reducing acyl migration during purification of 2-arachidonoylglycerol from biological samples before gas chromatography mass spectrometry analysis
analytical sciences, 2010, Refereed

Delta(9)-tetrahydrocannabinol enhances an increase of plasma corticosterone levels induced by forced swim-stress.
Sano K; Koushi E; Irie K; Higuchi S; Tsuchihashi R; Kinjo J; Egashira N; Oishi R; Uchida N; Nagai H; Nishimura R; Tanaka H; Morimoto S; Mishima K; Iwasaki K; Fujiwara M
Biol Pharm Bull, Dec. 2009, Refereed

Therapeutic time window of cannabidiol treatment on delayed ischemic damage via high-mobility group box1-inhibiting mechanism.
Hayakawa K; Irie K; Sano K; Watanabe T; Higuchi S; Enoki M; Nakano T; Harada K; Ishikane S; Ikeda T; Fujioka M; Orito K; Iwasaki K; Mishima K; Fujiwara M
Biol Pharm Bull, Sep. 2009

Extraction of Silymarins from Milk Thistle Seeds Using Supercritical Carbon Dioxide with Methanol
M. HONJO; K MISHIMA; K. MATSUYAMA; H.SEKIGUCHI; S.ANDO; K.RIE; K.MISHIMA; M.FUJIWARA
Solvent Extraction Research and Development, Japan, Apr. 2009, Refereed

Neuroprotective Effects of Kangen-karyu on Spatial Memory Impairment in an 8-Arm Radial Maze and Neuronal Death in the Hippocampal CA1 Region Induced by Repeated Cerebral Ischemia in Rats
Fengling Pu; Kyoko Motohashi; Tomohiro Kaneko; Yurika Tanaka; Naorni Manome; Keiichi Irie; Jirou Takata; Nobuaki Egashira; Ryozo Oishi; Takuya Okamoto; Yasuo Sei; Takako Yokozawa; Kenichi Mishima; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2009, Refereed

Cannabidiol prevents a post-ischemic injury progressively induced by cerebral ischemia via a high-mobility group box1-inhibiting mechanism
Kazuhide Hayakawa; Kenichi Mishima; Keiichi Irie; Mai Hazekawa; Shohei Mishima; Masayuki Fujioka; Kensuke Orito; Nobuaki Egashira; Shutaro Katsurabayashi; Kotaro Takasaki; Katsunori Iwasaki; Michihiro Fujiwara
NEUROPHARMACOLOGY, Dec. 2008, Refereed

Cannabidiol potentiates pharmacological effects of Delta(9)-tetrahydrocannabinol via CB1 receptor-dependent mechanism
Kazuhide Hayakawa; Kenichi Mishima; Mai Hazekawa; Kazunori Sano; Keiichi Irie; Kensuke Orito; Takashi Egawa; Yoshihisa Kitamura; Naoki Uchida; Ryoji Nishimura; Nobuaki Egashira; Katsunori Iwasaki; Michihiro Fujiwara
BRAIN RESEARCH, Jan. 2008, Refereed

Delta(9)-tetrahydrocannabinol-induced catalepsy-like immobilization is mediated by decreased 5-HT neurotransmission in the nucleus accumbens due to the action of glutamate-containing neurons
K. Sano; K. Mishima; E. Koushi; K. Orito; N. Egashira; K. Irie; K. Takasaki; S. Katsurabayashi; K. Iwasaki; N. Uchida; T. Egawa; Y. Kitamura; R. Nishimura; M. Fujiwara
NEUROSCIENCE, Jan. 2008, Refereed

Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism
Kazuhide Hayakawa; Kenichi Mishima; Masanori Nozako; Mai Hazekawa; Keiichi Irie; Masayuki Fujioka; Kensuke Orito; Kohji Abe; Nobuyoshi Hasebe; Nobuaki Egashira; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF NEUROCHEMISTRY, Sep. 2007, Refereed

Neuroprotective effects of quercetin and rutin on spatial memory impairment in an 8-arm radial maze task and neuronal death induced by repeated cerebral ischemia in rats
Fengling Pu; Kenichi Mishima; Keiichi Irie; Kyouko Motohashi; Yurika Tanaka; Kensuke Orito; Takashi Egawa; Yoshihisa Kitamura; Nobuaki Egashira; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, Aug. 2007, Refereed

