Haptoglobin Regulates Macrophage/Microglia-Induced Inflammation and Prevents Ischemic Brain Damage Via Binding to HMGB1

Mayuka Morimoto; Takafumi Nakano; Saki Egashira; Keiichi Irie; Kiyoshi Matsuyama; Momoka Wada; Yoshihiko Nakamura; Yutaka Shigemori; Hiroyasu Ishikura; Yuta Yamashita; Kazuhide Hayakawa; Kazunori Sano; Kenichi Mishima
JOURNAL OF THE AMERICAN HEART ASSOCIATION, Mar. 2022, 11(6), Refereed

Tyrosine 136 phosphorylation of α-synuclein aggregates in the Lewy body dementia brain: involvement of serine 129 phosphorylation by casein kinase 2.

Kazunori Sano; Yasushi Iwasaki; Yuta Yamashita; Keiichi Irie; Masato Hosokawa; Katsuya Satoh; Kenichi Mishima
Acta neuropathologica communications, 12 Nov. 2021, 9(1):182 - 182

Antithrombin gamma attenuates macrophage/microglial activation and brain damage after transient focal cerebral ischemia in mice.

Takafumi Nakano; Yoshihiko Nakamura; Keiichi Irie; Shinobu Okano; Mayuka Morimoto; Yuta Yamashita; Tomohiro Kozako; Toshinobu Hayashi; Shin-Ichiro Honda; Koichi Matsuo; Hidetoshi Kamimura; Hiroyasu Ishikura; Takashi Egawa; Kenichi Mishima
Life Sci., Jul. 2020, 252:117665 - 117665, Refereed

Characterization and pharmacokinetics evaluation of microcomposite particles of alpha lipoic acid/hydrogenated colza oil obtained in supercritical carbon dioxide.

Masathoshi Honjo; Okuraha Yasuhide; Masayoshi Yamada; Sei Higuchi; Kenji Mishima; Tanjina Sharmin; Taku Michael Aida; Takafumi Kato; Makoto Misumi; Tadashi Suetsugu; Hideaki Orii; Keiichi Irie; Kazunori Sano; Kenichi Mishima; Tomomitsu Satho; Takunori Harada
Pharm Dev Technol., Mar. 2020, 25(3):359 - 365

大麻成分の中枢効果：有用性と危険性.

三島健一; 入江圭一
薬学雑誌, Dec. 2019, 140(2):193 - 204, Refereed

EP4 receptor-associated protein regulates gluconeogenesis in the liver and is associated with hyperglycemia in diabetic mice.

Sei Higuchi; Risako Fujikawa; Masato Nakatsuji; Mika Yasui; Taichi Ikedo; Manabu Nagata; Kenji Mishima; Keiichi Irie; Michihiro Matsumoto; Masayuki Yokode; Manabu Minami
Physiol Endocrinol Metab., Mar. 2019, 316(3):E410 - E417, Refereed

Long-term treatment with thrombomodulin improves functional outcomes after cerebral Ischemia even if administration is delayed

Nakano T; Nakamura Y; Matsuyama K; Irie K; Yasumura M; Hirata Y; Yamasaki M; Misumi K; Yamashita Y; Myose T; Matsuo K; Sano K; Kamimura H; Ishikura H; Egawa T; Mishima K
Thrombosis and haemostasis, Mar. 2019, 119(3):467 - 478, Refereed

Lactobacillus plantarum induces genomic DNA-dependent and TLR9-mediated elafin secretion from Caco-2 cells.

Hiramatsu Y; Sakamoto D; Satho T; Irie K; Miake F; Maeda M; Kashige N
Asian Pacific journal of allergy and immunology, Mar. 2019, 37(1):36 - 42, Refereed

Δ9-Tetrahydrocannabinol elicited 22-kHz ultrasonic vocalization changes after air puff stimulus through CB1 receptor in adult rats.

Myose T; Shirakawa A; Irie K; Yamashita Y; Nakano T; Takase Y; Matsuo K; Satho T; Tuchihashi R; Kinjo J; Tanaka H; Morimoto S; Funada M; Sano K; Mishima K
Neurosci Lett., 10 Feb. 2019

Goreisan Prevents Brain Edema after Cerebral Ischemic Stroke by Inhibiting Aquaporin 4 Upregulation in Mice

Takafumi Nakano; Chisa Nishigami; Keiichi Irie; Yutaka Shigemori; Kazunori Sano; Yuta Yamashita; Takayuki Myose; Koji Tominaga; Koichi Matsuo; Yoshihiko Nakamura; Hiroyasu Ishikura; Hidetoshi Kamimura; Takashi Egawa; Kenichi Mishima
Journal of Stroke and Cerebrovascular Diseases, 01 Mar. 2018, 27(3):758 - 763, Refereed

Involvement of Charcot-Marie-Tooth disease gene mitofusin 2 expression in paclitaxel-induced mechanical allodynia in rats

Yuta Yamashita; Keiichi Irie; Akane Kochi; Nami Kimura; Toshinobu Hayashi; Koichi Matsuo; Takayuki Myose; Kazunori Sano; Takafumi Nakano; Yumi Takase; Yoshihiko Nakamura; Tomomitsu Satho; Kenji Mishima; Kenichi Mishima
NEUROSCIENCE LETTERS, Jul. 2017, 653:337 - 340, Refereed

Effects of Teicoplanin on the PT-INR Controlled by Warfarin in Infection Patients

Takafumi Nakano; Tomomi Nakamura; Yoshihio Nakamura; Keiichi Irie; Keisuke Sato; Kohichi Matsuo; Osamu Imakyure; Kentaro Ogata; Kenichi Mishima; Hidetoshi Kamimura
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, Jul. 2017, 137(7):909 - 916, Refereed

Activations of muscarinic M1 receptors in the anterior cingulate cortex contribute to the antinociceptive effect via GABAergic transmission

Kohei Koga; Yu Matsuzaki; Kenji Honda; Fumihiro Eto; Tomonori Furukawa; Keisuke Migita; Keiichi Irie; Kenichi Mishima; Shinya Ueno
Molecular Pain, 2017, 13:1 - 11, Refereed

Enhancement and regulation effect of myrcene on antibody response in immunization with ovalbumin and Ag85B in mice

Saori Uyeda; Tanjina Sharmin; Tomomitsu Satho; Keiichi Irie; Mineo Watanabe; Masato Hosokawa; Yukihiro Hiramatsu; Takayuki Koga; Yukihiko Nakashima; Nobuhiro Kashige; Akihisa Toda; Kenji Mishima; Fumio Miake
ASIAN PACIFIC JOURNAL OF ALLERGY AND IMMUNOLOGY, Dec. 2016, 34(4):314 - 321, Refereed

Effect of Simple Calculation Exercise on Cerebral Blood Oxygenation during a Verbal Memory Task Measured by fNIRS

Makoto Misumi; Kenji Mishima; Hideaki Orii; Tanjina Sharmin; Shinichi Tokunaga; Masashi Haraguchi; Miyuki Nakamura; Takunori Harada; Tadashi Suetsugu; Keiichi Irie; Kenichi Mishima; Tomomitsu Satho
Journal of the Institute of Industrial Applications Engineers, 25 Oct. 2016, 4(4):199 - 205, Refereed

Extraction of Isovitexin from Melinjo (Gnetum Gnemon L.) Leaves Using Mixtures of Liquid Carbon Dioxide and Ethanol

Yusraini Dian; Inayati Siregar; Kenji Mishima; Ryo Kawakami; Shota Ito; Yuuta Inoue; Tetsuya Hirota; Tanjina Sharmin; Takafumi Kato; Takunori Harada; Makoto Misumi; Hideaki Orii; Tadashi Suetsugu; Keiichi Irie; Kenichi Mishima; Kumiko Sakai; Kenji Sakai; Hirofumi Kawamura; Hilyatuz Zahroh; Nurelela; Adi Riyadahi; Lily Surayya Eka Putri; Agus Salim
International Journal of Biomass & Renewables, Oct. 2016, 5(2):23 - 30, Refereed

Gas-saturated solution process to obtain microcomposite particles of alpha lipoic acid/hydrogenated colza oil in supercritical carbon dioxide

Kenji Mishima; Masatoshi Honjo; Tanjina Sharmin; Shota Ito; Ryo Kawakami; Takafumi Kato; Makoto Misumi; Tadashi Suetsugu; Hideaki Orii; Hiroyuki Kawano; Keiichi Irie; Kazunori Sano; Kenichi Mishima; Takunori Harada; Mikio Ouchi
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, Sep. 2016, 21(6):737 - 748, Refereed

Change of teicoplanin loading dose requirement for incremental increases of systemic inflammatory response syndrome score in the setting of sepsis.

