SEARCH

Search Details
Last Updated :2024/04/12

endo hitomi

School of Medicine
Lecturer/Senior Assistant Professor

Profile1991/09-1992/03 Depertment of Pathology, Kanagawa Cancer Center. 1993/09-1994/03 Department of Immunology, Medical Institute of Bioregulation.  1994/04-1998/03 Graduate School of Medical Sciences, Kyusyu University. 1998/04-2000/08 Department of Immunology, Medical Institute of Bioregulation. 2000/09-2002/08 Morecular Oncology Center, Fukuoka University.

Researcher information

■ Degree
  • 医学博士, 九州大学
  • M.D & Ph.D, Kyushu University
■ Research Keyword
  • Tumor pathology.
  • Tumor Immunology
  • Gene therapy
  • Therapeutic ultrasound
■ Field Of Study
  • Life sciences, Human pathology, Human Pathology
  • Life sciences, Immunology, Immunology
  • Life sciences, Molecular biology, Morecular Biology
  • Life sciences, Radiology, Ultrasound

Career

■ Career
  • 01 Apr. 2006
    福岡大学医学部 解剖学
  • 19 Aug. 2002 - 31 Mar. 2006
    Research & Development, AstraZeneca japan.
  • 30 Sep. 2000 - 19 Aug. 2002
    福岡大学分子腫瘍学センター ポス・ドクター
  • 01 Aug. 1987 - Aug. 1993
    Liaoning Cancer Hospiral
  • 30 Sep. 1991 - 31 Mar. 1992
    神奈川県立がんセンター 病理科 研修医
■ Educational Background
  • Apr. 1994 - Mar. 1998
    Kyushu University, Graduate School, Division of Medical Sciences, Immunology

Research activity information

■ Award
  • 1993
    China Association for Science and Technology, 中国科学技術協会第1回青年学術年会-遼寧省第1回青年学術年会優秀論文二等賞
    BRDU-抗BRDU方法によって肝細胞癌のPCNA陽性細胞の比較.
■ Paper
  • Influence of Nanobubble Size Distribution on Ultrasound-Mediated Plasmid DNA and Messenger RNA Gene Delivery.
    Hiroshi Kida; Loreto B Feril; Yutaka Irie; Hitomi Endo; Keiji Itaka; Katsuro Tachibana
    Frontiers in pharmacology, 2022
  • Nanobubble Mediated Gene Delivery in Conjunction With a Hand-Held Ultrasound Scanner.
    Hiroshi Kida; Koyo Nishimura; Koki Ogawa; Akiko Watanabe; Loreto B Feril; Yutaka Irie; Hitomi Endo; Shigeru Kawakami; Katsuro Tachibana
    Frontiers in pharmacology, 2020
  • アルブミン保持ナノバブルの物理・超音波画像特性の解析
    Akiko Watanabe; Hong Sheng; Hitomi Endo; Loreto; B .Feril; Yutaka Irie; Koich iOgawa; Seyedeh Moosavi-Nejad; KatsuroTachibana
    Heliyon, 17 Jun. 2019, Refereed
  • Enhanced cell killing and apoptosis of oral squamous cell carcinoma cells with ultrasound in combination with cetuximab coated albumin microbubbles
    Kyoichi Narihira; Akiko Watanabe; Hong Sheng; Hitomi Endo; Loreto B. Feril; Yutaka Irie; Koichi Ogawa; Seyedeh Moosavi-Nejad; Seiji Kondo; Toshihiro Kikuta; Katsuro Tachibana
    Journal of Drug Targeting, 16 Mar. 2018, Refereed
  • Acute effects of sono-activated photocatalytic titanium dioxide nanoparticles on oral squamous cell carcinoma
    S. Moosavi Nejad; Hiromasa Takahashi; Hamid Hosseini; Akiko Watanabe; Hitomi Endo; Kyoichi Narihira; Toshihiro Kikuta; Katsuro Tachibana
    ULTRASONICS SONOCHEMISTRY, Sep. 2016, Refereed
  • Enhanced mechanical damage to in vitro cancer cells by high-intensity-focused ultrasound in the presence of microbubbles and titanium dioxide
    Katsuro Tachibana; Hitomi Endo; Loreto B. Feril; Seyedeh Moosavi Nejad; Hiromasa Takahashi; Kyoichi Narihira; Toshihiro Kikuta
    JOURNAL OF MEDICAL ULTRASONICS, Oct. 2015, Refereed
  • Synergistic inhibition of malignant melanoma proliferation by melphalan combined with ultrasound and microbubbles
    Miki Matsuo; Kazuki Yamaguchi; Loreto B. Feril; Hitomi Endo; Koichi Ogawa; Katsuro Tachibana; Juichiro Nakayama
    ULTRASONICS SONOCHEMISTRY, Sep. 2011
  • Ultrasound activation of TiO2 in melanoma tumors.