Down regulation of the L-type Ca2+ channel, GRK2, and phosphorylated phospholamban: protective mechanisms for the denervated failing heart.
Yatani A; Shen YT; Yan L; Chen W; Kim SJ; Sano K; Irie K; Vatner SF; Vatner DE
J Mol Cell Cardiol, Mar. 2006, Refereed

Dual effects of mesenteric lymph isolated from rats with burn injury on contractile function in rat ventricular myocytes.
Yatani A; Xu DZ; Irie K; Sano K; Jidarian A; Vatner SF; Deitch EA
Am J Physiol Heart Circ Physiol, Feb. 2006, Refereed

Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice.
Zhai P; Yamamoto M; Galeotti J; Liu J; Masurekar M; Thaisz J; Irie K; Holle E, Yu X; Kupershmidt S; Roden DM; Wagner T; Yatani A; Vatner DE; Vatner SF; Sadoshima J
J Clin Invest, Nov. 2005, Refereed

RhoA GTPase regulates L-type Ca2+ currents in cardiac myocytes.
Yatani A; Irie K; Otani T; Abdellatif M; Wei L
Am J Physiol Heart Circ Physiol, Feb. 2005, Refereed

Post-ischemic treatment with toki-shakuyaku-san (tang-gui-shao-yao-san) prevents the impairment of spatial memory induced by repeated cerebral ischemia in rats.
Pu F; Mishima K; Egashira N; Akiyoshi Y; Liu AX; Sano K; Irie K; Ishibashi D; Hatip-Al-Khatib I; Iwasaki K; Kurauchi K; Iwasaki K; Fujiwara M
Am J Clin Med, 2005, Refereed

Protective effect of buckwheat polyphenols against long-lasting impairment of spatial memory associated with hippocampal neuronal damage in rats subjected to repeated cerebral ischemia
FL Pu; K Mishima; N Egashira; K Iwasaki; T Kaneko; T Uchida; K Irie; D Ishibashi; H Fujii; K Kosuna; M Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, Apr. 2004, Refereed

Insights into cardioprotection obtained from study of cellular Ca2+ handling in myocardium of true hibernating mammals.
Yatani A; Kim SJ; Kudej RK; Wang Q; Depre C; Irie K; Kranias EG; Vatner SF; Vatner DE
Am J Physiol Heart Circ Physiol, Feb. 2004, Refereed

Non-NMDA mechanism in the inhibition of cellular apoptosis and memory impairment induced by repeated ischemia in rats
K Iwasaki; EH Chung; E Egashira; Hatip-Al-Khatib, I; K Mishima; T Egawa; K Irie; M Fujiwara
BRAIN RESEARCH, Jan. 2004, Refereed

Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats
K Iwasaki; K Mishima; N Egashira; IH Al-Khatib; D Ishibashi; K Irie; H Kobayashi; T Egawa; M Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, Oct. 2003, Refereed

Neurally-mediated increase in calcineurin activity regulates cardiac contractile function in absence of hypertrophy
JA Li; A Yatani; SJ Kim; G Takagi; K Irie; QH Zhang; Karoor, V; CL Hong; GP Yang; J Sadoshima; C Depre; DE Vatner; MJ West; SF Vatner
CARDIOVASCULAR RESEARCH, Sep. 2003, Refereed

Involvement of bcl-family expression in the spatial memory impairment induced by repeated ischemia.
Irie K; Mishima K; Ishibashi D; Egashira N; Iwasaki K; Fujiwara M
Life Sci, Dec. 2002

Hypoxia enhances beta-amyloid-induced apoptosis in rat cultured hippocampal neurons.
Egashira N; Iwasaki K; Ishibashi M; Hatip-Al-Khatib I; Wolozin B; Mishima K; Irie K; Fujiwara M
Jpn J Pharmacol, Dec. 2002, Refereed

血小板凝集因子vWF切断酵素ADAMTS13とそのマルチドメインによる脳保護効果の解明
中野貴文; 入江圭一
福岡大学産学官連携研究機関加齢脳科学研究所 2013年度研究成果報告書：37-49、2014, Mar. 2014