Takafumi Nakano; Yoshihiko Nakamura; Tohru Takata; Keiichi Irie; Kazunori Sano; Osamu Imakyure; Kenichi Mishima; Koujirou Futagami
Int J Clin Pharm, Aug. 2016, Refereed

Ultrasonically enhanced extraction of luteolin and apigenin from the leaves of Perilla frutescens (L.) Britt. using liquid carbon dioxide and ethanol

Hirofumi Kawamura; Kenji Mishima; Tanjina Sharmin; Shota Ito; Ryo Kawakami; Takafumi Kato; Makoto Misumi; Tadashi Suetsugu; Hideaki Orii; Hiroyuki Kawano; Keiichi Irie; Kazunori Sano; Kenichi Mishima; Takunori Harada; Salim Mustofa; Fauziyah Hasanah; Yusraini Dian Inayati Siregar; Hilyatuz Zahroh; Lily Surayya Eka Putri; Agus Salim
ULTRASONICS SONOCHEMISTRY, Mar. 2016, 29:19 - 26, Refereed

Recombinant human soluble thrombomodulin ameliorates cerebral ischemic injury through a high-mobility group box 1 inhibitory mechanism without hemorrhagic complications in mice

Yoshihiko Nakamura; Takafumi Nakano; Keiichi Irie; Kazunori Sano; Junichi Tanaka; Yuta Yamashita; Tomomitsu Satho; Koichi Matsuo; Masayuki Fujioka; Hiroyasu Ishikura; Kenichi Mishima
JOURNAL OF THE NEUROLOGICAL SCIENCES, Mar. 2016, 362:278 - 282, Refereed

Delayed treatment with ADAMTS13 ameliorates cerebral ischemic injury without hemorrhagic complication

Takafumi Nakano; Keiichi Irie; Kazuhide Hayakawa; Kazunori Sano; Yoshihiko Nakamura; Masayoshi Tanaka; Yuta Yamashita; Tomomitsu Satho; Masayuki Fujioka; Carl Muroi; Koichi Matsuo; Hiroyasu Ishikura; Kojiro Futagami; Kenichi Mishima
BRAIN RESEARCH, Oct. 2015, 1624(1624):330 - 335, Refereed

Gas-saturated solution process to obtain microcomposite particles of alpha lipoic acid/hydrogenated colza oil in supercritical carbon dioxide.

Mishima K; Honjo M; Sharmin T; Ito S; Kawakami R; Kato T; Misumi M; Suetsugu T; Orii H; Kawano H; Irie K; Sano K; Mishima K; Harada T; Ouchi M
Pharm Dev Technol., 29 May 2015, (29):1 - 12, Refereed

Liquid Carbon Dioxide Extraction of Xanthones from the Pericarps of Garcinia Mangostana Linn. Enhanced by Ultrasonic Irradiation

Kenji Mishima; Hirofumi Kawamura; Shota Ito; Yuuta Inoue; Tetsuya Hirota; Takafumi Kato; Tanjina Sharmin; Ryo Kawakami; Keiichi Irie; Kenichi Mishima; Takunori Harada; Salim Mustofa; Fauziyah Hasanah; Yusraini Dian Inayati Siregar; Lily Surayya Eka Putri; Agus Salim
SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, 2015, 22:187 - 199, Refereed

Extraction of Resveratrol from Melinjo (Gnetum gnemon L.) Seeds Using Mixtures of Liquid Carbon Dioxide and Ethanol

Kenji Mishima; Yusraini Dian Inayati Siregar; Hirofumi Kawamura; Ryo Kawakami; Shota Ito; Yuuta Inoue; Tetsuya Hirota; Takunori Harada; Takafumi Kato; Makoto Misumi; Tadashi Suetsugu; Keiichi Irie; Kenichi Mishima; Salim Mustofa; Fauziyah Hasanah; Hilyatuz Zaharo; Lily Surayya Eka Putri; Agus Salim
SOLVENT EXTRACTION RESEARCH AND DEVELOPMENT-JAPAN, 2015, 22(1):69 - 77, Refereed

Effects of Comb Tooth Cap Medicinal Mushroom, Hericium ramosum (Higher Basidiomycetes) Mycelia on DPPH Radical Scavenging Activity and Nerve Growth Factor Synthesis

Kohei Suruga; Kazunari Kadokura; Yoshihiro Sekino; Takafumi Nakano; Koichi Matsuo; Keiichi Irie; Kenichi Mishima; Makoto Yoneyama; Yasuhiro Komatsu
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS, 2015, 17(4):331 - 338, Refereed

脳血管性障害に対する血液凝固制御因子ADAMTS13の脳保護効果

中野貴文; 入江圭一; 三島健一; 二神幸次郎; 岩崎克典
臨床と研究, Nov. 2014, 91(11):127 - 127

The anti-inflammatory effects of a high-frequency oligodeoxynucleotide from the genomic DNA of Lactobacillus casei

Yukihiro Hiramatsu; Tomomitsu Satho; Mika Hyakutake; Keiichi Irie; Kenichi Mishima; Fumio Miake; Nobuhiro Kashige
INTERNATIONAL IMMUNOPHARMACOLOGY, Nov. 2014, 23(1):139 - 147, Refereed

The anti-inflammatory effects of a high-frequency oligodeoxynucleotide from the genomic DNA of Lactobacillus casei (登録用)

Yukihiro Hiramatsu; Tomomitsu Satho; Mika Hyakutake; Keiichi Irie; Kenichi Mishima; Fumio Miake; Nobuhiro Kashige
INTERNATIONAL IMMUNOPHARMACOLOGY, Nov. 2014, 23(1):139 - 147, Refereed

ヤマブシタケ子実体食品「山伏乃賜玉」のアルツハイマー病に対する薬理学的検討と臨床効果

小松靖弘; 三島健一; 入江圭一; 片岡愛子; 櫨川舞; 松尾宏一; 清水道隆; 大友英一
BIO Clinica, Jul. 2014, 29(9):102 - 108

Recombinant fusion protein of cholera toxin B subunit with YVAD secreted by Lactobacillus casei inhibits lipopolysaccharide-induced caspase-1 activation and subsequent IL-1 beta secretion in Caco-2 cells

Yukihiro Hiramatsu; Masatatsu Yamamoto; Tomomitsu Satho; Keiichi Irie; Akiko Kai; Uyeda Saori; Yuki Fukumitsu; Akihisa Toda; Takeshi Miyata; Fumio Miake; Takeshi Arakawa; Nobuhiro Kashige
BMC Biotechnology, May 2014, 14:38, Refereed

Effect of ADAMTS-13 on cerebrovascular microthrombosis and neuronal injury after experimental subarachnoid hemorrhage

C. Muroi; M. Fujioka; K. Mishima; K. Irie; Y. Fujimura; T. Nakano; J. Fandino; E. Keller; K. Iwasaki; M. Fujiwara
JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Apr. 2014, 12(4):505 - 514, Refereed

白金錯体系抗悪性腫瘍剤のオキサリプラチンによる末梢神経障害に対する加工ブシの軽減効果

MATSUO Koichi; IRIE Keiichi; HAYASHI Toshinobu; ICHIMARU Yuki; SHIRAKAWA Atsunori; HASEGAWA Kyoko; OHTSU Kaya; HARA Koyori; KURANARI Saori; YAMASHITA Ikuta; MISHIMA Ken-ichi; IWASAKI Katsunori; FUJIWARA Michihiro
Kampo & the Newest Therapy, Aug. 2013, 22(3):243 - 250

Extraction of xanthones from the pericarps of garcinia mangostana linn. with supercritical carbon dioxide and ethanol

