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Last Updated :2024/04/12
hiraishi keizo
School of Medicine
Assistant Lecturer/Assistant professor
Research activity information
■ Award
■ Research Themes
- Nov. 2019
第29回日本循環薬理学会・第55回高血圧関連疾患モデル学会 合同学会, 優秀演題賞
肺動脈高血圧症の病態形成におけるTRPM7の役割の検討
平石敬三;倉原琳;崔媛媛;井上隆司 - Nov. 2019
第71回日本生理学会中国四国地方会, 奨励賞
大建中湯はTRPA1チャネルの活性化により腸管線維化を改善する
平石敬三;倉原琳;鬼塚美樹;古賀佳織;竹田津英稔;平野勝也;井上隆司 - Aug. 2019
第61回日本平滑筋学会総会, 学術交流優秀賞
肺動脈リモデリングにおけるSTAT3関連シグナルの探索
平石敬三;倉原琳;崔媛媛;井上隆司 - Aug. 2017
第59回日本平滑筋学会総会, 優秀演題賞
肺動脈高血圧症の病態生理における血管内皮TRPM7チャネルの役割
平石敬三;倉原琳;胡耀鵬;古賀佳織;鬼塚美樹;阿部弘太郎;佐藤徹;岡田泰昌;井上隆司 - May 2016
2016 International Conference of Physiological Sciences, Young Investigator Travel Award
Contribution of TRPM7 and FYN to Endothelial remodeling in HUVECs and HPAECs.
Keizo Hiraishi;Lin-Hai Kurahara;Ryuji Inoue
- The Role of TRPM4 in Cardiac Electrophysiology and Arrhythmogenesis
Yaopeng Hu; Jiehui Cang; Keizo Hiraishi; Takayuki Fujita; Ryuji Inoue
International Journal of Molecular Sciences, 22 Jul. 2023 - Lactulose Modulates the Structure of Gut Microbiota and Alleviates Colitis-Associated Tumorigenesis.
Keizo Hiraishi; Feiyan Zhao; Lin-Hai Kurahara; Xiaodong Li; Tetsuo Yamashita; Takeshi Hashimoto; Yoko Matsuda; Zhihong Sun; Heping Zhang; Katsuya Hirano
Nutrients, 03 Feb. 2022 - Potential of the TRPM7 channel as a novel therapeutic target for pulmonary arterial hypertension.
Keizo Hiraishi; Lin Hai Kurahara; Kaori Ishikawa; Tetsuhiko Go; Naoya Yokota; Yaopeng Hu; Takayuki Fujita; Ryuji Inoue; Katsuya Hirano
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2022 - An Arrhythmic Mutation E7K Facilitates TRPM4 Channel Activation via Enhanced PIP2 Interaction.
Yaopeng Hu; Qin Li; Lin-Hai Kurahara; Narumi Shioi; Keizo Hiraishi; Takayuki Fujita; Xin Zhu; Ryuji Inoue
Cells, 22 Apr. 2021 - Inhibitory Effects of Breast Milk-Derived Lactobacillus rhamnosus Probio-M9 on Colitis-Associated Carcinogenesis by Restoration of the Gut Microbiota in a Mouse Model.
Haiyan Xu; Keizo Hiraishi; Lin-Hai Kurahara; Yuko Nakano-Narusawa; Xiaodong Li; Yaopeng Hu; Yoko Matsuda; Heping Zhang; Katsuya Hirano
Nutrients, 30 Mar. 2021 - Substantial involvement of TRPM7 inhibition in the therapeutic effect of Ophiocordyceps sinensis on pulmonary hypertension.