Long-term treatment with recombinant human soluble thrombomodulin improves ischemic brain damage via regulating systemic HMGB1 levels in mice
Nakano T; Nakamura Y; Irie K; Yamashita Y; Myose T; Takase Y; Matsuo K; Kamimura H; Ishikura H; Sano K; Egawa T; Mishima K
Neuroscience 2018, 05 Nov. 2018, Society of Neuroscience

脳虚血-再灌流障害モデルを用いた脳浮腫に対する五苓散の効果
IRIE Keiichi; SATHO Tomomitsu
第33回和漢医薬学会学術大会, 28 Aug. 2016

Δ9-Tetrahydrocannabinol とMethamphetamine が誘発するラットの超音波発声の比較
MYOSE Takayuki; IRIE Keiichi; YAMASHITA Yuta; TEORAMAE Yuki; HIRANO Mari; NAKASHIMA Arisa; TANAKA Marino; TSUTIHASHI Ryota; KINJO Junei; SATHO Tomomitsu; SANO Kazunori; HONDA Kenji; MISHIMA Kenichi
日本薬学会第136年会, 29 Mar. 2016

オキサリプラチン誘発性末梢神経障害ラットにおける神経変性疾患Amyotrophic-Lateral-Screlosis原因遺伝子の動態
HIRAYAMA Minako; YAMASHITA Yuta; IRIE Keiichi; MYOSE Takayuki; NAKANO Takafumi; TAKASE Yumi; HARA Koyomi; IWAHASHI Risa; HYAKUTAKE Mika; HAYASHI Nobuteru; MATSUO Koichi; SATHO Tomomitsu; MISHIMA Kenji; SANO Kazunori; HONDA Kenji; MISHIMA Kenichi
日本薬学会第136年会, 29 Mar. 2016

がん化学療法に伴う末梢神経障害におけるCharcot-Marie-Tooth病原因遺伝子の関与
幸地茜; 山下郁太; 入江圭一; 明瀬孝之; 中野貴文; 高瀬友美; 原暦; 岩橋理紗; 百武美香; 林稔展; 松尾宏一; 佐藤朝光; 三島健司; 佐野和憲; 本多健治; 三島健一
日本臨床腫瘍薬学会学術大会2016, 13 Mar. 2016

TNFαは糖尿病マウスにおいて機械刺激性疼痛過敏に関与する
衛藤史博; 本多健治; 東翔子; 浅田歩; 入江圭一; 右田啓介; 三島健一
第89回日本薬理学会年会, Mar. 2016

ヒトスジシマカマイクロアレイを用いた宿主探索行動を制御する遺伝子の調査
福光由起; 佐藤朝光; 入江圭一; 上田紗織; 百武美香; 弟子丸正伸; 中島幸彦; 鹿志毛信広; 見明史雄
日本昆虫学会第76回大会 / 第60回日本応用動物昆虫学会大会 合同大会, Mar. 2016

ヒトスジシマカ白眼変異体の性質について
奥田晶子; 福光由起; 米村敦子; 村上義哉; 鹿志毛信広; 見明史雄; 佐藤朝光; 中島幸彦; 入江圭一
日本薬学会第136年会, Mar. 2016

白金系抗がん剤オキサリプラチンとシュウ酸がCharcot-Marie-Tooth病原因遺伝子に与える影響
山下郁太; 寺岡里織; 入江圭一; 岩橋理紗; 吉武麻耶; 明瀬孝之; 原暦; 百武美香; 市丸優希; 林稔展; 松尾宏一; 佐藤朝光; 三島健司; 岩崎克典; 三島健一
第31回日本薬学会九州支部会, 06 Dec. 2014

Influence of oral administration of mosquito isolated enterococcus bacteria to dextran sodium sultate induced murine colitis
Mika Hyakutake; Tomomitsu Satho; Tomomi Nakamura; Keiichi Irie; Yukihiro Hiramatsu; Saori Uyeda; Yuki Fukumitsu; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
Joint International Tropical Medicine Meeting 2014, 02 Dec. 2014

