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Last Updated :2024/04/14

matsusue aya

School of Medicine
Lecturer/Senior Assistant Professor

Researcher information

■ Degree
  • 医学博士
■ Research Keyword
  • genetic background
  • sudden cardiac death
  • rhabdomyolysis
  • drug
  • autopsy case
■ Field Of Study
  • Life sciences, Forensic medicine, Forensic Medicine

Career

■ Educational Background
  • Kyushu University, Faculty of Pharmaceutical Science, 薬学科
  • Kyushu University, Graduate School, Division of Pharmaceutical Sciences, 薬学

Research activity information

■ Paper
  • Urinary phenylacetylglutamine as a possible biomarker for central nervous system disorders in forensic autopsy cases
    Natsuki Ikematsu; Kenji Hara; Brian Waters; Aya Matsusue; Mio Takayama; Masayuki Kashiwagi; Shin-ichi Kubo
    Legal Medicine, Sep. 2023, Refereed
  • Giant intracranial arteriovenous malformation as a possibility of epileptic seizures in a case of drowning
    Takayama M; Kashiwagi M; Hara K; Matsusue A; Waters B; Kubo SI
    Legal Medicine, Nov. 2022, Refereed
  • Associations between variable number tandem repeat polymorphism in the monoamine oxidase A with cerebrospinal fluid levels in drug positive cases
    Matsusue A; Ishikawa T; Ikeda T; Tani N; Maeda T; Kashiwagi M; Hara K; Waters B; Takayama M; Kubo SI
    2022, Refereed
    Lead
  • A validated method for the separation of ethyl glucoside isomers by gas chromatography-tandem mass spectrometry and quantitation in human whole blood and urine
    Waters B; Nakano R; Hara K; Matsusue A; Kashiwagi M; Kubo SI
    J Chromatogr B Analyt Technol Biomed Life Sci., 2022, Refereed
  • Diagnostic meaning of urinary ethyl glucoside concentrations in relationship to alcoholic beverage consumption
    Nakano R; Waters B; Hara K; Takayama M; Matsusue A; Kashiwagi M; Kubo SI
    Leg Med, 2022, Refereed
  • Immunohistochem ical Investigation of Drug Related Renal Cell Changes
    Ishigami A; Waters B; Kashiwagi M; Matsusue A; Takayama M; Ikematsu N; Kondo T; Kubo S
    Albanian Journal of Medical and Health Sciences, 2022, Refereed
  • 法医剖検例における脳動静脈奇形の診断意義について
    髙山みお; 柏木正之; 原 健二; 松末 綾; Brian Waters; 久保真一
    法医病理, 2022, Refereed
  • エネルギー分散型蛍光X線分析による白骨化死体の青緑色着色物質の解析
    柏木正之; 辻��田 明; 髙山みお; 松末 綾; Brian Waters; 中野涼子; 久保真一
    法医学の実際と研究, 2022
  • 覚醒剤による腎障害:法医学の立場から
    久保真一; 石上安希子; 松末 綾
    別冊 日本臨床 領域別症候群シリーズ No.25 腎臓症候群(第3版)(IV)−その他の腎臓疾患を含めて−, 2022
  • A comparative study of pleural effusion in water area, water temperature and postmortem interval in forensic autopsy cases of drowning
    Ishigami A; Kashiwagi M; Ishida Y; Hara K; Nosaka M; Matsusue A; Yamamoto H; Waters B; Kondo T; Kubo S
    Scientific Reports, 02 Nov. 2021
  • Effects of putrefaction on the quantitative analyses of diphenhydramine in blood and tissues: model experiments by the routine matrix-matched calibration method and standard addition method with different internal standards
    Kudo K; Saka K; Waters B; Hara K; Matsusue A; Kashiwagi M; Kubo S
    FORENSIC TOXICOLOGY, Jul. 2021, Refereed
  • 液体クロマトグラフィータンデム質量分析計を用いた毛髪からの睡眠導入剤の分析法の実務応用.
    Brian Waters; 原 健二; 柏木正之; 松末 綾; 髙山みお; 久保真一
    法医学の実際と研究, 2021
  • A large interhemispheric glioependymal cyst associated with partial defect of the corpus callosum in an elderly man
    Takayama M, Kashiwagi M, Hara K, Matsusue A, Waters B, Kubo SI
    Neuropathology, 14 Jul. 2020, Refereed
  • 局所麻酔薬メピバカイン中毒による低酸素脳症の1例:麻酔時の血中濃度の推定を中心として
    大脇涼子; Brian Waters; 原 健二; 松末 綾; 柏木正之; 久保真一
    法医学の実際と研究, 2020
  • An autopsy case of acute ethanol intoxication with a high concentration of caffeine: A warning about dangerous.