Keizo Hiraishi; Lin Hai Kurahara; Jianlin Feng; Aya Yamamura; Yuanyuan Cui; Eiji Yahiro; Hiroyasu Yokomise; Tetsuhiko Go; Kaori Ishikawa; Naoya Yokota; Atsushi Fujiwara; Miki Onitsuka; Kohtaro Abe; Shoji Ohga; Toru Satoh; Yasumasa Okada; Lixia Yue; Ryuji Inoue; Katsuya Hirano
Translational research : the journal of laboratory and clinical medicine, 07 Mar. 2021 - Eicosapentaenoic acid ameliorates pulmonary hypertension via inhibition of tyrosine kinase Fyn
Lin Hai Kurahara; Keizo Hiraishi; Aya Yamamura; Ying Zhang; Kohtaro Abe; Eiji Yahiro; Mikiko Aoki; Kaori Koga; Hiroyasu Yokomise; Tetsuhiko Go; Kaori Ishikawa; Zhang Bo; Hiroko Kishi; Sei Kobayashi; Narumi Aoki-Shoi; Satoh Toru; Ryuji Inoue; Katsuya Hirano
Journal of Molecular and Cellular Cardiology, Nov. 2020, Refereed - TRP channels in cardiac and intestinal fibrosis
Ryuji Inoue; Lin-Hai Kurahara; Keizo Hiraishi
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, Oct. 2019 - Implications of immune-inflammatory responses in smooth muscle dysfunction and disease.
Fumitake Usui-Kawanishi; Masafumi Takahashi; Hiroyasu Sakai; Wataru Suto; Yuki Kai; Yoshihiko Chiba; Keizo Hiraishi; Lin Hai Kurahara; Masatoshi Hori; Ryuji Inoue
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2019 - Daikenchuto (Da-Jian-Zhong-Tang) ameliorates intestinal fibrosis by activating myofibroblast transient receptor potential ankyrin 1 channel
Keizo Hiraishi; Lin-Hai Kurahara; Miho Sumiyoshi; Yao-Peng Hu; Kaori Koga; Miki Onitsuka; Daibo Kojima; Lixia Yue; Hidetoshi Takedatsu; Yu-Wen Jian; Ryuji Inoue
WORLD JOURNAL OF GASTROENTEROLOGY, Sep. 2018
Lead - Activation of Myofibroblast TRPA1 by Steroids and Pirfenidone Ameliorates Fibrosis in Experimental Crohn's Disease
Lin Hai Kurahara; Keizo Hiraishi; Yaopeng Hu; Kaori Koga; Miki Onitsuka; Mayumi Doi; Kunihiko Aoyagi; Hidetoshi Takedatsu; Daibo Kojima; Yoshitaka Fujihara; Yuwen Jian; Ryuji Inoue
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2018 - Uncovering the arrhythmogenic potential of TRPM4 activation in atrial-derived HL-1 cells using novel recording and numerical approaches
Yaopeng Hu; Yubin Duan; Ayako Takeuchi; Lin Hai-Kurahara; Jun Ichikawa; Keizo Hiraishi; Tomohiro Numata; Hiroki Ohara; Gentaro Iribe; Michio Nakaya; Masayuki X. Mori; Satoshi Matsuoka; Genshan Ma; Ryuji Inoue
CARDIOVASCULAR RESEARCH, Aug. 2017 - Significant contribution of TRPC6 channel-mediated Ca2+ influx to the pathogenesis of Crohn’s disease fibrotic stenosis
Lin Hai Kurahara; Keizo Hiraishi; Miho Sumiyoshi; Mayumi Doi; Yaopeng Hu; Kunihiko Aoyagi; Yuwen Jian; Ryuji Inoue
Journal of Smooth Muscle Research, 2016 - Modulation of Cardiac Connexin-43 by Omega-3 Fatty Acid Ethyl-Ester Supplementation Demonstrated in Spontaneously Diabetic Rats