ティーエスワン誘発性食欲不振モデルラットの作製と解析
岩橋理紗; 山下郁太; 入江圭一; 寺岡里織; 吉武摩耶; 中野貴文; 林稔展; 佐藤朝光; 松尾宏一; 岩崎克典; 三島健一
第52回 日本癌治療学会学術集会, 28 Aug. 2014

オキサリプラチン誘発性末梢神経障害ラットのCharcot-Marie-Tooth病原因遺伝子の動態
寺岡里織; 入江圭一; 山下郁太; 岩橋理紗; 吉武摩耶; 明瀬孝之; 原暦; 百武美香; 市丸優希; 林稔展; 松尾宏一; 佐藤朝光; 三島健司; 岩崎克典; 三島健一
The 52nd Annual Meeting of Japan Society of Clinical Oncology, 28 Aug. 2014

ヒトスジシマカにおけるドパミンレセプターの同定
Y. Fukumitsu; K. Irie; T. Satho; S. Uyeda; Nakashima; N. Kashige; F. Miake
2014 ICN / JSCPB, 29 Jul. 2014

蚊の中腸から単離したEnterococcus属乳酸菌の新種提案
Saori Uyeda; Tomomitsu Satho; Keiichi Irie; Yukihiro Hiramatsu; Yuki Fukumitsu; Yukiko Okuyama; Manami Fukuda; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
Japan Society forLactic Acid Bacteria 2014, 17 Jul. 2014

オクトパミン量の変化がヒトスジシマカ雌の宿主探索行動へ与える影響
Y. Fukumitsu; A. Yonemura; K. Irie; T. Satho; S. Uyeda; Y. Hiramatsu; Y. Nakashima; K. Mishima; N. Kashige; F. Miake
Seventh International Symposium on Molecular Insect Science, 14 Jul. 2014

クルマエビ腸管由来乳酸菌のヒト結腸癌由来Caco-2細胞における 抗菌ペプチド発現誘導作用
梶原由紀; 平松征洋; 佐藤朝光; 宇高彩奈; 椎村翔太; 入江圭一; 上田紗織; 前田稔; 中島幸彦; 鹿志毛信広; 見明史雄
The 134th Annual Meeting of the Pharmaceutical Society of Japan, 28 Mar. 2014

脳梗塞における多機能サイトカインであるOncostatin M受容体の発現変化
Yuka Oishi; Keiichi Irie; Takafumi Nakano; Yuri Narazaki; Masaaki Tanaka; Tomomitsu Satho; Kojiro Futagami; kenichi Mishima; Katunori Iwasaki
The 134th Annual Meeting of the Pharmaceutical Society of Japan, 28 Mar. 2014

蚊から単離されたEneterococcus属菌の抗生物質感受性
Yukiko Okuyama; Yukihiko Nakashima; Manami Fukuda; Tomomitsu Satho; Keiichi Irie; Yukihiro Hiramatsu; Saori Uyeda; Yuki Fukumitsu; Nobuhiro Kashige; Fumio Miake
The 134th Annual Meeting of the Pharmaceutical Society of Japan, 28 Mar. 2014

Identification of Enterococcus Bacteria isolated from mosquito
Saori Uyeda; Tomomitsu Satho; Keiichi Irie; Yukihiro Hiramatsu; Yuki Fukumitsu; Yukiko Okuyama; Manami Fukuda; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
Tropical Medicine Meeting 2013, 11 Dec. 2013

乳酸菌由来DNAの腸管における抗炎症作用
Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Mika Hyakutake; Fumio Miake; Nobuhiro kashige
The 30th Annual Meeting of the Pharmaceutical Society of Japan, Kyushu Branch, 07 Dec. 2013

脂肪嗜好性に対する高脂肪食摂取期間が及ぼすカンナビノイドシステムの変化
Yuta Yamashita; Keiichi Irie; Ryuji Yamashita; Sei Higuchi; Takafumi Nakano; Toshinobu Hayasi; Koichi, Matsuo; Tomomitsu Satho; Kiyoshi Matsuyama; Kenji Mishima; Shutaro Katsurabayashi; Kaori Kubota; Kotaro Takasaki; Kenichi Mishima; Katsunori Iwasaki
The 66th Annual Meeting of the Japanese Pharmacological Society, West-South Branch, 16 Nov. 2013