    Waters B; Takayama M; Kashiwagi M; Hara K; Matsusue A; Kubo SI
    日本アルコール・薬物医学会雑誌, 2020
  • Organ distribution of endogenous p-cresol in hemodialysis patients.
    Ikematsu N; Kashiwagi M; Hara K; Waters B; Matsusue A; Takayama M; Kubo SI
    J Med Invest., 2019
  • VNTR polymorphism in the monoamine oxidase A promoter region and cerebrospinal fluid catecholamine concentrations in forensic autopsy cases.
    Matsusue A; Kubo SI; Ikeda T; Tani N; Maeda T; Kashiwagi M; Hara K; Waters B; Takayama M; Ikematsu N; Ishikawa T
    Neurosci Lett., 2019, Refereed
    Lead
  • Japaneseplex: A forensic SNP assay for identification of Japanese people using Japanese-specific alleles.
    Yuasa I; Akane A; Yamamoto T; Matsusue A; Endoh M; Nakagawa M; Umetsu K; Ishikawa T; Iino M
    Legal medicine (Tokyo, Japan), Apr. 2018, Refereed
  • An unusual case of suicide by methanol ingestion.
    Waters B; Hara K; Ikematsu N; Takayama M; Matsusue A; Kashiwagi M; Kubo SI
    Forensic Sci Int., 2018, Refereed
  • Tissue Distribution of Suvorexant in Three Forensic Autopsy Cases.
    Waters B; Hara K; Ikematsu N; Takayama M; Matsusue A; Kashiwagi M; Kubo SI
    J Anal Toxicol., 2018, Refereed
  • Diagnostic meaning of blood p-cresol concentration in forensic autopsy cases.
    Ikematsu N; Kashiwagi M; Hara K; Waters B; Matsusue A; Takayama M; Kubo SI
    Leg Med, 2018, Refereed
  • No association between cardiac ion channel variants and sudden infant death.
    Yamamoto T; Matsusue A; Umehara T; Kubo SI; Ikematsu K
    Pediatr Int., 2018, Refereed
  • Effects of PCR inhibitors on mRNA expression for human blood identification.
    Matsumura S; Matsusue A; Waters B; Kashiwagi M; Hara K; Kubo SI
    Leg Med, 2018, Refereed
  • A modified direct-heating headspace solid-phase microextraction method for drug screening with urine samples.
    Fujii H; Waters B; Hara K; Ikematsu N; Takayama M; Matsusue A; Kashiwagi M; Kubo S
    Forensic Toxicol., 2018, Refereed
  • Subarachnoid hemorrhage in a Japanese cocaine abuser: Cocaine-related sudden death.
    Takayama M; Waters B; Fujii H; Hara K; Kashiwagi M; Matsusue A; Ikematsu N; Kubo S
    Leg Med., 2018, Refereed
  • Quantitation of tetrodotoxin in postmortem specimens using SPE and HILIC LC-MS/MS: Tissue distribution of a forensic autopsy case.
    Waters B; Hara K; Ikematsu N; Takayama M; Matsusue A; Kashiwagi M; Kubo S
    Jpn J Forensic Sci Tech., 2018, Refereed
  • Giant intracranial arteriovenous malformation as the focus of epileptic seizures.
    Takayama M; Hara K; Matsusue A; Waters B; Ikematsu N; Kashiwagi M; Kubo SI
    Neuropathology, 2018, Refereed
  • DRD2/ANKK1 gene polymorphisms in forensic autopsies of methamphetamine intoxication fatalities.
    Matsusue A; Ishikawa T; Ikeda T; Tani N; Arima H; Waters B; Hara K; Kashiwagi M; Takayama M; Ikematsu N; Kubo SI
    Leg Med, 2018, Refereed
    Lead
  • Association between cytochrome P450 2D6 polymorphisms and body fluid methamphetamine concentrations in Japanese forensic autopsy cases.