Kenji Mishima; Ryo Kawakami; Haruo Yokota; Takunori Harada; Takafumi Kato; Keiichi Irie; Kenichi Mishima; Michihiro Fujiwara; Kiyoshi Matsuyama; Salim Mustofa; Agus Salim
Solvent Extraction Research and Development, Japan, 26 Jun. 2013, 20:79 - 89, Refereed

Expression and secretion of cholera toxin B subunit in lactobacilli

Takahiro Okuno; Nobuhiro Kashige; Tomomitsu Satho; Keiichi Irie; Yukihiro Hiramatsu; Tanjina Sharmin; Yuki Fukumitsu; Saori Uyeda; Seitaro Yamada; Tetsuya Harakuni; Takeshi Miyata; Takeshi Arakawa; Masumi Imoto; Akihisa Toda; Yukihiko Nakashima; Fumio Miake
Biological and Pharmaceutical Bulletin, Jun. 2013, 36(6):952 - 8, Refereed

Bioimaging application of highly luminescent silica-coated ZnO-nanoparticle quantum dots with biotin

Kiyoshi Matsuyama; Neil Ihsan; Keiichi Irie; Kenichi Mishima; Tetsuya Okuyama; Hiroyuki Muto
Journal of Colloid and Interface Science, 01 Jun. 2013, 399(1):19 - 25, Refereed

Pyriproxyfen enhances the Immunoglobulin G immune response in mice

Tanjina Sharmin; Tomomitsu Satho; Keiichi Irie; Mineo Watanabe; Masato Hosokawa; Yukihiro Hiramatsu; Parimal Talukder; Takahiro Okuno; Shodai Tsuruda; Saori Uyeda; Yuki Fukmits; Yukie Tamura; Yukihiko Nakashima; Masumi Imoto; Akihisa Toda; Nobuhiro Kashige; Fumio Miake
Microbiology and Immunology, Apr. 2013, 57(4):316 - 22, Refereed

Differences in TLR9-dependent inhibitory effects of H2O2-induced IL-8 secretion and NF-kappa B/I kappa B-alpha system activation by genomic DNA from five Lactobacillus species

Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Shota Shiimura; Takahiro Okuno; Tanjina Sharmin; Saori Uyeda; Yuki Fukumitsu; Yukihiko Nakashima; Fumio Miake; Nobuhiro Kashige
MICROBES AND INFECTION, Feb. 2013, 15(2):96 - 104, Refereed

Ameliorative Effects of Telmisartan on the Inflammatory Response and Impaired Spatial Memory in a Rat Model of Alzheimer's Disease Incorporating Additional Cerebrovascular Disease Factors

Taro Shindo; Kotaro Takasaki; Kanako Uchida; Rika Onimura; Kaori Kubota; Naoki Uchida; Keiichi Irie; Shutaro Katsurabayashi; Kenichi Mishima; Ryoji Nishimura; Michihiro Fujiwara; Katsunori Iwasaki
BIOLOGICAL & PHARMACEUTICAL BULLETIN, Dec. 2012, 35(12):2141 - 2147, Refereed

Hypothalamic 2-arachidonoylglycerol regulates multistage process of high-fat diet preferences.

Higuchi S; Irie K; Yamaguchi R; Katsuki M; Araki M; Ohji M; Hayakawa K; Mishima S; Akitake Y; Matsuyama K; Mishima K; Mishima K; Iwasaki K; Fujiwara M
PLoS One, Jun. 2012, 7(6), Refereed

Elevation of dopamine level reduces host-seeking activity in the adult female mosquito Aedes albopictus

Yuki Fukumitsu; Keiichi Irie; Tomomitsu Satho; Hitoshi Aonuma; Hamady Dieng; Abu Hassan Ahmad; Yukihiko Nakashima; Kenichi Mishima; Nobuhiro Kashige; Fumio Miake
PARASITES & VECTORS, May 2012, 5(1):92, Refereed

Transparent polymeric hybrid film of ZnO nanoparticle quantum dots and PMMA with high luminescence and tunable emission color

Kiyoshi Matsuyama; Kenji Mishima; Takafumi Kato; Keiichi Irie; Kenichi Mishima
JOURNAL OF COLLOID AND INTERFACE SCIENCE, Feb. 2012, 367:171 - 177, Refereed

ADAMTS13 gene deletion enhances plasma high-mobility group box1 elevation and neuroinflammation in brain ischemia-reperfusion injury

Fujioka M; Nakano T; Hayakawa K; Irie K; Akitake Y; Sakamoto Y; Mishima K; Muroi C; Yonekawa Y; Banno F; Kokame K; Miyata T; Nishio K; Okuchi K; Iwasaki K; Fujiwara M; Siesjö BK
Neurol Sci, Jan. 2012, 33(5):1107 - 1115, Refereed

ヤマブシタケ子実体」食品によるマウスの脳梗塞改善作用

片岡愛子; 櫨川 舞; 入江圭一; 秋武義治; 中野貴文; 早川和秀; 三島健一; 三島健司; 吉田 都; 藤岡稔大; 内田享弘; 小松靖弘; 岩崎克典; 藤原道弘
機能性食品と薬理栄養, Jul. 2011, 5(6):281 - 287, Refereed

Measuement of cerebral blood oxygenation during a verbal memory task by means of fNIRS

Kenji Mishima; Kiyoshi Matsuyama; Takafumi Kato; Tadashi Suetsugu; Shigeto Aramaki; Hiroaki Tanaka; Yasuki Higaki; Soichi Ando; Keiichi Irie; Sei Higuchi; Yoshiharu Akitake; Kenichi Mishima; Michihiro Fujiwara
2011 IEEE REGION 10 CONFERENCE TENCON 2011, 2011, :1212 - 1215, Refereed

Increment of hypothalamic 2-arachidonoylglycerol induces the preference for a high-fat diet via activation of cannabinoid 1 receptors

Sei Higuchi; Makiko Ohji; Maiko Araki; Riyo Furuta; Mai Katsuki; Ryuji Yamaguchi; Yoshiharu Akitake; Kiyoshi Matsuyama; Keiichi Irie; Kenji Mishima; Kenichi Mishima; Katsunori Iwasaki; Michihiro Fujiwara
BEHAVIOURAL BRAIN RESEARCH, Jan. 2011, 216(1):477 - 480, Refereed

Trace metal zinc stimulates secretion of antimicrobial peptide LL-37 from Caco-2 cells through ERK and p38 MAP kinase

Parimal Talukder; Tomomitsu Satho; Keiichi Irie; Tanjina Sharmin; Dieng Hamady; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
INTERNATIONAL IMMUNOPHARMACOLOGY, Jan. 2011, 11(1):141 - 144, Refereed

Sex differences in the benefits of rehabilitative training during adolescence following neonatal hypoxia-ischemia in rats

Masahiro Tsuji; Naoya Aoo; Kazuhiro Harada; Yuya Sakamoto; Yoshiharu Akitake; Keiichi Irie; Kenichi Mishima; Tomoaki Ikeda; Michihiro Fujiwara
EXPERIMENTAL NEUROLOGY, Dec. 2010, 226(2):285 - 292, Refereed

マウスを用いた駆瘀血丹参製剤の脳虚血性疾患に対する予防効果

ENOKI Makiko; KANEKO Tomohiro; IRIE Keiichi; AKITAKE Yoshiharu; HAYAKAWA Kazuhide; NAGATO Mami; MISHIMA Ken-ichi; MISHIMA Kenji; OKAMOTO Takuya; KAMIMURA Hidetoshi; IWASAKI Katsunori; FUJIWARA Michihiro
漢方と最新治療, Aug. 2010, 19(3):251 - 258, Refereed

Neuroprotective Effect of Repeated Treatment with Hericium Erinaceum in Mice Subjected to Middle Cerebral Artery Occlusion.