マウスにおけるDSS誘導性大腸炎の病態とTREM-1/TREM-2の発現量比の一致
Saori Egawa; Mika Hyakutake; Tomomi Nakamura; Yukihiro Hiramatsu; Saori Ueda; Keiichi Irie; Tomomitsu Satho; Yukihiko Nakashima; Kenichi Mishima; Nobuhiro Kashige; Fumio Miake
The 86th Annual Meeting of the Japanese Biochemical Society, 11 Sep. 2013

ミルセンによるアジュバント効果とその作用機序
末延竜哉; 大森果奈; Tanjina Sharmin; 佐藤朝光; 入江圭一; 渡邉峰雄; 細川雅人; 平松征洋; 上田沙織; 福光由起; 中島幸彦; 井本真澄; 戸田晶久; 鹿志毛信広; 見明史雄
The 30th Annual Meeting of Medical and Pharmaceutical Society for WAKAN-YAKU, 31 Aug. 2013

Oligodeoxynucleotide 5'-TTTTGCCG-3' from Lactobacillus casei inhibits intestinal inflammation
Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Shota Shiimura; Yukihiko Nakashima; Fumio Miake; Nick Carpino; Nobuhiro Kashige
World Biotechnology Congress 2013, 04 Jun. 2013

myrceneによるマウスのIgGの産生誘導とその機序
Kana Oomori; Tanjina Sharmin; Tomomitsu Satho; Keiichi Irie; Mineo Watanabe; Masato Hosokawa; Yukihiro Hiramasu; Saori Uyeda; Yuki fukumitsu; Yukihiko Nakashima; Akihisa Toda; Nobuhiro Kashige; Fumio Miake
The 133th Annual Meeting of the Pharmaceutical Society of Japan, 30 Mar. 2013

DSS誘発マウス大腸炎における雌雄差
Mika Hyakutake; Yukie Tamura; Saori Egawa; Keiichi Irie; Tomomitsu Satho; Yukihiro Hiramatsu; Saori Ueda; Yuki, Fukumitsu; Yukihiko, Nakashima; Kenichi Mishima; Michihiro, Fujiwara; Nobuhiro Kashige; Fumio Miake
日本薬学会第133年会, 27 Mar. 2013

Lactobacillus caseiのゲノムDNAに含まれる抗炎症作用を持つオリゴデオキシヌクレオチドの特定と作用機構の解明
Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Shouta Shiimura; Yukihiko Nakashima; Fumio Miake; Nobuhiro Kashige
Annual Meeting of Japan Society for Bioscence, Biotechnology, and Agrochemistry 2013, 25 Mar. 2013

A decrease of host-seeking behavior in virgin female appears without elevation of dopamine levels in the adult mosquito Aede albopictus
Yuki Fukmits; Keiichi Irie; Tomomitsu Satho; Yukihiko Nakashima; Kenichi Mishima; Nobuhiro Kashige; Fumio Miake
Joint International Tropical Medicine Meeting 2012, 12 Dec. 2012

ヒト結腸癌由来Caco-2細胞における炎症誘発時のProgranulin発現と分泌
Ayana Utaka; Yukihiro Hiramatsu; Tomomitsu Satho; Shota Shiimura; Keiichi Irie; Ayumi Furukawa; Kenichi Mishima; Michihiro Fujiwara; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
The 29th Annual Meeting of the Pharmaceutical Society of Japan, Kyushu Branch, 08 Dec. 2012

乳酸菌ゲノムDNA由来の抗炎症作用を持つオリゴデオキシヌクレオチドの特定
Shota Shiimura; Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Ayana Utaka; Saori Uyeda; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
The 29th Annual Meeting of the Pharmaceutical Society of Japan, Kyushu Branch, 08 Dec. 2012

The possibility of Pyriproxyfen as an adjuvant to promote Th1 immune responses
Tanjina Sharmin; Tomomitsu Satho; Keiichi Irie; Mineo Watanabe; Masato Hosokawa; Yukihiro Hiramatsu; Parimal Talukder; Takahiro Okuno; Shodai Tsuruda; Saori Uyeda; Yuki Fukmits; Yukihiko Nakashima; Masumi Imoto; Akihisa Toda; Nobuhiro Kashige; Fumio Miake
The 53th Annual Meeting of the Japanese Society of Tropical Medicine, 06 Sep. 2012