    Matsusue A; Ikeda T; Tani N; Waters B; Hara K; Kashiwagi M; Takayama M; Ikematsu N; Kubo SI; Ishikawa T
    Forensic Sci Int., 2018, Refereed
    Lead
  • Postmortem genetic analysis of sudden unexpected death in infancy: neonatal genetic screening may enable the prevention of sudden infant death
    Yuki Oshima; Takuma Yamamoto; Taisuke Ishikawa; Hiroyuki Mishima; Aya Matsusue; Takahiro Umehara; Takehiko Murase; Yuki Abe; Shin-ichi Kubo; Koh-ichiro Yoshiura; Naomasa Makita; Kazuya Ikematsu
    JOURNAL OF HUMAN GENETICS, Nov. 2017
  • Basal subarachnoid hemorrhage by rupture of arteriovenous malformation at the cerebellopontine angle
    Mio Takayama; Masayuki Kashiwagi; Kenji Hara; Aya Matsusue; Brian Waters; Natsuki Ikematsu; Shin-ichi Kubo
    NEUROPATHOLOGY, Oct. 2017
  • An autopsy case of serotonin syndrome induced by illegal antipsychotics
    Mio Takayama; Brian Waters; Kenji Hara; Masayuki Kashiwagi; Aya Matsusue; Hiroshi Fujii; Natsuki Ikematsu; Shin-ichi Kubo
    ROMANIAN JOURNAL OF LEGAL MEDICINE, Sep. 2017
  • Volatile Hydrocarbon Analysis in Blood by Headspace Solid-Phase Microextraction: The Interpretation of VHC Patterns in Fire-Related Incidents
    Brian Waters; Kenji Hara; Natsuki Ikematsu; Mio Takayama; Masayuki Kashiwagi; Aya Matsusue; Shin-ichi Kubo
    JOURNAL OF ANALYTICAL TOXICOLOGY, May 2017
  • 法医剖検例における血中カフェイン濃度の概要.
    MATSUSUE Aya; KUBO Shin-Ichi; KASHIWAGI Masayuki; HARA Kenji; WATERS Brian; TAKAYAMA Mio
    日本アルコール・薬物医学会雑誌, 2017
  • 正座が原因と考えられた肺血栓塞栓症の1剖検例.
    MATSUSUE Aya; KUBO Shin-Ichi; KASHIWAGI Masayuki; HARA Kenji; WATERS Brian; TAKAYAMA Mio
    法医学の実際と研究, 2017
  • Simple regioisomeric differentiation of 2-, 3- and 4-methyl-α-pyrrolidinobutiophenones by gas chromatography–mass spectrometry using bromination.
    Hiroshi Fujii; Brian Waters; Kenji Hara; Masayuki Kashiwagi; Aya Matsusue; Shin-ichi Kubo
    FORENSIC TOXICOLOGY, Jan. 2017
  • Association between cerebrospinal fluid dopamine concentrations and catechol-O-methyltransferase gene polymorphisms in forensic autopsy cases of methamphetamine abusers
    Aya Matsusue; Takaki Ishikawa; Tomomi Michiue; Brian Waters; Kenji Hara; Masayuki Kashiwagi; Mio Takayama; Natsuki Ikematsu; Shin-ichi Kubo
    FORENSIC SCIENCE INTERNATIONAL, Jan. 2017, Refereed
    Lead
  • An unexpected death due to massive ascites and a giant mucinous ovarian cystadenoma
    Masayuki Kashiwagi; Mio Takayama; Tomoko Sugimura; Aya Matsusue; Kenji Hara; Brian Waters; Shin-ichi Kubo
    LEGAL MEDICINE, Nov. 2016
  • Quantification of immunohistochemical findings of neurofibrillary tangles and senile plaques for a diagnosis of dementia in forensic autopsy cases
    Mio Takayama; Masayuki Kashiwagi; Aya Matsusue; Brian Waters; Kenji Hara; Natsuki Ikematsu; Shin-ichi Kubo
    LEGAL MEDICINE, Sep. 2016
  • Application of mRNA Expression Analysis to Human Blood Identification in Degenerated Samples that were False-negative by Immunochromatography
    Shusaku Matsumura; Aya Matsusue; Brian Waters; Masayuki Kashiwagi; Kenji Hara; Shin-ichi Kubo
    JOURNAL OF FORENSIC SCIENCES, Jul. 2016
  • Genotyping of the c.1423C>T (p.P475S) polymorphism in the ADAMTS13 gene by APLP and HRM assays: Northeastern Asian origin of the mutant
    Mayumi Nakagawa; Aya Matsusue; Kazuo Umetsu; Morio Iino; Takaki Ishikawa; Isao Yuasa
    LEGAL MEDICINE, Jul. 2016
  • Development of a preparation method to produce a single sample that can be applied to both LC-MS/MS and GC-MS for the screening of postmortem specimens
    Kenji Hara; Brian Waters; Natsuki Ikematsu; Tomoko Tokuyasu; Hiroshi Fujii; Mio Takayama; Aya Matsusue; Masayuki Kashiwagi; Shin-ichi Kubo
    LEGAL MEDICINE, Jul. 2016
  • GC-PCI-MS/MS and LC-ESI-MS/MS databases for the detection of 104 psychotropic compounds (synthetic cannabinoids, synthetic cathinones, phenethylamine derivatives)
    Brian Waters; Natsuki Ikematsu; Kenji Hara; Hiroshi Fujii; Tomoko Tokuyasu; Mio Takayama; Aya Matsusue; Masayuki Kashiwagi; Shin-ichi Kubo
    LEGAL MEDICINE, May 2016
  • The global distribution of the p.R1193Q polymorphism in the SCN5A gene
    Aya Matsusue; Isao Yuasa; Kazuo Umetsu; Nori Nakayashiki; Koji Dewa; Hiroaki Nishimukai; Masayuki Kashiwagi; Kenji Hara; Brian Waters; Mio Takayama; Natsuki Ikematsu; Shin-ichi Kubo
    LEGAL MEDICINE, Mar. 2016, Refereed
    Lead
  • Quantification of neuropathological findings by image data for the diagnosis of dementia in forensic autopsy cases.