Hazekawa M; Kataoka A; Hayakawa K; Uchimasu T; Furuta R; Irie K; Akitake Y; Yoshida M; Fujioka T; Egashira N; Oishi R; Mishima K; Mishima K; Uchida T; Iwasaki K; Fujiwara M
J Health Science, Jun. 2010, 56(3):296 - 303, Refereed

Inhibition of reactive astrocytes with fluorocitrate retards neurovascular remodeling and recovery after focal cerebral ischemia in mice

Kazuhide Hayakawa; Takafumi Nakano; Keiichi Irie; Sei Higuchi; Masayuki Fujioka; Kensuke Orito; Katsunori Iwasaki; Guang Jin; Eng H. Lo; Kenichi Mishima; Michihiro Fujiwara
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, Apr. 2010, 30(4):871 - 882, Refereed

Ameliorating effects of Kangen-karyu on neuronal damage in rats subjected to repeated cerebral ischemia

Fengling Pu; Tomohiro Kaneko; Makiko Enoki; Keiichi Irie; Takuya Okamoto; Yasuo Sei; Nobuaki Egashira; Ryozo Oishi; Kenichi Mishima; Hidetoshi Kamimura; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF NATURAL MEDICINES, Apr. 2010, 64(2):167 - 174, Refereed

ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion

Masayuki Fujioka; Kazuhide Hayakawa; Kenichi Mishima; Ai Kunizawa; Keiichi Irie; Sei Higuchi; Takafumi Nakano; Carl Muroi; Hidetada Fukushima; Mitsuhiko Sugimoto; Fumiaki Banno; Koichi Kokame; Toshiyuki Miyata; Michihiro Fujiwara; Kazuo Okuchi; Kenji Nishio
BLOOD, Feb. 2010, 115(8):1650 - 1653, Refereed

The cannabinoid 1-receptor silent antagonist O-2050 attenuates preference for high-fat diet and activated astrocytes in mice.

Higuchi S; Irie K; Mishima S; Araki M; Ohji M; Shirakawa A; Akitake Y; Matsuyama K; Mishima K; Mishima K; Iwasaki K; Fujiwara M
J Pharmcol Sci, Feb. 2010, 112(3):369 - 372, Refereed

Reducing acyl migration during purification of 2-arachidonoylglycerol from biological samples before gas chromatography mass spectrometry analysis

analytical sciences, 2010, 26(11), Refereed

Delta(9)-tetrahydrocannabinol Enhances an Increase of Plasma Corticosterone Levels Induced by Forced Swim-Stress

Kazunori Sano; Emi Koushi; Keiichi Irie; Sei Higuchi; Ryota Tsuchihashi; Junei Kinjo; Nobuaki Egashira; Ryozo Oishi; Naoki Uchida; Hiroshi Nagai; Ryoji Nishimura; Hiroyuki Tanaka; Satoshi Morimoto; Kenichi Mishima; Katsunori Iwasaki; Michihiro Fujiwara
BIOLOGICAL & PHARMACEUTICAL BULLETIN, Dec. 2009, 32(12):2065 - 2067, Refereed

Therapeutic Time Window of Cannabidiol Treatment on Delayed Ischemic Damage via High-Mobility Group Box1-Inhibiting Mechanism

Kazuhide Hayakawa; Keiichi Irie; Kazunori Sano; Takuya Watanabe; Sei Higuchi; Makiko Enoki; Takafumi Nakano; Kazuhiko Harada; Shin Ishikane; Tomoaki Ikeda; Masayuki Fujioka; Kensuke Orito; Katsunori Iwasaki; Kenichi Mishima; Michihiro Fujiwara
BIOLOGICAL & PHARMACEUTICAL BULLETIN, Sep. 2009, 32(9):1538 - 1544

Extraction of Silymarins from Milk Thistle Seeds Using Supercritical Carbon Dioxide with Methanol

M. HONJO; K MISHIMA; K. MATSUYAMA; H.SEKIGUCHI; S.ANDO; K.RIE; K.MISHIMA; M.FUJIWARA
Solvent Extraction Research and Development, Japan, Apr. 2009, 16:105 - 114, Refereed

Neuroprotective Effects of Kangen-karyu on Spatial Memory Impairment in an 8-Arm Radial Maze and Neuronal Death in the Hippocampal CA1 Region Induced by Repeated Cerebral Ischemia in Rats

Fengling Pu; Kyoko Motohashi; Tomohiro Kaneko; Yurika Tanaka; Naorni Manome; Keiichi Irie; Jirou Takata; Nobuaki Egashira; Ryozo Oishi; Takuya Okamoto; Yasuo Sei; Takako Yokozawa; Kenichi Mishima; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, Mar. 2009, 109(3):424 - 430, Refereed

Cannabidiol prevents a post-ischemic injury progressively induced by cerebral ischemia via a high-mobility group box1-inhibiting mechanism

Kazuhide Hayakawa; Kenichi Mishima; Keiichi Irie; Mai Hazekawa; Shohei Mishima; Masayuki Fujioka; Kensuke Orito; Nobuaki Egashira; Shutaro Katsurabayashi; Kotaro Takasaki; Katsunori Iwasaki; Michihiro Fujiwara
NEUROPHARMACOLOGY, Dec. 2008, 55(8):1280 - 1286, Refereed

Delayed treatment with minocycline improves neurological impairment via activated microglia expressing high-mobility group box1 inhibiting mechanism

Hayakawa K; Mishima K; Nozako M; Irie K; Hazekawa M; Mishima S; Fujioka M; Orito K; Egashira N; Iwasaki K; Fujiwara M
Stroke, 2008, 39(3):951 - 958

Cannabidiol potentiates pharmacological effects of Delta(9)-tetrahydrocannabinol via CB1 receptor-dependent mechanism

Kazuhide Hayakawa; Kenichi Mishima; Mai Hazekawa; Kazunori Sano; Keiichi Irie; Kensuke Orito; Takashi Egawa; Yoshihisa Kitamura; Naoki Uchida; Ryoji Nishimura; Nobuaki Egashira; Katsunori Iwasaki; Michihiro Fujiwara
BRAIN RESEARCH, Jan. 2008, 1188:157 - 164, Refereed

Delta(9)-tetrahydrocannabinol-induced catalepsy-like immobilization is mediated by decreased 5-HT neurotransmission in the nucleus accumbens due to the action of glutamate-containing neurons

K. Sano; K. Mishima; E. Koushi; K. Orito; N. Egashira; K. Irie; K. Takasaki; S. Katsurabayashi; K. Iwasaki; N. Uchida; T. Egawa; Y. Kitamura; R. Nishimura; M. Fujiwara
NEUROSCIENCE, Jan. 2008, 151(2):320 - 328, Refereed

Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism

Kazuhide Hayakawa; Kenichi Mishima; Masanori Nozako; Mai Hazekawa; Keiichi Irie; Masayuki Fujioka; Kensuke Orito; Kohji Abe; Nobuyoshi Hasebe; Nobuaki Egashira; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF NEUROCHEMISTRY, Sep. 2007, 102(5):1488 - 1496, Refereed

Neuroprotective effects of quercetin and rutin on spatial memory impairment in an 8-arm radial maze task and neuronal death induced by repeated cerebral ischemia in rats

Fengling Pu; Kenichi Mishima; Keiichi Irie; Kyouko Motohashi; Yurika Tanaka; Kensuke Orito; Takashi Egawa; Yoshihisa Kitamura; Nobuaki Egashira; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, Aug. 2007, 104(4):329 - 334, Refereed

Down regulation of the L-type Ca2+ channel, GRK2, and phosphorylated phospholamban: protective mechanisms for the denervated failing heart.

Yatani A; Shen YT; Yan L; Chen W; Kim SJ; Sano K; Irie K; Vatner SF; Vatner DE
J Mol Cell Cardiol, Mar. 2006, 40(5):619 - 628, Refereed

Dual effects of mesenteric lymph isolated from rats with burn injury on contractile function in rat ventricular myocytes.