    Harada Y; Ogawa K; Irie Y; Endo H; Feril LB Jr; Uemura T; Tachibana K
    J Control Release., Jan. 2011
  • Ultrasound-mediated interferon β gene transfection inhibits growth of malignant melanoma.
    Yamaguchi K; Feril LB Jr; Tachibana K; Takahashi A; Matsuo M; Endo H; Harada Y; Nakayama J
    Biochem Biophys Res Commun., Jan. 2011, Refereed
  • Ultrasound activation of TiO2 in melanoma tumors
    Yoshimi Harada; Koichi Ogawa; Yutaka Irie; Hitomi Endo; Loreto B. Feril; Tetsuji Uemura; Katsuro Tachibana
    JOURNAL OF CONTROLLED RELEASE, Jan. 2011
  • Synergistic effect of ultrasound and antibiotics against Chlamydia trachomatis-infected human epithelial cells in vitro
    Yurika Ikeda-Dantsuji; Loreto B. Feril; Katsuro Tachibana; Koichi Ogawa; Hitomi Endo; Yoshimi Harada; Ryo Suzuki; Kazuo Maruyama
    ULTRASONICS SONOCHEMISTRY, Jan. 2011, Refereed
  • Hypotonia-induced cell swelling enhances ultrasound-induced mechanical damage to cancer cells
    Loreto B. Feril; Katsuro Tachibana; Takashi Kondo; Ryohei Ogawa; Qing-Li Zhao; Kazuki Yamaguchi; Koichi Ogawa; Hitomi Endo; Yutaka Irie; Yoshimi Harada
    JOURNAL OF MEDICAL ULTRASONICS, Jan. 2010, Refereed
  • Growth inhibition of neurofibroma by ultrasound-mediated interferon γ transfection
    Kazuki Yamaguchi; Loreto B. Feril; Yoshimi Harada; Hitomi Endo; Yutaka Irie; Juichiro Nakayama; Katsuro Tachibana
    JOURNAL OF MEDICAL ULTRASONICS, Mar. 2009, Refereed
  • Therapeutic potentials of low-intensity ultrasound(part Ⅱ):Biomolecular effects, sonotransfection and sonopermeabilization
    FERIL Loreto; Tachibana Katsuro; Ogawa K; Ikeda-Dantsuji Y; Endo H; Harada Y; Kondo T; Ogawa R
    J.Med Ultrasonics, Jun. 2008, Refereed
  • Bioeffects of Ultrasound for Therapy
    Feril LB Jr; Tachibana K; Yamaguchi K; Ogawa K; Ikeda-Dantsuji Y; Irie Y; Endo H
    Philippine Physics Journal, 2007, Refereed
  • Generation, immunologic characterization and antitumor effects of human monoclonal antibodies for carcinoembryonic antigen
    Imakiire T; Kuroki M; Shibaguchi H; Abe H; Yamauchi Y; Ueno A; Hirose Y; Yamada H; Yamashita Y; Shirakusa T; Ishida I; Kuroki M
    Int J Cancer, 2004, Refereed
  • Gene transfer with echo-enhanced contrast agents: Comparison between Albunex, Optison, and Levovist in mice - Initial results
    TL Li; K Tachibana; M Kuroki; M Kuroki
    RADIOLOGY, Nov. 2003, Refereed
  • Significance of tumor-associated antigens in the diagnosis and therapy of cancer: An overview
    M Kuroki; A Ueno; H Matsumoto; H Abe; T Li; T Imakiire; Y Yamauchi; K Uno; K Shirota; H Shibaguchi; M Kuroki
    ANTICANCER RESEARCH, Nov. 2002, Refereed
  • Targeted sonodynamic therapy of cancer using a photosensitizer conjugated with antibody against carcinoembryonic antigen
