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Last Updated :2024/04/12

yamakawa hirofumi

Radioisotope Center
Assistant Lecturer/Assistant professor

Researcher information

■ Degree
  • 学士, 福岡大学薬学部

Research activity information

■ Paper
  • Cationic N,N-Dimethylglycine Ester Prodrug of 2R-α-Tocotrienol Promotes Intestinal Absorption via Efficient Self-Micellization with Intrinsic Bile Acid Anion
    Molecules, 23 Apr. 2022, Refereed
  • Cationic N,N-Dimethylglycine Ester Prodrug of 2R-α-Tocotrienol Promotes Intestinal Absorption via Efficient Self-Micellization with Intrinsic Bile Acid Anion.
    Watase D; Setoguchi S; Nagata-Akaho N; Goto S; Yamakawa H; Yamada A; Koga M; Karube Y; Matsunaga K; Takata J
    Molecules, Apr. 2022, Refereed
  • Growth Inhibitory Effects of Ester Derivatives of Menahydroquinone-4, the Reduced Form of Vitamin K2(20), on All-Trans Retinoic Acid-Resistant HL60 Cell Line
    Pharmaceutics, 2021, Refereed
  • Atypical Antipsychotic Drug Ziprasidone Protects against Rotenone-Induced Neurotoxicity: An In Vitro Study
    Terada K; Murata A; Toki E; Goto S; Yamakawa H; Setoguchi S; Watase D; Koga M; Takata J; Matsunaga K; Karube Y
    Molecules, 2020, Refereed
  • Evaluation of photostability and phototoxicity of esterified derivatives of ubiquinol‐10 and their application as prodrugs of reduced coenzyme Q10 for topical administration
    2020, Refereed
  • Ester derivatives of phyllohydroquinone effectively deliver the active form of vitamin K1 topically, owing to their non-photosensitivity
    2020, Refereed
  • Prodrugs for Skin Delivery of Menahydroquinone-4, an Active Form of Vitamin K2(20), Could Overcome the Photoinstability and Phototoxicity of Vitamin K2(20)
    2019, Refereed
  • Antitumor Effects and Delivery Profiles of Menahydroquinone-4 Prodrugs with Ionic or Nonionic Promoiety to Hepatocellular Carcinoma Cells
    2018, Refereed
■ Lectures, oral presentations, etc.
  • Ubiquinol-10エステル誘導体によるUbiquinol-10及びUbiquinone-10の光安定性と光毒性の克服及び表皮角化細胞への送達性
    ビタミン学会, 2020
  • オールトランスレチノイン酸耐性 HL60 細胞に対するメナヒドロキノン-4 エステル誘導体の増殖抑制効果
    日本癌学会, 2020
  • 原発事故により発生する放射性ストロンチウムに関する調査研究
    平成29年度放射線安全取扱部会年次大会, 12 Oct. 2017