Yatani A; Xu DZ; Irie K; Sano K; Jidarian A; Vatner SF; Deitch EA
Am J Physiol Heart Circ Physiol, Feb. 2006, 290(2):H778 - H785, Refereed

Cardiac-specific overexpression of AT1 receptor mutant lacking G(alpha)q/G(alpha)i coupling causes hypertrophy and bradycardia in transgenic mice

PY Zhai; M Yamamoto; J Galeotti; J Liu; M Masurekar; J Thaisz; K Irie; E Holle; XZ Yu; S Kupershmidt; DM Roden; T Wagner; A Yatani; DE Vatner; SF Vatner; J Sadoshima
JOURNAL OF CLINICAL INVESTIGATION, Nov. 2005, 115(11):3045 - 3056, Refereed

RhoA GTPase regulates L-type Ca2+ currents in cardiac myocytes

A Yatani; K Irie; T Otani; M Abdellatif; L Wei
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, Feb. 2005, 288(2):H650 - H659, Refereed

The differential effects of Buckwheat extract and KuDingcha extract on neuronal damage in cultured hippocampal neurons and spatial memory impairment induced by scopolamine in an 8-arm radial maze.

Pu F; Mishima K; Irie K; Egashira N; Ishibashi D; Matsumoto Y; Ikeda T; Iwasaki K; Fujii H; Kosuna K; Fujiwara M
J Health Science, 2005, 51(6):636 - 644

Post-ischemic treatment with Toki-shakuyaku-san (Tang-Gui-Shao-Yao-San) prevents the impairment of spatial memory induced by repeated cerebral ischemia in rats

FL Pu; K Mishima; N Egashira; Y Akiyoshi; AX Liu; K Sano; K Irie; D Ishibashi; Hatip-Al-Khatib, I; K Iwasaki; K Kurauchi; K Iwasaki; M Fujiwara
AMERICAN JOURNAL OF CHINESE MEDICINE, 2005, 33(3):475 - 489, Refereed

Protective effect of buckwheat polyphenols against long-lasting impairment of spatial memory associated with hippocampal neuronal damage in rats subjected to repeated cerebral ischemia

FL Pu; K Mishima; N Egashira; K Iwasaki; T Kaneko; T Uchida; K Irie; D Ishibashi; H Fujii; K Kosuna; M Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, Apr. 2004, 94(4):393 - 402, Refereed

Insights into cardioprotection obtained from study of cellular Ca2+ handling in myocardium of true hibernating mammals.

Yatani A; Kim SJ; Kudej RK; Wang Q; Depre C; Irie K; Kranias EG; Vatner SF; Vatner DE
Am J Physiol Heart Circ Physiol, Feb. 2004, 286(6):H2219 - H2228, Refereed

Protection by buckwheat polyphenols of cell death induced by glutamate and kainate in cultured hippocampal neurons.

Pu F; Mishima K; Irie K; Egashira N; Iwasaki K; Ikeda T; Fujii H; Kosuna K; Fujiwara M
J Trad Med, 2004, 21:143 - 146

Non-NMDA mechanism in the inhibition of cellular apoptosis and memory impairment induced by repeated ischemia in rats

K Iwasaki; EH Chung; E Egashira; Hatip-Al-Khatib, I; K Mishima; T Egawa; K Irie; M Fujiwara
BRAIN RESEARCH, Jan. 2004, 995(1):131 - 139, Refereed

Effect of nilvadipine on the cerebral ischemia-induced impairment of spatial memory and hippocampal apoptosis in rats

K Iwasaki; K Mishima; N Egashira; IH Al-Khatib; D Ishibashi; K Irie; H Kobayashi; T Egawa; M Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, Oct. 2003, 93(2):188 - 196, Refereed

Neurally-mediated increase in calcineurin activity regulates cardiac contractile function in absence of hypertrophy

JA Li; A Yatani; SJ Kim; G Takagi; K Irie; QH Zhang; Karoor, V; CL Hong; GP Yang; J Sadoshima; C Depre; DE Vatner; MJ West; SF Vatner
CARDIOVASCULAR RESEARCH, Sep. 2003, 59(3):649 - 657, Refereed

Involvement of bcl-family expression in the spatial memory impairment induced by repeated ischemia

K Irie; K Mishima; D Ishibashi; N Egashira; K Iwasaki; M Fujiwara
LIFE SCIENCES, Dec. 2002, 72(4-5):621 - 629

Hypoxia enhances beta-amyloid-induced apoptosis in rat cultured hippocampal neurons

N Egashira; K Iwasaki; M Ishibashi; Hatip-Al-Khatib, I; B Wolozin; K Mishima; K Irie; M Fujiwara
JAPANESE JOURNAL OF PHARMACOLOGY, Dec. 2002, 90(4):321 - 327, Refereed

脳梗塞モデルマウスにおけるSerum Amyloid A(SAA)の動態

江頭早紀; 真崎有裕子; 向井梨恵; 中野貴文; 中野貴文; 細川雅人; 亀谷富由樹; 入江圭一; 佐藤朝光; 山下郁太; 佐野和憲; 三島健一
日本薬学会年会要旨集(Web), 2023, 143rd

脳虚血‐再灌流障害モデルマウスを用いた脳浮腫に対する五苓散の効果

西上知佐; 中野貴文; 中野貴文; 水野寧子; 入江圭一; 山下郁太; 明瀬孝之; 高瀬友美; 藤岡政行; 佐藤朝光; 佐野和憲
和漢医薬学会学術大会要旨集, Aug. 2016, 33rd:95 - 95

血小板凝集因子vWF切断酵素ADAMTS13とそのマルチドメインによる脳保護効果の解明

中野貴文; 入江圭一
福岡大学産学官連携研究機関加齢脳科学研究所 2013年度研究成果報告書：37-49、2014, Mar. 2014, :p37 - 74

Involvement of trombospondin 1 on cerebroprotective effect of ADAMTS13 in brain injury after transient focal cerebral ischemia

Masayoshi Tanaka; Keiichi Irie; Takafumi Nakano; Kaori Kubota; Shutaro Katsurabayashi; Kotaro Takasaki; Koujirou Futagami; Kenichi Mishima; Katsunori Iwasaki
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2014, 124:148P - 148P

ミルセンによるアジュバント効果とその作用機序

末延竜哉; SHARMIN Tanjina; 佐藤朝光; 入江圭一; 細川雅人; 平松征洋; 上田紗織; 中島幸彦; 鹿志毛信広; 見明史雄; 渡邉峰雄; 福光由起; 井本真澄; 戸田晶久
J Tradit Med, 29 Jul. 2013, 30(Suppl.):95 - 95

myrceneによるマウスのIgGの産生誘導とその機序

大森果奈; SHARMIN Tanjina; 佐藤朝光; 入江圭一; 渡邉峰雄; 細川雅人; 平松征洋; 上田沙織; 福光由起; 中島幸彦; 井本真澄; 戸田晶久; 鹿志毛信広; 見明史雄
日本薬学会年会要旨集(CD-ROM), Mar. 2013, 133年会(3):141 - 141

Role of astrocyte in the hypothalamus on the high-fat diets preference in mice

Mai Katsuki; Sei Higuchi; Ryuji Yamaguchi; Maiko Araki; Makiko Ohji; Riyo Furuta; Kohei Kimoto; Yuya Sakamoto; Keiichi Irie; Kiyoshi Matsuyama; Kenji Mishima; Shyutaro Katsurabayashi; Kotaro Takasaki; Kaori Kubota; Kenichi Mishima; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2012, 118:184P - 184P

Cholera Toxin Bと乳酸菌を融合した2ステップ腸管内DDSの開発

奥野隆啓; 平松征洋; 上田紗織; 浦田朋子; 入江圭一; 宮田健; 戸田晶久; 佐藤朝光; 繪柳玲子; 新川武; 中島幸彦; 鹿志毛信広; 見明史雄
日本薬学会年会要旨集, 05 Mar. 2011, 131st(3):215

Fluorocitrate; an inhibitor of astrocytic metabolism attenuates the preference induced by 2-week intake of high-fat diets

Mai Katsuki; Sei Higuchi; Ryuji Yamaguchi; Maiko Araki; Makiko Ohji; Riyo Furuta; Keiichi Irie; Kiyoshi Matsuyama; Kenji Mishima; Kenichi Mishima; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011, 115:114P - 114P

Pathophysiological role of ADAMTS13 in ischemic injury after transient focal cerebral ischemia

Takafumi Nakano; Kazuhide Hayakawa; Masayuki Fujioka; Keiichi Irie; Sei Higuchi; Yoshiharu Akitake; Keisuke Kawasaki; Masayuki Tamano; Kenichi Mishima; Katunori Iwasaki; Michihiro Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011, 115:76P - 76P

