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Last Updated :2024/04/12

ban fumitake

School of Medicine
Lecturer/Senior Assistant Professor

Profile2008年4月- 癌栄養血管を標的とした新規癌遺伝子免疫療法の開発、クラミジアに対する感染防御機構とそのエスケープ機構の解明に関する研究に従事。 2003年10月-2008年3月 細胞内寄生虫原虫(トリパノソーマ、マラリア)に対するDNAワクチン開発に関する研究、ユビキチン・プロテアソーム駅路の活性化戦略を基盤においた癌免疫療法の開発などに従事。

Researcher information

■ Degree
  • 博士(医学), 九州大学
  • Ph.D., Kyushu University
■ Research Keyword
  • Trypanosoma
  • Chlamydia
  • tumor DNA vaccine
■ Field Of Study
  • Life sciences, Parasitology, Parasitology (includes Sanitary Zoology)
  • Life sciences, Bacteriology, Bacteriology(includes Mycology)
  • Life sciences, Immunology, Immunology

Career

■ Career
  • 01 Apr. 2008
    Assistant Professor
■ Educational Background
  • Apr. 2004 - Mar. 2008
    Kyushu University, Graduate School, Division of Medicine, 病態医学専攻
  • Sep. 1995 - Jul. 2000
    Peking University, Faculty of Medicine, Basic Medicine

Research activity information

■ Paper
  • Chlamydia trachomatis targets mitochondrial dynamics to promote intracellular survival and proliferation.
    Kurihara Y; Itoh R; Shimizu A; Walenna NF; Chou B; Ishii K; Soejima T; Fujikane A; Hiromatsu K
    Cell Microbiol., 12 Oct. 2018
  • Chlamydia pneumoniae exploits adipocyte lipid chaperone FABP4 to facilitate fat mobilization and intracellular growth in murine adipocytes.
    Walenna NF; Kurihara Y; Chou B; Ishii K; Soejima T; Itoh R; Shimizu A; Ichinohe T; Hiromatsu K
    Biochem Biophys Res Commun., 01 Jan. 2018
  • Chlamydia pneumoniae harness host NLRP3 inflammasome-mediated caspase-1 activation for optimal intracellular growth in murine macrophages
    Itoh R; Murakami I; Chou B; Ishii K; Soejima T; Suzuki T; Hiromatsu K
    Biochem Biophys Res Commun., 26 Sep. 2014
  • Resistance to malaria by enhanced phagocytosis of erythrocytes in LMP7-deficient mice
    Duan X; Imai T; Chou B; Tu L; Himeno K; Suzue K; Hirai M; Taniguchi T; Okada H; Shimokawa C; Hisaeda H
    PLoS One, 19 Mar. 2013
  • Vitamin D-dependent cathelicidin inhibits Mycobacterium marinum infection in human monocytic cells
    Sato E; Imafuku S; Ishii K; Itoh R; Chou B; Soejima T; Nakayama J; Hiromatsu K
    J Dermatol Sci., 09 Feb. 2013
  • Antiangiogenic tumor therapy by DNA vaccine inducing aquaporin-1-specific CTL based on ubiquitin-proteasome system in mice.
    Chou B; Hiromatsu K; Okano S; Ishii K; Duan X; Sakai T; Murata S; Tanaka K; Himeno K
    J Immunol., Aug. 2012, Refereed
  • Topical vitamin D₃ analogues induce thymic stromal lymphopoietin and cathelicidin in psoriatic skin lesions
    E. Sato-Deguchi; S. Imafuku; B. Chou; K. Ishii; K. Hiromatsu; J. Nakayama
    BRITISH JOURNAL OF DERMATOLOGY, Jul. 2012, Refereed
  • Involvement of CD8+ T cells in protective immunity against murine blood-stage infection with Plasmodium yoelii 17XL strain
    Imai T; Shen J; Chou B; Duan X; Tu L; Tetsutani K; Moriya C; Ishida H; Hamano S; Shimokawa C; Hisaeda H; Himeno K
    Eur J Immunol, Apr. 2010, Refereed
  • Genetic immunization based on the ubiquitin-fusion degradation pathway against Trypanosoma cruzi
    Chou B; Hiromatsu K; Hisaeda H; Duan X; Imai T; Murata S; Tanaka K; Himeno K
    Biochem Biophys Res Commun., Feb. 2010, Refereed
  • Efficient protective immunity against Trypanosoma cruzi infection after nasal vaccination with recombinant Sendai virus vector expressing amastigote surface protein-2
    Duan X; Yonemitsu Y; Chou B; Yoshida K; Tanaka S; Hasegawa M; Tetsutani K; Ishida H; Himeno K; Hisaeda H
    Vaccine, Oct. 2009, Refereed
  • Critical contribution of immunoproteasomes in the induction of protective immunity against Trypanosoma cruzi in mice vaccinated with a plasmid encoding a CTL epitope fused to green fluorescence protein
    Bin Chou; Hajime Hisaeda; Jianying Shen; Xuefeng Duan; Takashi Imai; Liping Tu; Shigeo Murata; Keiji Tanaka; Kunisuke Himeno
    MICROBES AND INFECTION, Mar. 2008, Refereed
  • Malaria parasites require TLR9 signaling for immune evasion by activating regulatory T cells
    Hajime Hisaeda; Kohhei Tetsutani; Takashi Imai; Chikako Moriya; Liping Tu; Shinjiro Hamano; Xuefeng Duan; Bin Chou; Hidekazu Ishida; Akiko Aramaki; Jianying Shen; Ken J. Ishii; Cevayir Coban; Shizuo Akira; Kiyoshi Takeda; Koji Yasutomo; Motomi Torii; Kunisuke Himeno
    JOURNAL OF IMMUNOLOGY, Feb. 2008, Refereed
  • Ubiquitin-fusion degradation pathway: a new strategy for inducing CD8 cells specific for mycobacterial HSP65
    Shen, J; H. Hisaeda; B. Chou; Q. Yu; L. Tu; K. Himeno
    Biochemical and biophysical research communications, Jan. 2008, Refereed
  • The ubiquitin-proteasome system plays essential roles in presenting an 8-mer CTL epitope expressed in APC to corresponding CD8+ T cells
    Duan, X; H. Hisaeda; J. Shen; L. Tu; T. Imai; B. Chou; S. Murata; T. Chiba; K. Tanaka; H. J. Fehling; T. Koga; K. Sueishi; K. Himeno
    International immunology, May 2006, Refereed
  • A novel DNA vaccine based on ubiquitin-proteasome pathway targeting 'self'-antigens expressed in melanoma/melanocyte
    Zhang, M; C. Obata; H. Hisaeda; K. Ishii; S. Murata; T. Chiba; K. Tanaka; Y. Li; M. Furue; B. Chou; T. Imai; X. Duan; K. Himeno
    Gene therapy, Jul. 2005, Refereed
■ Affiliated academic society
  • 日本免疫学会
  • 日本細菌学会