5種類のLactobacillus属乳酸菌由来ゲノムDNAの抗炎症症作用機構に関する研究
Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Shorta Shimura; Yukihiko Nakasshima; Fumio Miake; Nobuhiro Kashige
The 16th Annual Meeting of Intestinal Microbiology, 14 Jun. 2012

Changes in progranulin expression following focal cerebral ischemia associated with microglial activation in mice
Ayumi Furukawa; Keiichi Irie; Yoshiharu Akitake; Masato Hosokawa; Takafumi Nakano; Carl Muroi; Yuya Sakamoto; Yukihiro Hiramatsu; Saori Uyeda; Yuki Fukumitsu; Tomomitsu Satho; Nobuhiro Kashige; Fumio Miake; Kenichi Mishima; Katsunori Iwasaki; Michihiro Fujiwara
The 89th Annual Meeting of the Physiological Society of Japan, 29 Mar. 2012

乳酸菌由来ゲノムDNAの抗炎症作用機構に関する研究
Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Shota Shiimura; Takahiro Okuno; Tanjina Sharimin; Yuki Fukumitsu; Saori Uyeda; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
Annual Meeting of Japan Scoiety for Bioscience, Biotechnology, and Agrochemistry 2012, 25 Mar. 2012

Pyriproxyfen induces Ig G immuno response in BALB/c mice.
Tanjina Sharmin; Tomomitsu Satho; Keiichi Irie; Mineo Watanabe; Yukihiro Hiramatsu; Parimal Talukder; Takahiro Okuno; Shodai Tsuruda; Saori Uyeda; Yukie Tamura; Saori Egawa; Kana Omori; Yukihiko Nakashima; Reiko Eyanagi; Akihisa Toda; Nobuhiro Kashige; Fumio Miake
第39回薬物活性シンポジウム, 21 Nov. 2011

2-Arachidonylglycerol protects against infection by secretion of antimicrobial peptides from the intestinal tract
Saori Uyeda; Keiichi Irie; Takahiro Okuno; Shodai Tsuruda; Mari Ioki; Yukie Tamura; Tomomitsu Satho; Kenichi Mishima; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
IUMS 2011 Sapporo, 06 Sep. 2011

ウコン含有生薬クルクミンが腸管内の自然免疫に与える影響
赤司 唯; 頭島 美幸; 入江 圭一; 佐藤 朝光; 中島 幸彦; 三島 健一; 藤原 道弘; 鹿志毛 信広; 見明 史雄
第28回和漢医薬学会学術大会, 27 Aug. 2011

L-DOPA treatment of adult female Aedes albopictus mosquitoes suggests a relationship between blood-feeding activity and dopamine level
Yuki Fukumitsu; Keiichi Irie; Tomomitsu Satho; Yukihiko Nakashima; Kenichi Mishima; Nobuhiro Kashige; Fumio Miake
8th International Congress of Comparative Physiology and Biochemistry, 03 Jun. 2011

蚊成虫雌における吸血行動と脳内Dopamineの経日的変動の相関性
福光 由起; 入江 圭一; 佐藤 朝光; 鹿志毛 信広; 見明 史雄
第63回日本衛生動物学会, 14 Apr. 2011

Cholera Toxin B と乳酸菌を融合した2ステップ腸管内DDSの開発
奥野 隆啓; 平松 征洋; 入江 圭一; 宮田 健; 戸田 晶久; 佐藤 朝光; 繪柳 玲子; 新川 武; 中島 幸彦; 鹿志毛 信広; 見明 史雄
The 131th Annual Meeting of the Pharmaceutical Society of Japan, 28 Mar. 2011

脂肪酸によるヒト大腸上皮細胞からの抗菌ペプチドLL-37の発現誘導
飯岡 利規; 入江 圭一; Talukder Parimal; 佐藤 朝光; 中島 幸彦; 鹿志毛 信広; 見明 史雄
日本薬学会第131年会, 28 Mar. 2011