Endocannabinoids regulates preference for high-fat diet

Sei Higuchi; Kenichi Mishima; Maiko Araki; Makiko Ohji; Keiichi Irie; Kenji Mishima; Syutaro Katsurabayashi; Kotaro Takasaki; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010, 112:69P - 69P

Reactive astrocytes are involved in gender difference in slowly progressive brain damage induced by hypoxic-ischemic injury

Yuya Sakamoto; Shin Ishikane; Kazuhiko Harada; Kenichi Mishima; Keiichi Irie; Sei Higuchi; Atsunori Shirakawa; Yoko Miyazaki; Tomoaki Ikeda; Shutaro Katsurabayashi; Kotaro Takasaki; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010, 112:189P - 189P

CTB分泌乳酸菌を用いた2ステップ腸管内DDSの開発

宮田健; 奥野隆啓; 平松征洋; 入江圭一; 戸田昌久; 繪柳玲子; 新川武; 中島幸彦; 鹿志毛信広; 見明史雄
日本熱帯医学会大会プログラム抄録集, Oct. 2009, 50th:62

cholera toxin B分泌乳酸菌を用いた2ステップ腸管内DDSの開発

奥野隆啓; 平松征洋; 入江圭一; 宮田健; 戸田晶久; 佐藤朝光; 繪柳玲子; 新川武; 中島幸彦; 鹿志毛信広; 見明史雄
日本薬学会年会要旨集, 05 Mar. 2009, 129th(3):172

The preference for high-fat diets is involved in the cannabinoid receptors on astrocytes in mice

Sei Higuchi; Kenichi Mishima; Shohei Mishima; Kazuhide Hayakawa; Keiichi Irie; Shutaro Katsurabayashi; Kotaro Takasaki; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, 109:64P - 64P

A new behavioral method for evaluating irritable behavior using ultrasonic vocalizations in rat

Yusuke Yamada; Kenichi Mishima; Keiichi Irie; Kazunori Sano; Syutaro Katsurabayashi; Kotaro Takasaki; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, 109:201P - 201P

Neuroprotective effects of Hericium erinaceum against cerebral ischemia in mice

Mai Hazekavva; Kenichi Mishima; Kazuhide Hayakawa; Keiichi Irie; Miyako Yoshida; Toshihiro Fujioka; Syutaro Katsurabayashi; Kotaro Takasaki; Katsunori Iwasaki
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2008, 106:180P - 180P

高脂肪食による脂肪嗜好性形成における脳内カンナビノイドシステムの関与

三島健一; 三嶋翔平; 樋口聖; 田中由理香; 早川和秀; 入江圭一; 内田直樹; 西村良二; 岩崎克典; 藤原道弘
財団法人医科学応用研究財団助成金，生活習慣病における医学，薬学の萌芽的研究, Apr. 2007, :350 - 355

Delayed treatment with cannabidiol has a cerebroprotective action through inhibition of myeloperoxidase

Kazuhide Hayakawa; Kenichi Mishima; Keiichi Irie; Mai Hazekawa; Nobuaki Egashira; Katsunori Iwasaki; Michihiro Fujiwara
JOURNAL OF PHARMACOLOGICAL SCIENCES, 2007, 103:60P - 60P

繰り返し脳虚血による空間認知障害とAMPA受容体サブファミリーならびにアポトーシス関連遺伝子発現の経時変化

石橋大輔; 入江圭一; 岩崎克典; 三島健一; 藤原道弘
日本薬理学雑誌, 2000, 115(3):72, Refereed

Long-term treatment with recombinant human soluble thrombomodulin improves ischemic brain damage via regulating systemic HMGB1 levels in mice

Nakano T; Nakamura Y; Irie K; Yamashita Y; Myose T; Takase Y; Matsuo K; Kamimura H; Ishikura H; Sano K; Egawa T; Mishima K
Neuroscience 2018, 05 Nov. 2018, Society of Neuroscience

脳虚血-再灌流障害モデルを用いた脳浮腫に対する五苓散の効果

IRIE Keiichi; SATHO Tomomitsu
第33回和漢医薬学会学術大会, 28 Aug. 2016

Δ9-Tetrahydrocannabinol とMethamphetamine が誘発するラットの超音波発声の比較

MYOSE Takayuki; IRIE Keiichi; YAMASHITA Yuta; TEORAMAE Yuki; HIRANO Mari; NAKASHIMA Arisa; TANAKA Marino; TSUTIHASHI Ryota; KINJO Junei; SATHO Tomomitsu; SANO Kazunori; HONDA Kenji; MISHIMA Kenichi
日本薬学会第136年会, 29 Mar. 2016

オキサリプラチン誘発性末梢神経障害ラットにおける神経変性疾患Amyotrophic-Lateral-Screlosis原因遺伝子の動態

HIRAYAMA Minako; YAMASHITA Yuta; IRIE Keiichi; MYOSE Takayuki; NAKANO Takafumi; TAKASE Yumi; HARA Koyomi; IWAHASHI Risa; HYAKUTAKE Mika; HAYASHI Nobuteru; MATSUO Koichi; SATHO Tomomitsu; MISHIMA Kenji; SANO Kazunori; HONDA Kenji; MISHIMA Kenichi
日本薬学会第136年会, 29 Mar. 2016

がん化学療法に伴う末梢神経障害におけるCharcot-Marie-Tooth病原因遺伝子の関与

幸地茜; 山下郁太; 入江圭一; 明瀬孝之; 中野貴文; 高瀬友美; 原暦; 岩橋理紗; 百武美香; 林稔展; 松尾宏一; 佐藤朝光; 三島健司; 佐野和憲; 本多健治; 三島健一
日本臨床腫瘍薬学会学術大会2016, 13 Mar. 2016

TNFαは糖尿病マウスにおいて機械刺激性疼痛過敏に関与する

衛藤史博; 本多健治; 東翔子; 浅田歩; 入江圭一; 右田啓介; 三島健一
第89回日本薬理学会年会, Mar. 2016

ヒトスジシマカマイクロアレイを用いた宿主探索行動を制御する遺伝子の調査

福光由起; 佐藤朝光; 入江圭一; 上田紗織; 百武美香; 弟子丸正伸; 中島幸彦; 鹿志毛信広; 見明史雄
日本昆虫学会第76回大会 / 第60回日本応用動物昆虫学会大会 合同大会, Mar. 2016

ヒトスジシマカ白眼変異体の性質について

奥田晶子; 福光由起; 米村敦子; 村上義哉; 鹿志毛信広; 見明史雄; 佐藤朝光; 中島幸彦; 入江圭一
日本薬学会第136年会, Mar. 2016

白金系抗がん剤オキサリプラチンとシュウ酸がCharcot-Marie-Tooth病原因遺伝子に与える影響

山下郁太; 寺岡里織; 入江圭一; 岩橋理紗; 吉武麻耶; 明瀬孝之; 原暦; 百武美香; 市丸優希; 林稔展; 松尾宏一; 佐藤朝光; 三島健司; 岩崎克典; 三島健一
第31回日本薬学会九州支部会, 06 Dec. 2014

Influence of oral administration of mosquito isolated enterococcus bacteria to dextran sodium sultate induced murine colitis

Mika Hyakutake; Tomomitsu Satho; Tomomi Nakamura; Keiichi Irie; Yukihiro Hiramatsu; Saori Uyeda; Yuki Fukumitsu; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
Joint International Tropical Medicine Meeting 2014, 02 Dec. 2014

ティーエスワン誘発性食欲不振モデルラットの作製と解析

岩橋理紗; 山下郁太; 入江圭一; 寺岡里織; 吉武摩耶; 中野貴文; 林稔展; 佐藤朝光; 松尾宏一; 岩崎克典; 三島健一
第52回 日本癌治療学会学術集会, 28 Aug. 2014