    Takayama M; Kashiwagi M; Matsusue A; Waters B; Hara K; Ikematsu N; Kubo S
    J Med Invest., 2016
  • 薬毒物検査によるケトン体分析システムの提案 –法医剖検例における病態補助診断として–
    池松夏紀; 柏木正之; 原 健二; 松末 綾; Brian Waters; 髙山みお; 久保真一
    法医学の実際と研究, 2016
  • カフェイン飲料・製剤の過剰摂取によるカフェイン中毒事故の1剖検例.
    髙山みお; Brian Waters; 原 健二; 柏木正之; 松末 綾; 池松夏紀; 久保真一
    日本アルコール・薬物医学会雑誌, 2016
  • Investigation of Japanese-specific alleles: Most are of Jomon lineage
    Isao Yuasa; Kazuo Umetsu; Noboru Adachi; Aya Matsusue; Nori Nakayashiki; Junko Fujihara; Atsushi Akane; Shinji Harihara; Feng Jin; Takaki Ishikawa
    LEGAL MEDICINE, Jan. 2015
  • Direct-heating headspace solid-phase microextraction for the screening of illicit drugs
    Hiroshi Fujii; Brian Waters; Kenji Hara; Masayuki Kashiwagi; Aya Matsusue; Mio Takayama; Shin-ichi Kubo
    FORENSIC TOXICOLOGY, Jan. 2015
  • 強皮症の1剖検例:心肥大の発生機序の検討.
    髙山みお; 柏木正之; 原 健二; 松末 綾; Brian Waters; 池松夏紀; 久保真一
    法医学の実際と研究, 2015
  • 食道・胃破裂を認めた解熱鎮痛剤中毒死の1剖検例.
    髙山みお; Brian Waters; 原 健二; 松末 綾; 柏木正之; 久保真一
    法医学の実際と研究, 2014
  • A hypervariable STR polymorphism in the CFI gene: Southern origin of East Asian-specific group H alleles
    Isao Yuasa; Feng Jin; Shinji Harihara; Aya Matsusue; Junko Fujihara; Haruo Takeshita; Atsushi Akane; Kazuo Umetsu; Naruya Saitou; Prasanta K. Chattopadhyay
    LEGAL MEDICINE, Sep. 2013, Refereed
  • A hypervariable STR polymorphism in the CFI gene: Mutation rate and no linkage disequilibrium with FGA
    Isao Yuasa; Nori Nakayashiki; Kazuo Umetsu; Hiroaki Nishimukai; Aya Matsusue; Koji Dewa
    Legal Medicine, May 2013, Refereed
  • Diagnostic implications of urinary liver-type fatty acid-binding protein and 8-hydroxy-2 '-deoxyguanosine in forensic autopsy cases
    Masayuki Kashiwagi; Tomoko Sugimura; Aya Matsusue; Kenji Hara; Brian Waters; Shin-ichi Kubo
    LEGAL MEDICINE, May 2013, Refereed
  • Application of high-throughput chiral analysis of amphetamines by GC–MS to whole blood specimens
    Fujii H; Hara K; Kashiwagi M; Matsusue A; Waters B; Kubo S
    Forensic Toxicology, 2013, Refereed
  • Combination of a short middle-bore capillary column with a thicker stationary phase and a short narrow-bore separation column with a thinner stationary phase for the rapid screening of non-volatile drugs by gas chromatography–mass spectrometry
    Brian Waters; Kenji Hara; Masayuki Kashiwagi; Aya Matsusue; Tomoko Sugimura; Saiko Hamasato; Shin-ichi Kubo
    FORENSIC TOXICOLOGY, Jan. 2013, Refereed
  • Immunohistochemical investigation of the coma blister and its pathogenesis
    Masayuki Kashiwagi; Akiko Ishigami; Kenji Hara; Aya Matsusue; Brian Waters; Mio Takayama; Itsuo Tokunaga; Akiyoshi Nishimura; Shin-Ichi Kubo
    Journal of Medical Investigation, 2013, Refereed
  • アンモニアガス曝露による事故死例:皮膚損傷の免疫組織化学的検討