J. RADOSINSKA; L. H. KURAHARA; K. HIRAISHI; C. VICZENCZOVA; T. EGAN BENOVA; B. SZEIFFOVA BACOVA; V. DOSENKO; J. NAVAROVA; B. OBSITNIK; I. IMANAGA; T. SOUKUP; N. TRIBULOVA
Physiological Research, 29 Dec. 2015 - Intestinal Myofibroblast TRPC6 Channel May Contribute to Stenotic Fibrosis in Crohn's Disease
Lin Hai Kurahara; Miho Sumiyoshi; Kunihiko Aoyagi; Keizo Hiraishi; Kyoko Nakajima; Midori Nakagawa; Yaopeng Hu; Ryuji Inoue
INFLAMMATORY BOWEL DISEASES, Mar. 2015 - Estimation of the orientation of heme in cytochrome c immobilized on a carboxylate-terminated alkanethiol monolayer on a Au electrode by the use of electroreflectance spectroscopy with polarized light incidence
Takamasa Sagara; Yuu Kubo; Keizo Hiraishi
JOURNAL OF PHYSICAL CHEMISTRY B, Aug. 2006
- 徐脈性不整脈遺伝子変異TRPM4-E7Kチャネルの数理モデルシミュレーション
胡 耀鵬; 平石 敬三; 倉原 琳; 沼田 朋大; 井上 隆司
日本生理学雑誌, Feb. 2019 - 共培養系を用いた線維芽細胞による心房興奮伝播制御機構の検討
胡 耀鵬; 平石 敬三; 倉原 琳; 市川 純; 沼田 朋大; 井上 隆司
日本生理学雑誌, Feb. 2017
- “Chapter8 : Intestinal Fibroblast/myofibroblast TRP Channels.”, New Insights into Inflammatory Bowel Disease
LH. Kurahara; K. Hiraishi; K. Aoyagi; Y. Hu; M. Sumiyoshi; R. Inoue, Joint work
2016
- 冬虫夏草Ophiocordyceps sinensisの肺高血圧症改善効果
平石敬三; 倉原琳; 石川かおり; 平野勝也
第72回日本生理学会中国四国地方会, Nov. 2020 - 母乳由来プロバイオティクスによるAOM/DSS誘導大腸癌モデルマウスへの改善効果
平石敬三; 徐海燕; 倉原琳; 張和平; 平野勝也; 井上隆司
第97回日本生理学会大会, Mar. 2020 - Pathophysiological contribution of TRPM7 channel to pulmonary arterial hypertension
Keizo Hiraishi; Lin-Hai Kurahara; Yuanyuan Cui; Ryuji Inoue
64th Annual Meeting of the Biophysical Society, Feb. 2020 - 大建中湯はTRPA1チャネルの活性化により腸管線維化を改善する
平石敬三; 倉原琳; 鬼塚美樹; 古賀佳織; 竹田津英稔; 平野勝也; 井上隆司
第71回日本生理学会中国四国地方会, Nov. 2019 - 肺動脈高血圧症の病態形成におけるTRPM7の役割の検討
平石敬三; 倉原琳; 崔媛媛; 井上隆司
第29回日本循環薬理学会・第55回高血圧関連疾患モデル学会 合同学会, Nov. 2019 - 肺動脈リモデリングにおけるSTAT3関連シグナルの探索
平石敬三; 倉原琳; 崔媛媛; 井上隆司
第61回日本平滑筋学会総会, Aug. 2019 - 冬虫夏草Ophiocordyceps sinensisによるTRPM7チャネル抑制を介した肺動脈高血圧症改善効果
平石敬三; 倉原琳; Yue Lixia; 山村彩; Feng Jianlin; 阿部弘太郎; 佐藤徹; 岡田泰昌; 井上隆司
第92回日本薬理学会年会, Mar. 2019 - 肺動脈高血圧症の病態形成におけるTRPM7チャネルの役割
平石敬三; 倉原琳; Yue Lixia; Feng Jianlin; 胡耀鵬; 井上隆司
第60回日本平滑筋学会総会, Aug. 2018 - Daikenchuto (Da-Jian-Zhong-Tang) ameliorates intestinal myofibroblasts by activating TRPA1 channel
Keizo Hiraishi; Lin-Hai Kurahara; Yaopeng Hu; Kaori Koga; Miki Onitsuka; Ryuji Inoue
9th FAOPS (Federation of the Asian and Oceanian Physiological Societies) Congress,, Mar. 2018 - Contribution of TRPM7 and FYN to Endothelial remodeling in HUVECs and HPAECs.
Keizo Hiraishi; Lin-Hai Kurahara; Ryuji Inoue
2016 International Conference of Physiological Sciences, Sep. 2016 - Contribution of Endothelial TRPM7 and FYN to Arterial Vascular remodeling
Keizo Hiraishi; Lin-Hai Kurahara; Yaopeng Hu; Ryuji Inoue
第13回日韓シンポジウム, Aug. 2016
■ Research Themes