オキサリプラチン誘発性末梢神経障害ラットのCharcot-Marie-Tooth病原因遺伝子の動態

寺岡里織; 入江圭一; 山下郁太; 岩橋理紗; 吉武摩耶; 明瀬孝之; 原暦; 百武美香; 市丸優希; 林稔展; 松尾宏一; 佐藤朝光; 三島健司; 岩崎克典; 三島健一
The 52nd Annual Meeting of Japan Society of Clinical Oncology, 28 Aug. 2014

ヒトスジシマカにおけるドパミンレセプターの同定

Y. Fukumitsu; K. Irie; T. Satho; S. Uyeda; Nakashima; N. Kashige; F. Miake
2014 ICN / JSCPB, 29 Jul. 2014

蚊の中腸から単離したEnterococcus属乳酸菌の新種提案

Saori Uyeda; Tomomitsu Satho; Keiichi Irie; Yukihiro Hiramatsu; Yuki Fukumitsu; Yukiko Okuyama; Manami Fukuda; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
Japan Society forLactic Acid Bacteria 2014, 17 Jul. 2014

オクトパミン量の変化がヒトスジシマカ雌の宿主探索行動へ与える影響

Y. Fukumitsu; A. Yonemura; K. Irie; T. Satho; S. Uyeda; Y. Hiramatsu; Y. Nakashima; K. Mishima; N. Kashige; F. Miake
Seventh International Symposium on Molecular Insect Science, 14 Jul. 2014

クルマエビ腸管由来乳酸菌のヒト結腸癌由来Caco-2細胞における 抗菌ペプチド発現誘導作用

梶原由紀; 平松征洋; 佐藤朝光; 宇高彩奈; 椎村翔太; 入江圭一; 上田紗織; 前田稔; 中島幸彦; 鹿志毛信広; 見明史雄
The 134th Annual Meeting of the Pharmaceutical Society of Japan, 28 Mar. 2014

脳梗塞における多機能サイトカインであるOncostatin M受容体の発現変化

Yuka Oishi; Keiichi Irie; Takafumi Nakano; Yuri Narazaki; Masaaki Tanaka; Tomomitsu Satho; Kojiro Futagami; kenichi Mishima; Katunori Iwasaki
The 134th Annual Meeting of the Pharmaceutical Society of Japan, 28 Mar. 2014

蚊から単離されたEneterococcus属菌の抗生物質感受性

Yukiko Okuyama; Yukihiko Nakashima; Manami Fukuda; Tomomitsu Satho; Keiichi Irie; Yukihiro Hiramatsu; Saori Uyeda; Yuki Fukumitsu; Nobuhiro Kashige; Fumio Miake
The 134th Annual Meeting of the Pharmaceutical Society of Japan, 28 Mar. 2014

Identification of Enterococcus Bacteria isolated from mosquito

Saori Uyeda; Tomomitsu Satho; Keiichi Irie; Yukihiro Hiramatsu; Yuki Fukumitsu; Yukiko Okuyama; Manami Fukuda; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
Tropical Medicine Meeting 2013, 11 Dec. 2013

乳酸菌由来DNAの腸管における抗炎症作用

Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Mika Hyakutake; Fumio Miake; Nobuhiro kashige
The 30th Annual Meeting of the Pharmaceutical Society of Japan, Kyushu Branch, 07 Dec. 2013

脂肪嗜好性に対する高脂肪食摂取期間が及ぼすカンナビノイドシステムの変化

Yuta Yamashita; Keiichi Irie; Ryuji Yamashita; Sei Higuchi; Takafumi Nakano; Toshinobu Hayasi; Koichi, Matsuo; Tomomitsu Satho; Kiyoshi Matsuyama; Kenji Mishima; Shutaro Katsurabayashi; Kaori Kubota; Kotaro Takasaki; Kenichi Mishima; Katsunori Iwasaki
The 66th Annual Meeting of the Japanese Pharmacological Society, West-South Branch, 16 Nov. 2013

マウスにおけるDSS誘導性大腸炎の病態とTREM-1/TREM-2の発現量比の一致

Saori Egawa; Mika Hyakutake; Tomomi Nakamura; Yukihiro Hiramatsu; Saori Ueda; Keiichi Irie; Tomomitsu Satho; Yukihiko Nakashima; Kenichi Mishima; Nobuhiro Kashige; Fumio Miake
The 86th Annual Meeting of the Japanese Biochemical Society, 11 Sep. 2013

ミルセンによるアジュバント効果とその作用機序

末延竜哉; 大森果奈; Tanjina Sharmin; 佐藤朝光; 入江圭一; 渡邉峰雄; 細川雅人; 平松征洋; 上田沙織; 福光由起; 中島幸彦; 井本真澄; 戸田晶久; 鹿志毛信広; 見明史雄
The 30th Annual Meeting of Medical and Pharmaceutical Society for WAKAN-YAKU, 31 Aug. 2013

Oligodeoxynucleotide 5'-TTTTGCCG-3' from Lactobacillus casei inhibits intestinal inflammation

Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Shota Shiimura; Yukihiko Nakashima; Fumio Miake; Nick Carpino; Nobuhiro Kashige
World Biotechnology Congress 2013, 04 Jun. 2013

myrceneによるマウスのIgGの産生誘導とその機序

Kana Oomori; Tanjina Sharmin; Tomomitsu Satho; Keiichi Irie; Mineo Watanabe; Masato Hosokawa; Yukihiro Hiramasu; Saori Uyeda; Yuki fukumitsu; Yukihiko Nakashima; Akihisa Toda; Nobuhiro Kashige; Fumio Miake
The 133th Annual Meeting of the Pharmaceutical Society of Japan, 30 Mar. 2013

DSS誘発マウス大腸炎における雌雄差

Mika Hyakutake; Yukie Tamura; Saori Egawa; Keiichi Irie; Tomomitsu Satho; Yukihiro Hiramatsu; Saori Ueda; Yuki, Fukumitsu; Yukihiko, Nakashima; Kenichi Mishima; Michihiro, Fujiwara; Nobuhiro Kashige; Fumio Miake
日本薬学会第133年会, 27 Mar. 2013

Lactobacillus caseiのゲノムDNAに含まれる抗炎症作用を持つオリゴデオキシヌクレオチドの特定と作用機構の解明

Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Shouta Shiimura; Yukihiko Nakashima; Fumio Miake; Nobuhiro Kashige
Annual Meeting of Japan Society for Bioscence, Biotechnology, and Agrochemistry 2013, 25 Mar. 2013

A decrease of host-seeking behavior in virgin female appears without elevation of dopamine levels in the adult mosquito Aede albopictus

Yuki Fukmits; Keiichi Irie; Tomomitsu Satho; Yukihiko Nakashima; Kenichi Mishima; Nobuhiro Kashige; Fumio Miake
Joint International Tropical Medicine Meeting 2012, 12 Dec. 2012

ヒト結腸癌由来Caco-2細胞における炎症誘発時のProgranulin発現と分泌

Ayana Utaka; Yukihiro Hiramatsu; Tomomitsu Satho; Shota Shiimura; Keiichi Irie; Ayumi Furukawa; Kenichi Mishima; Michihiro Fujiwara; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
The 29th Annual Meeting of the Pharmaceutical Society of Japan, Kyushu Branch, 08 Dec. 2012

乳酸菌ゲノムDNA由来の抗炎症作用を持つオリゴデオキシヌクレオチドの特定

Shota Shiimura; Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Ayana Utaka; Saori Uyeda; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
The 29th Annual Meeting of the Pharmaceutical Society of Japan, Kyushu Branch, 08 Dec. 2012

The possibility of Pyriproxyfen as an adjuvant to promote Th1 immune responses

Tanjina Sharmin; Tomomitsu Satho; Keiichi Irie; Mineo Watanabe; Masato Hosokawa; Yukihiro Hiramatsu; Parimal Talukder; Takahiro Okuno; Shodai Tsuruda; Saori Uyeda; Yuki Fukmits; Yukihiko Nakashima; Masumi Imoto; Akihisa Toda; Nobuhiro Kashige; Fumio Miake
The 53th Annual Meeting of the Japanese Society of Tropical Medicine, 06 Sep. 2012

5種類のLactobacillus属乳酸菌由来ゲノムDNAの抗炎症症作用機構に関する研究

Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Shorta Shimura; Yukihiko Nakasshima; Fumio Miake; Nobuhiro Kashige
The 16th Annual Meeting of Intestinal Microbiology, 14 Jun. 2012

Changes in progranulin expression following focal cerebral ischemia associated with microglial activation in mice

Ayumi Furukawa; Keiichi Irie; Yoshiharu Akitake; Masato Hosokawa; Takafumi Nakano; Carl Muroi; Yuya Sakamoto; Yukihiro Hiramatsu; Saori Uyeda; Yuki Fukumitsu; Tomomitsu Satho; Nobuhiro Kashige; Fumio Miake; Kenichi Mishima; Katsunori Iwasaki; Michihiro Fujiwara
The 89th Annual Meeting of the Physiological Society of Japan, 29 Mar. 2012

乳酸菌由来ゲノムDNAの抗炎症作用機構に関する研究

Yukihiro Hiramatsu; Tomomitsu Satho; Keiichi Irie; Shota Shiimura; Takahiro Okuno; Tanjina Sharimin; Yuki Fukumitsu; Saori Uyeda; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
Annual Meeting of Japan Scoiety for Bioscience, Biotechnology, and Agrochemistry 2012, 25 Mar. 2012

Pyriproxyfen induces Ig G immuno response in BALB/c mice.