    H Abe; M Kuroki; K Tachibana; TL Li; A Awasthi; A Ueno; H Matsumoto; T Imakiire; Y Yamauchi; H Yamada; A Ariyoshi; M Kuroki
    ANTICANCER RESEARCH, May 2002
  • The restoration of the antitumor T cell response from stress-induced suppression using a traditional Chinese herbal medicine Hochu-ekki-to (TJ-41 : Bu-Zhong-Yi-Qi-Tang)
    TL Li; K Tamada; K Abe; H Tada; Y Onoe; K Tatsugami; M Harada; C Kubo; K Nomoto
    IMMUNOPHARMACOLOGY, Jun. 1999
  • Characterization of B16 melanoma-specific cytotoxic T lymphocytes
    M Harada; K Tamada; K Abe; TL Li; Y Onoe; H Tada; K Tatsugami; T Ando; G Kimura; K Komoto
    CANCER IMMUNOLOGY IMMUNOTHERAPY, Dec. 1998, Refereed
  • Involvement of both donor cytotoxic T lymphocytes and host NK1.1(+) T cells in the thymic atrophy of mice suffering from acute graft-versus-host disease
    Y Onoe; M Harada; K Tamada; K Abe; T Li; H Tada; K Nomoto
    IMMUNOLOGY, Oct. 1998, Refereed
  • IL-4-producing NK1.1(+) T cells are resistant to glucocorticoid-induced apoptosis: Implications for the Th1/Th2 balance
    K Tamada; M Harada; K Abe; TL Li; K Nomoto
    JOURNAL OF IMMUNOLOGY, Aug. 1998, Refereed
  • Vaccination with activated B cells pulsed with tumor-lysates can induce tumor-specific CD4(+) T cells in vivo
    O Ito; M Harada; M Takenoyama; K Tamada; TL Li; K Abe; H Fujie; K Nomoto
    IMMUNOBIOLOGY, Jul. 1998, Refereed
  • Antitumor vaccination effect of dendritic cells can be augmented by locally utilizing Th1-type cytokines from OK432-reactive CD4+ T cells
    K Tamada; M Harada; K Abe; TL Li; H Tada; Y Onoe; K Nomoto
    CANCER IMMUNOLOGY IMMUNOTHERAPY, May 1998, Refereed
  • Systemic administration of interleukin-12 can restore the anti-tumor potential of B16 melanoma-draining lymph node cells impaired at a late tumor-bearing state
    M Harada; K Tamada; K Abe; TL Li; Y Onoe; H Tada; M Takenoyama; K Yasumoto; G Kimura; K Nomoto
    INTERNATIONAL JOURNAL OF CANCER, Jan. 1998, Refereed
  • Early-appearing tumor-infiltrating natural killer cells play an important role in the nitric oxide production of tumor-associated macrophages through their interferon production
    K Abe; M Harada; K Tamada; O Ito; TL Li; K Nomoto
    CANCER IMMUNOLOGY IMMUNOTHERAPY, Jan. 1998, Refereed
  • Repeated restraint stress impairs the antitumor T cell response through its suppressive effect on Th1-type CD4 T cells
    TL Li; M Harada; K Tamada; K Abe; K Nomoto
    ANTICANCER RESEARCH, Nov. 1997, Refereed
  • Immunosuppressive activity of cloned natural killer (NK1.1(+)) T cells established from murine tumor-infiltrating lymphocytes
    K Tamada; M Harada; K Abe; TL Li; H Tada; Y Onoe; K Nomoto
    JOURNAL OF IMMUNOLOGY, May 1997, Refereed
  • Local injections of OK432 can augment the TH1-type T-cell response in tumor-draining lymph node cells and increase their immunotherapeutical potential.