    TAKAYAMA Mio; KASHIWAGI Masayuki; HARA Kenji; MATSUSUE Aya; WATERS Brian; TAKAMOTO Mutsuo; KUBO Shin-Ichi
    法医学の実際と研究, 2013
  • An autopsy case of sudden unexpected nocturnal death syndrome with R1193Q polymorphism in the SCN5A gene
    Aya Matsusue; Masayuki Kashiwagi; Kenji Hara; Brian Waters; Tomoko Sugimura; Shin-ichi Kubo
    LEGAL MEDICINE, Nov. 2012, Refereed
    Lead
  • 覚醒剤による腎障害:法医学の立場から
    久保 真一; 石上 安希子; 松末 綾; 徳永 逸夫
    日本臨床 新領域別症候群シリーズ, 2012, Refereed
  • Renal immunohistochemical investigation for the differentiation of the cause of multiple trauma fatalities
    Tomoko Sugimura; Elaine Lu Wang; Masayuki Kashiwagi; Kenji Hara; Aya Matsusue; Brian Waters; Shin-ichi Kubo
    LEGAL MEDICINE, Jan. 2012, Refereed
  • Phenotype prediction of mutations identified in rhabdomyolysis-associated genes in forensic autopsy cases of methamphetamine abusers
    Matsusue A; Hara K; Kashiwagi M; Waters B; Sugimura T; Kubo SI
    TIAFT BULLETIN, 2012
    Lead
  • Genetic analysis of the rhabdomyolysis-associated genes in forensic autopsy cases of methamphetamine abusers
    Aya Matsusue; Kenji Hara; Masayuki Kashiwagi; Mitsuyoshi Kageura; Tomoko Sugimura; Shin-ichi Kubo
    LEGAL MEDICINE, Jan. 2011, Refereed
    Lead
  • 胸郭多発骨折の成傷機序の判断に苦慮したダム湖内浮游死体の一剖検例
    柏木正之; 久保真一; 高本睦夫; 杉村朋子; 原 健二; 松末 綾; ウォーターズ ブライアン
    法医学の実際と研究, 2011, Refereed
  • A Japanese-specific allele in the GALNT11 gene
    Isao Yuasa; Kazuo Umetsu; Aya Matsusue; Hiroaki Nishimukai; Shinji Harihara; Yasuo Fukumori; Naruya Saitou; Feng Jin; Prasanta K. Chattopadhyay; Lotte Henke; Juergen Henke
    LEGAL MEDICINE, Jul. 2010, Refereed
  • Diagnostic approach to drug-screening tests for fatal diabetic ketoacidosis: Forensic autopsy of a methamphetamine abuser
    Masayuki Kashiwagi; Kenji Hara; Zhao Liu; Mitsuyoshi Kageura; Aya Matsusue; Tomoko Sugimura; Shin-ichi Kubo
    LEGAL MEDICINE, Jul. 2010, Refereed
  • Distinct breakpoints in two cases with deletion in the Yp11.2 region in Japanese population
    Reiko Kumagai; Yoshitoshi Sasaki; Takuya Tokuta; Hitoshi Biwasaka; Aya Matsusue; Yasuhiro Aoki; Koji Dewa
    HUMAN GENETICS, Mar. 2010, Refereed
  • Application of the drowning index to actual drowning cases
    Tomoko Sugimura; Masayuki Iashiwagi; Aya Matsusue; Kenji Hara; Mitsuyoshi Kageura; Shin-ichi Kubo
    LEGAL MEDICINE, Mar. 2010, Refereed
  • An autopsy case of rhabdomyolysis related to vegetamin and genetic analysis of the rhabdomyolysis-associated genes
    Aya Matsusue; Kenji Nara; Mitsuyoshi Kageura; Masayuki Kashiwagi; Wang Lu; Akiko Ishigami; Takako Gotohda; Itsuo Tokunaga; Akiyoshi Nisimura; Tomoko Sugimura; Shin-ichi Kubo
    JOURNAL OF FORENSIC AND LEGAL MEDICINE, Jan. 2010, Refereed
    Lead
  • Genetic analysis of rhabdomyolysis-associated genes: An autopsy case of methamphetamine-related hyperthermia and acidosis.