2-arachidonylglycerolの腸管病原微生物に対する感染防御への有効性
上田紗織; 入江圭一; 佐藤朝光; 三島健一; 鶴田翔大; 五百木真里; 田村幸恵; 奥野隆啓; 中島幸彦; 岩崎克典; 鹿志毛信広; 藤原道弘; 見明史雄
日本薬学会第131年会, 28 Mar. 2011

亜鉛によるCaco-2細胞からの抗菌ペプチドLL-37の発現誘導
佐藤 朝光; Parimal Talukder; Tanjina Sharmin; 入江 圭一; 中島 幸彦; 鹿志毛 信広; 見明 史雄
第14回 日本病態栄養学会 年次学術集会, 15 Jan. 2011

Trace metal zinc stimulates secretion of antimicrobial peptide LL-37 from Caco-2 cell.
Parimal Talukder; 佐藤 朝光; Tanjina Sharmin; 入江 圭一; 中島 幸彦; 鹿志毛 信広; 見明 史雄
The 27th Annual Meeting of the Pharmaceutical Society of Japan, Kyushu Branch, 12 Dec. 2010

ヒト肺上皮細胞を使用した精油による抗菌ペプチド発現誘導の確認
園田 結理; 瀧下 達也; 頭島 美幸; 佐藤 朝光; 入江 圭一; 中島 幸彦; 鹿志毛 信広; 見明 史雄
The 27th Annual Meeting of the Pharmaceutical Society of Japan, Kyushu Branch, 12 Dec. 2010

C6/36細胞におけるMet遺伝子の部分配列の決定
倉重友和; 佐藤朝光; 福光由起; 入江圭一; 中島幸彦; 鹿志毛信広; 見明史雄
第60回日本衛生動物学会南日本支部大会, 06 Nov. 2010

内因性カンナビノイドによる抗菌ペプチドの発現誘導作用
長戸 麻実; 榎木 麻希子; 入江 圭一; 秋武 義治; 三島 健一; 佐藤 朝光; 鹿志毛 信広; 見明 史雄; 岩崎 克典; 藤原 道弘
日本薬学会 第130年会, 30 Mar. 2010

超臨界二酸化炭素中での超音波を用いた再生医療用細胞外マトリックスの生成
三島健司; 松山清; 入江圭一; 三島健一; 藤原道弘
化学工学会第75年会,K316(鹿児島大), 20 Mar. 2010

内因性カンナビノイド処置ヒト肺上皮細胞株A549における自然免疫賦活作用の発見
榎木麻希子; 入江圭一; 佐藤朝光; 園田結理; 三島健一; 鹿志毛信広; 見明史雄; 藤原道弘
第25回日本薬学会九州支部会, 13 Dec. 2009

Challenge of Interdisciplinary and Integrated Education of Engineering, Medicine, Pharmacology, and Economics in Fukuoka University
K. Mishima; T. Kato; S. Aramaki; K. Irie; K. Mishima; M. Fujiwara; K. Tachibana; K.Saku; M. Abiru; K. Nishijima
ITK-FUKUOKA2009, p11, 07 Nov. 2009

CTB分泌乳酸菌を用いた2ステップ腸管内DDSの開発
宮田健; 奧野隆啓; 平松征洋; 入江圭一; 戸田昌久; 佐藤朝光; 檜柳玲子; 新川武; 中島幸彦; 鹿志毛信宏; 見明史雄
第50回日本熱帯医学会, 22 Oct. 2009

Binary Solid-Liquid-Gas Equilibrium of α-Lipoic Acid/CO2 and Hydrogenated Colza Oil/CO2 Systems
M. Honjo; K. Mishima; K. Mastuyama; K. Irie; K. Mishima; M. Fujiwara
5th International Symposium of Molecular Thermodynamics and Molecular Simulation, 03 Oct. 2009

cholera toxin B分泌乳酸菌を用いた ２ステップ腸管内DDSの開発
奥野隆啓; 平松征洋; 入江圭一; 宮田健; 戸田晶久; 佐藤朝光; 繪柳玲子; 新川武; 中島幸彦; 鹿志毛信広; 見明史雄
日本薬学会第129年会, 25 Mar. 2009