    Okamoto T.; Harada M.; Tamada K.; Yoshida H.; Ito O.; Kong Y.Y.; Takenoyama M.; Hirashima C.; Matsuzaki G.; Nomoto K.
    Int. J. Cancer, Mar. 1997, Refereed
  • Oral administration of PSK can improve the impaired antitumor CD4+ T cell response in gut-associated lymphoid tissue (GALT) of specific pathogen-free mice.
    Harada M; Matsunaga K; Oguchi Y; Iijima H; Tamada K; Abe K; Takenoyama M; Ito O; Kimura G; Nomoto K
    International Journal of Cancer,, 1997, Refereed
  • The augmenting effect of OK432-stimulated B cells on the in vitro generation of anti-tumor cytotoxic T lymphocytes from tumor-draining lymph node cells: The possible role of interleukin-12
    Y Shinomiya; M Harada; K Tamada; S Kurosawa; T Okamoto; H Terao; M Takenoyama; O Ito; C Hirashima; TL Li; T Shirakusa; K Nomoto
    IN VIVO, Jan. 1997, Refereed
  • The antitumor effect induced by local injections with interleukin-2 is diminished by combing with a local injection with mitomycin C
    TL Li; M Harada; K Tamada; K Abe; O Ito; M Takenoyama; K Nomoto
    IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, 1996, Refereed
  • Specific antitumor activity of tumor-infiltrating lymphocytes expanded first in a culture with both anti-CD3 monoclonal antibody and activated B cells and then in a culture with interleukin-2.
    Tamada K; Harada M; Okamoto T; Takenoyama M; Ito O; Matsuzaki G; Nomoto K
    Cancer immunology, immunotherapy : CII, Dec. 1995, Refereed
  • Anti-metastatic activity induced by the in vivo activation of purified protein derivative (PPD)-recognizing Th1 type CD4+ T cells.
    Shinomiya Y; Harada M; Kurosawa S; Okamoto T; Terao H; Matsuzaki G; Shirakusa T; Nomoto K
    Immunobiology, Aug. 1995, Refereed
  • The antitumor activity induced by the in vivo administration of activated B cells bound to anti-CD3 monoclonal antibody.
    Harada M; Okamoto T; Kurosawa S; Shinomiya Y; Ito O; Takenoyama M; Terao H; Matsuzaki G; Kimura G; Nomoto K
    Cellular immunology, Mar. 1995, Refereed
  • The antitumor effect of tumor-draining lymph node cells activated by both anti-CD3 monoclonal antibody and activated B cells as costimulatory-signal-providing cells.
    Okamoto T; Harada M; Shinomiya Y; Matsuzaki G; Nomoto K
    Cancer immunology, immunotherapy : CII, Mar. 1995, Refereed
  • The involvement of transforming growth factor b in the impaired antitumor T cell response at the gut-associated lymphoid tissue (GALT).
    Harada M; Matsuzaga K; Oguchi Y; Iijima H; Ito O; Tamada K; Kimura G; Nomoto K
    Cancer Research, 1995, Refereed
  • CONCOMITANT IMMUNITY AGAINST TUMOR-DEVELOPMENT IS ENHANCED BY THE ORAL-ADMINISTRATION OF A KAMPO MEDICINE, HOCHU-EKKI-TO (TJ-41-BU-ZHONG-YI-QI-TANG)
    M HARADA; K SETA; O ITO; K TAMADA; T LI; H TERAO; M TAKENOYAMA; G KIMURA; K NOMOTO
    IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, 1995, Refereed
  • BRDU-抗BRDU方法によって肝細胞癌のPCNA陽性細胞の比較.
    李鉄麗; 現在名; 遠藤日富美; 清水昭男
    中華病理学雑誌, 1993, Refereed
  • Hodgkin’s diseaseの時間的な傾向.