    Matsusue A; Ishigami A; Hara K; Kashiwagi M; Kageura M; Sugimura T; Kubo S
    Acta Medicinae Legalis et Socialis, 2010
    Lead
  • 誤挿入した胃瘻チューブから投与された栄養剤により汎発性腹膜炎で死亡した1剖検例
    杉村朋子; 柏木正之; 松末 綾; 高本睦夫; 原 健二; 影浦光義; 久保真一
    法医病理, 2010
  • 特異な蚕食を認めた水中死体の1剖検例:ニセスナホリムシによる死後損壊
    柏木正之; 杉村朋子; 原 健二; 松末 綾; 影浦光義; 久保真一
    法医学の実際と研究, 2010
  • 覚醒剤による興奮錯乱状態の為に鎮静衣で拘束されその約13時間後に死亡した一例
    大島 徹; 米満孝聖; 松末 綾; 原 健二; 久保真一; 大谷真紀; 美作宗太郎
    法医学の実際と研究, 2010
  • Analysis of acetylene in blood and urine using cryogenic gas chromatography-mass spectrometry
    Masayuki Kashiwagi; Kenji Hara; Hiroshi Fujii; Mitsuyoshi Kageura; Mutsuo Takamoto; Aya Matsusue; Tomoko Sugimura; Shin-ichi Kubo
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, Sep. 2009, Refereed
  • High throughput chiral analysis of urinary amphetamines by GC-MS using a short narrow-bore capillary column
    Hiroshi Fujii; Kenji Hara; Mitsuyoshi Kageura; Masayuki Kashiwagi; Aya Matsusue; Shin-ichi Kubo
    FORENSIC TOXICOLOGY, Jul. 2009, Refereed
  • ADAM33 genetic polymorphisms and risk of atopic dermatitis among Japanese children
    Aya Matsusue; Chikako Kiyohara; Keiko Tanaka; Satoshi Sasaki; Yoshihiro Miyake
    CLINICAL BIOCHEMISTRY, Apr. 2009, Refereed
    Lead
  • Genetic analysis of ryanodine receptor 1 gene and carnitine palmitoyltransferase II gene: An autopsy case of neuroleptic malignant syndrome related to vegetamin
    Aya Matsusue; Kenji Hara; Mitsuyoshi Kageura; Masayuki Kashiwagi; Wang Lu; Akiko Ishigami; Takako Gotohda; Itsuo Tokunaga; Akiyoshi Nisimura; Tomoko Sugimura; Shin-ichi Kubo
    Legal Medicine, Apr. 2009, Refereed
    Lead
  • An autopsy case of suicide by acetylene explosion: a case report
    Masayuki Kashiwagi; Kenji Hara; Mutsuo Takamoto; Mitsuyoshi Kageura; Aya Matsusue; Tomoko Sugimura; Shin-ichi Kubo
    MEDICINE SCIENCE AND THE LAW, Apr. 2009, Refereed
  • Solid-phase microextraction for amphetamines in solid tissues: washing the homogenates with ethyl ether enables their measurements by GC-MS after heptafluorobutyryl derivatization
    Kenji Hara; Masayuki Kashiwagi; Mitsuyoshi Kageura; Aya Matsusue; Shin-ichi Kubo
    FORENSIC TOXICOLOGY, Feb. 2009, Refereed
  • 無人のマニュアル・トランスミッション車により轢過された一剖検例
    柏木正之; 植田豊; 原 健二; 影浦光義; 松末 綾; 杉村朋子; 久保真一
    法医学の実際と研究, 2009
  • 悪性症候群の剖検診断項目の検討:ベゲタミン服用の1剖検例
    久保真一; 王 璐; 原 健二; 松末 綾; 影浦光義; 石上安希子; 徳永逸夫; 柏木正之; 杉村朋子; 西村明儒
    法医病理, 2009
  • Molecular basis of complement factor I (CFI) polymorphism: one of two polymorphic suballeles responsible for CFI A is Japanese-specific
    Isao Yuasa; Mayumi Nakagawa; Kazuo Umetsu; Shinji Harihara; Aya Matsusue; Hiroaki Nishimukai; Yasuo Fukumori; Naruya Saitou; Kyung Sook Park; Feng Jin; Gerard Lucotte; Prasanta K. Chattopadhyay; Lotte Henke; Juergen Henke
    JOURNAL OF HUMAN GENETICS, Dec. 2008, Refereed
  • Haplotype analysis of seven Y-STRs (eleven loci) in two Japanese populations
    Isao Yuasa; Yoshito Irizawa; Hiroaki Nakamura; Aya Matusue; Kazuo Umetsu
    Legal Medicine, Nov. 2008, Refereed
  • Population genetics of 17 Y-chromosomal STR loci in Japanese
    Masaki Hashiyada; Kazuo Umetsu; Isao Yuasa; Akiyoshi Tamura; Aya Matsusue; Koichi Suzuki; Seiichi Kashimura; Masato Funayama
    Forensic Science International: Genetics, Sep. 2008, Refereed
  • Dual examinations for identification of urine as being of human origin and for DNA-typing from small stains of human urine
    Takehiko Nakazono; Seiich Kashimura; Yasuhiko Hayashiba; Kenji Hara; Aya Matsusue; Christa Augustin
    JOURNAL OF FORENSIC SCIENCES, Mar. 2008, Refereed
  • Allele frequencies of a SNP and a 27-bp deletion that are the determinant of earwax type in the ABCC11 gene
    Takashi Kitano; Isao Yuasa; Kentaro Yamazaki; Nori Nakayashiki; Aya Miyoshi; Kyung Sook Park; Kazuo Umetsu
    Legal Medicine, Mar. 2008, Refereed
  • 防腐処理なしに人為的につくられたミイラ化死体の一剖検例
    柏木正之; 高宮紘士; 高本睦夫; 原 健二; 影浦光義; 松末 綾; 久保真一