Tanjina Sharmin; Tomomitsu Satho; Keiichi Irie; Mineo Watanabe; Yukihiro Hiramatsu; Parimal Talukder; Takahiro Okuno; Shodai Tsuruda; Saori Uyeda; Yukie Tamura; Saori Egawa; Kana Omori; Yukihiko Nakashima; Reiko Eyanagi; Akihisa Toda; Nobuhiro Kashige; Fumio Miake
第39回薬物活性シンポジウム, 21 Nov. 2011

2-Arachidonylglycerol protects against infection by secretion of antimicrobial peptides from the intestinal tract

Saori Uyeda; Keiichi Irie; Takahiro Okuno; Shodai Tsuruda; Mari Ioki; Yukie Tamura; Tomomitsu Satho; Kenichi Mishima; Yukihiko Nakashima; Nobuhiro Kashige; Fumio Miake
IUMS 2011 Sapporo, 06 Sep. 2011

ウコン含有生薬クルクミンが腸管内の自然免疫に与える影響

赤司 唯; 頭島 美幸; 入江 圭一; 佐藤 朝光; 中島 幸彦; 三島 健一; 藤原 道弘; 鹿志毛 信広; 見明 史雄
第28回和漢医薬学会学術大会, 27 Aug. 2011

L-DOPA treatment of adult female Aedes albopictus mosquitoes suggests a relationship between blood-feeding activity and dopamine level

Yuki Fukumitsu; Keiichi Irie; Tomomitsu Satho; Yukihiko Nakashima; Kenichi Mishima; Nobuhiro Kashige; Fumio Miake
8th International Congress of Comparative Physiology and Biochemistry, 03 Jun. 2011

蚊成虫雌における吸血行動と脳内Dopamineの経日的変動の相関性

福光 由起; 入江 圭一; 佐藤 朝光; 鹿志毛 信広; 見明 史雄
第63回日本衛生動物学会, 14 Apr. 2011

Cholera Toxin B と乳酸菌を融合した2ステップ腸管内DDSの開発

奥野 隆啓; 平松 征洋; 入江 圭一; 宮田 健; 戸田 晶久; 佐藤 朝光; 繪柳 玲子; 新川 武; 中島 幸彦; 鹿志毛 信広; 見明 史雄
The 131th Annual Meeting of the Pharmaceutical Society of Japan, 28 Mar. 2011

脂肪酸によるヒト大腸上皮細胞からの抗菌ペプチドLL-37の発現誘導

飯岡 利規; 入江 圭一; Talukder Parimal; 佐藤 朝光; 中島 幸彦; 鹿志毛 信広; 見明 史雄
日本薬学会第131年会, 28 Mar. 2011

2-arachidonylglycerolの腸管病原微生物に対する感染防御への有効性

上田紗織; 入江圭一; 佐藤朝光; 三島健一; 鶴田翔大; 五百木真里; 田村幸恵; 奥野隆啓; 中島幸彦; 岩崎克典; 鹿志毛信広; 藤原道弘; 見明史雄
日本薬学会第131年会, 28 Mar. 2011

亜鉛によるCaco-2細胞からの抗菌ペプチドLL-37の発現誘導

佐藤 朝光; Parimal Talukder; Tanjina Sharmin; 入江 圭一; 中島 幸彦; 鹿志毛 信広; 見明 史雄
第14回 日本病態栄養学会 年次学術集会, 15 Jan. 2011

Trace metal zinc stimulates secretion of antimicrobial peptide LL-37 from Caco-2 cell.

Parimal Talukder; 佐藤 朝光; Tanjina Sharmin; 入江 圭一; 中島 幸彦; 鹿志毛 信広; 見明 史雄
The 27th Annual Meeting of the Pharmaceutical Society of Japan, Kyushu Branch, 12 Dec. 2010

ヒト肺上皮細胞を使用した精油による抗菌ペプチド発現誘導の確認

園田 結理; 瀧下 達也; 頭島 美幸; 佐藤 朝光; 入江 圭一; 中島 幸彦; 鹿志毛 信広; 見明 史雄
The 27th Annual Meeting of the Pharmaceutical Society of Japan, Kyushu Branch, 12 Dec. 2010

C6/36細胞におけるMet遺伝子の部分配列の決定

倉重友和; 佐藤朝光; 福光由起; 入江圭一; 中島幸彦; 鹿志毛信広; 見明史雄
第60回日本衛生動物学会南日本支部大会, 06 Nov. 2010

内因性カンナビノイドによる抗菌ペプチドの発現誘導作用

長戸 麻実; 榎木 麻希子; 入江 圭一; 秋武 義治; 三島 健一; 佐藤 朝光; 鹿志毛 信広; 見明 史雄; 岩崎 克典; 藤原 道弘
日本薬学会 第130年会, 30 Mar. 2010

超臨界二酸化炭素中での超音波を用いた再生医療用細胞外マトリックスの生成

三島健司; 松山清; 入江圭一; 三島健一; 藤原道弘
化学工学会第75年会,K316(鹿児島大), 20 Mar. 2010

内因性カンナビノイド処置ヒト肺上皮細胞株A549における自然免疫賦活作用の発見

榎木麻希子; 入江圭一; 佐藤朝光; 園田結理; 三島健一; 鹿志毛信広; 見明史雄; 藤原道弘
第25回日本薬学会九州支部会, 13 Dec. 2009

Challenge of Interdisciplinary and Integrated Education of Engineering, Medicine, Pharmacology, and Economics in Fukuoka University

K. Mishima; T. Kato; S. Aramaki; K. Irie; K. Mishima; M. Fujiwara; K. Tachibana; K.Saku; M. Abiru; K. Nishijima
ITK-FUKUOKA2009, p11, 07 Nov. 2009

CTB分泌乳酸菌を用いた2ステップ腸管内DDSの開発

宮田健; 奧野隆啓; 平松征洋; 入江圭一; 戸田昌久; 佐藤朝光; 檜柳玲子; 新川武; 中島幸彦; 鹿志毛信宏; 見明史雄
第50回日本熱帯医学会, 22 Oct. 2009

Binary Solid-Liquid-Gas Equilibrium of α-Lipoic Acid/CO2 and Hydrogenated Colza Oil/CO2 Systems

M. Honjo; K. Mishima; K. Mastuyama; K. Irie; K. Mishima; M. Fujiwara
5th International Symposium of Molecular Thermodynamics and Molecular Simulation, 03 Oct. 2009

cholera toxin B分泌乳酸菌を用いた ２ステップ腸管内DDSの開発

奥野隆啓; 平松征洋; 入江圭一; 宮田健; 戸田晶久; 佐藤朝光; 繪柳玲子; 新川武; 中島幸彦; 鹿志毛信広; 見明史雄
日本薬学会第129年会, 25 Mar. 2009

リードスルー活性に着目した前頭側頭葉変性症の新規治療薬の探索

Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C)
Fukuoka University
01 Apr. 2024 - 31 Mar. 2027