    李鉄麗; 李陰堂; 王艶
    中華病理学雑誌, 1991, Refereed
■ MISC
  • 超音波・マイクロバブル・抗がん剤の併用による癌細胞株U937への殺細胞効果について
    HARADA Yoshimi; TACHIBANA Katsuro; ENDO Hitomi; LORETO B. Feril jr; YAMAGUCHI Kazuki
    Japanese journal of medical ultrasonics = 超音波医学, 15 Apr. 2008
  • BR1とBR14による低浸襲性超音波の遺伝子導入効果の比較
    ENDO Hitomi; TACHIBANA Katsuro; KUROKI Motomu; KUROKI Masahide
    Journal of medical ultrasonics = 超音波医学, 15 Apr. 2007
■ Lectures, oral presentations, etc.
  • セツキシマブ分子標的化マイクロバブルと超音波を併用した癌細胞殺傷効果
    成平恭一; Seyedeh Moosavi-Nejad; 遠藤日冨美; Loreto Feril; 喜久田利弘; 立花克郎
    日本超音波医学会第89回学術集会, 28 May 2016
  • 酸化チタン光触媒、マイクロバブルとHIFUを併用した癌細胞殺傷効果の検討
    第13回に本超音波治療研究会 共催:第2回超音波分子診断治療研究会, 15 Nov. 2014
  • C32細胞株における酸化チタンと超音波の併用による殺細胞効果について 遠藤日富美、原田慶美、フェリル ロリト、立花克郎
    遠藤日富美; 原田慶美; フェリル ロリト; 立花克郎
    第30回日本脳神経超音波学会総会, 08 Jul. 2011, 日本脳神経超音波学会
  • Comparative analysis of gene transfer efficiency to CHO cells by echo contrast agent BR14 under different ultrasound conditions
    Hitomi Endo; Katsuro Tachibana; Loreto B. Feril, Jr; Yoshimi Harada; Koichi Ogawa; Yutaka Irie
    20th International congress on acoustics, 23 Aug. 2010
  • Comparative analysis of gene transfer efficiency to CHO cells by echo contrast agent BR1 under different ultrasound conditions
    Endo Hitomi; Tachibana Katsuro; FERIL Loreto; Yoshimi Harada; Koichi Ogawa; Yutaka Irie
    11th International Symposium on Ultrasound Contrast Imaging & 1st Asia-Pacific Conference on Ultrasound Contrast Imaging, 18 Dec. 2009
  • 超音波とマイクロバブルを併用したメルファランのメラノーマ細胞に対する増殖抑制効果の検討
    松尾美希; 山口和紀; Loreto B; FERIL Jr; 小川皓一; 遠藤日富美; 今福信一; 立花克郎; 中山樹一
    第22回日本色素細胞学会学術大会, 05 Dec. 2009
  • C32細胞株におけるベルテポルファンと超音波の併用による殺細胞効果について
    原田慶美; 遠藤日富美; フェリル ロリト; 立花克郎
    第8回日本超音波治療研究会(JSTU), 28 Nov. 2009
  • ホルムアルデヒドに対する新しい中和剤散布法の試み(第2報)
    Irie Yutaka; Ogawa Koichi; FERIL Loreto; Endo Hitomi; Tachibana Katsuro
    日本解剖学会 第65回九州支部学術集会, 07 Nov. 2009
  • The effect of cell killing by ultrasound
    Tachibana K; Harada Y; Feril L; Endo H; Ogawa K; Irie Y
    9th International Symposium on Therapeutic Ultrasound, 23 Sep. 2009
  • Hypotonia-Induced Cell Swelling Enhances Ultrasound-Induced Mechanical Damage on Cancers Cells
    FERIL Loreto; Tachibana Katsuro; YAMAGUCHI Kazuki; Ogawa Koichi; Endo Hitomi
    12th World Congress of the World Federation for Ultrasound in Medicine and Biology, 30 Aug. 2009
  • U937細胞株における酸化チタンと超音波併用による殺細胞効果について
    Endo Hitomi; Tachibana Katsuro
    日本超音波医学会第82回学術集会, 24 May 2009
  • ホルムアルデヒドに対する新しい中和剤散布の試み
    Irie Yutaka; Ogawa Koichi; FERIL Loreto; Endo Hitomi; Tachibana Katsuro; Hirakawa kazunori