    法医学の実際と研究, 2008
  • OCA2 481Thr, a hypofunctional allele in pigmentation, is characteristic of northeastern Asian populations
    Yuasa I; Umetsu K; Harihara S; Miyoshi A; Saitou N; Park KS; Dashnyam B; Jin F; Lucotte G; Chattopadhyay PK; Henke L; Henke J
    J Hum Genet, 2007, Refereed
  • Distribution of two Asian-related coding SNPs in the MC1R and OCA2 genes
    Yuasa I; Umetsu K; Harihara S; Kido A; Miyoshi A; Saitou N; Dashnyam B; Jin F; Lucotte G; Chattopadhyay PK; Henke L; Henke J
    Biochem Genet, 2007, Refereed
  • Ligand-activated PPARbeta efficiently represses the induction of LXR-dependent promoter activity through competition with RXR
    Matsusue K; Miyoshi A; Yamano S; Gonzalez FJ
    Mol Cell Endocrinol, 2006, Refereed
  • Two simple methods for enantiomeric analyses of urinary amphetamines by GC/MS using deuterium-labeled L-amphetamines as internal standards
    Liu Z; Hara K; Kashimura S; Liu J; Fujii H; Kashiwagi M; Miyoshi A; Yanai T; Kageura M
    Forensic Toxicol, 2006, Refereed
  • Rapid GC-MS analysis of methamphetamine and its metabolites in urine —application of a short narrow-bore capillary column to GC-MS
    Fujii H; Hara K; Kashimura S; Kageura M; Kashiwagi M; Miyoshi A; Ikeda S
    J Chromatogr B Analyt Technol Biomed Life Sci, 2006, Refereed
  • Rapid analysis of acetaminophen in serum by gas chromatography—mass spectrometry with extractive derivatization using a diatomaceous earth tube
    Hara K; Kashimura S; Yanai T; Kashiwagi M; Miyoshi A; Kageura M
    Forensic Toxicol, 2006, Refereed
  • Distribution of the F374 allele of the SLC45A2 (MATP) gene and founder-haplotype analysis
    Yuasa I; Umetsu K; Harihara S; Kido A; Miyoshi A; Saitou N; Dashnyam B; Jin F; Lucotte G; Chattopadhyay PK; Henke L; Henke J
    Ann Hum Genet, 2006, Refereed
  • Multiplex amplified product-length polymorphism analysis of 36 mitochondrial single-nucleotide polymorphisms for haplogrouping of East Asian populations
    Umetsu K; Tanaka M; Yuasa I; Saitou N; Takeyasu T; Fuku N; Naito E; Ago K; Nakayashiki N; Miyoshi A; Kashimura S; Watanabe G; Osawa M
    Electrophoresis, 2005, Refereed
  • Successful DNA typing of urine stains using a DNA purification kit following dialfiltration
    Nakazono T; Kashimura S; Hayashiba Y; Hara K; Miyoshi A
    Journal of Forensic Sciences, 2005, Refereed
  • Detection of 4-hydroxymethamphetamine-O-glucuronide from urine by gas chromatography-mass spectrometry using the urease-trimethylsilylation method
    Fujii H; Kashimura S; Hara K; Miyoshi A; Kashiwagi M; Kageura M; Hamanaka T
    Jpn J Forensic Toxicol, 2004
  • Simultaneous expression of Guinea pig udp-glucuronosyltransferase 2b21 (ugt2b21) and 2b22 in cos-7 cells enhances ugt2b21-catalyzed chloramphenicol glucuronidation
    Ishii Y; Miyoshi A; Maji D; Yamada H; Oguri K
    Drug Metabolism and Disposition, 2004, Refereed
  • Multiplex amplified product-length polymorphism analysis for rapid detection of human mitochondrial DNA variations
    Umetsu K; Tanaka M; Yuasa I; Saitou N; Takeyasu T; Fuku N; Naito E; Ago K; Nakayashiki N; Miyoshi A; Kashimura S; Watanabe G; Osawa M
    Electrophoresis, 2001, Refereed
  • Simultaneous expression of guinea pig UDP-glucuronosyltransferase 2B21 and 2B22 in COS-7 cells enhances UGT2B21-catalyzed morphine-6-glucuronide formation
    Ishii Y; Miyoshi A; Watanabe R; Tsuruda K; Tsuda M; Yamaguchi-Nagamatsu Y; Yoshisue K; Tanaka M; Maji D; Ohgiya S; Oguri K
    Molecular Pharmacology, 2001, Refereed
■ MISC
  • 覚醒剤摂取症例におけるCOMT遺伝子多型と脳脊髄液中ドパミン濃度の関連
    松末 綾; 石川 隆紀; 道上 知美; Waters Brian; 原 健二; 高山 みお; 池松 夏紀; 柏木 正之; 久保 真一
    日本法医学雑誌, Dec. 2017
  • 覚醒剤中毒死症例におけるDRD2/ANKK1遺伝子多型解析
    松末 綾; 石川 隆紀; 道上 知美; Waters Brian; 原 健二; 高山 みお; 池松 夏紀; 柏木 正之; 久保 真一
    日本法医学雑誌, May 2017
■ Books and other publications
  • Genetics in forensic science
    Matsusue A; Kubo S
    2019
■ Lectures, oral presentations, etc.