    日本解剖学会 第64回九州支部学術集会, 25 Oct. 2008
  • The Effects of Low Intensity Ultrasound on Tumors: Preliminary Study in Mice
    Tachibana Katsuro; Endo Hitomi
    平成19年度第2回超音波分子診断治療研究会, 22 Sep. 2007
  • Effect of low-intensity ultrasound on human gastric carcinoma in nude mice
    Endo Hitomi; Tachibana Katsuro; Kondo T; Yamaguchi K
    19th International Congress on Acoustics, 02 Sep. 2007
  • Enhanced Gene Transfer by Echo Contrast Agents: Comparison between BR1 and BR14 in Vitro and in Vivo
    th Annual Meeting American Society of; GENE THERAPY
    10th Annual Meeting American Society of GENE THERAPY, 30 May 2007
  • BR1とBR14による低浸襲性超音波の遺伝子導入効果の比較
    Endo Hitomi; Tachibana Katsuro
    日本超音波医学会第80回学術集会, 19 May 2007
  • Enhanced Gene Transfer by Echo Contrast Agents:Comparison between BR1 and BR14
    Endo Hitomi; Tachibana Katsuro
    第8回国際造影超音波シンポジウム, 08 Dec. 2006
  • ソノポレーション用超音波プローブの性能特性に関する検討
    第; 回国際造影超音波シンポジウム
    第1回ソノポレーション研究会, 15 Jul. 2006
  • マイクロバブルによる超音波遺伝子導入増強効果の検討
    遠藤日富美; 立花克郎; 黒木求; 黒木政秀
    第61回日本癌学会総会, 01 Oct. 2002
  • GENE TRANSFER BY SONOPORATION: COMPARISON OF VARIOUS TYPE OF MICROBUBBLES
    Tieli Li; Katsuro Tachibana; Motomu Kuroki; Hironori Abe; Fumiko Arakawa; Masahide Kuroki
    Asian-Pacific Conference of Tumor Biology, 16 Sep. 2001
  • Negative effect of stress on antitumor immunity and its restoration by Hocho-eki-to (TJ41: Bu-Zhong-Yi-Qi-Tong)
    李鉄麗; 遠藤日富美; 原田守; 玉田耕治; 阿部光一郎; 尾上康宏; 多田斉; 久保千春; 野本亀久雄
    第28回日本免疫学会総会, 02 Dec. 1998
  • 反復性拘束性ストレスが抗腫瘍T細胞免疫応答に及ぼす影響
    李鉄麗; 原田守; 玉田耕治; 阿部光一郎; 尾上康宏; 多田斉; 久保千春; 野本亀久雄
    第26回日本免疫学会総会, 26 Nov. 1996
  • 担癌早期浸潤NK細胞の抗腫瘍特異的CD4またはCD8T細胞の in vivo primingに対する影響
    李鉄麗; 原田守; 寺尾浩; 伊藤理; 玉田耕治; 阿部光一郎; 野本亀久雄
    第25回日本免疫学会総会, 28 Nov. 1995
■ Affiliated academic society
  • Japanese Society for Immunology
  • Japanese Cancer Association
  • The Japan Society of Ultrasonics in Medicine
■ Research Themes
  • ミセル製剤ナノバブルと超音波を併用した新しい超音波がん薬物療法の開発
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B)
    Fukuoka University
    2010 - 2012
  • 酸化チタンと超音波を併用した新しい癌治療への挑戦
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research
    Fukuoka University
    2010 - 2011
  • 低エネルギー超音波を利用した新しい非侵襲的癌治療システムの確立
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C)
    Fukuoka University
    2008 - 2010
  • 超音波エネルギーを利用した新しい免疫療法の研究
    日本学術振興会, 科学研究費助成事業, 萌芽研究
    福岡大学
    2007 - 2008
  • Sweep周波数超音波を用いた標的単体腫瘍細胞への画期的なsiRNA導入法の確立
    日本学術振興会, 科学研究費助成事業, 若手研究(スタートアップ)
    福岡大学
    2006 - 2007