  • 体液中覚醒剤濃度とCYP2D6遺伝子多型の関連.
    松末 綾; 石川隆紀; 池田知哉; 道上知美; Brian Waters; 原 健二; 髙山みお; 池松夏紀; 柏木正之; 久保真一
    第67回日本法医学会学術九州地方集会, 2017
  • 覚醒剤摂取症例におけるCOMT遺伝子多型と脳脊髄液中カテコラミン濃度の関連.
    松末 綾; 久保真一; 道上知美; Brian Waters; 原 健二; 柏木正之; 髙山みお; 池松夏紀; 石川隆紀
    第35回日本ヒト細胞学会学術集会, 2017
  • 覚醒剤中毒死症例におけるDRD2/ANKK1遺伝子多型解析.
    松末 綾; 石川隆紀; 道上知美; Brian Waters; 原 健二; 髙山みお; 池松夏紀; 柏木正之; 久保真一
    第101次日本法医学会学術全国集会, 2017
  • Association between dopamine levels in cerebrospinal fluid and catechol-O-methyltransferase gene polymorphisms in forensic autopsy cases of methamphetamine abusers.
    Aya Matsusue; Takaki Ishikawa; Tomomi Michiue; Brian Waters; Kenji Hara; Masayuki Kashiwagi; Mio Takayama; Natsuki Ikematsu; Shin-ichi Kubo
    10th International Symposium on Advances in Legal Medicine (ISALM), 2017
  • 中国人特異的アレルの検索.
    松末 綾; 梅津和夫; 飯野守男; 湯浅 勲
    日本DNA多型学会第25回学術集会, 2016
  • 覚醒剤摂取症例におけるCOMT遺伝子多型と脳脊髄液中ドパミン濃度の関連.
    松末 綾; 石川隆紀; 道上知美; Brian Waters; 原 健二; 髙山みお; 池松夏紀; 柏木正之; 久保真一
    第66回日本法医学会学術九州地方集会, 2016
  • The frequencies of the R1193Q polymorphism in the SCN5A gene in Asian, German and African populations.
    Aya Matsusue; Isao Yuasa; Kazuo Umetsu; Nori Nakayashiki; Masayuki Kashiwagi; Kenji Hara; Brian Waters; Mio Takayama; Shin-ichi Kubo
    9th International Symposium on Advances in Legal Medicine (ISALM), 2014
  • アジア人,ドイツ人並びにアフリカ人集団におけるSCN5A遺伝子R1193Q変異の頻度調査.
    松末 綾; 湯浅 勲; 梅津和夫; 中屋敷 徳; 出羽 厚二; 柏木正之; 原 健二; Brian Waters; 髙山みお; 髙本睦夫; 久保真一
    第15回日本法医学会学術北日本地方集会, 2014
  • 乳幼児突然死症例におけるSCN5A、RYR2、CPTII、VLCAD遺伝子の変異探索
    松末 綾; 柏木正之; 原 健二; Brian Waters; 高本睦夫; 久保真一
    第19回日本SIDS・乳幼児突然死予防学会, 2013
  • 成人及び乳幼児の突然死剖検例における遺伝性不整脈疾患の原因遺伝子変異の探索
    第5回福岡県医学会総会, 2013
  • The frequencies of R1193Q polymorphism in the SCN5A gene in Japanese and German populations
    11th Indo Pacific Association of Law, Medicine and Science Congress, 2013
  • 日本人並びにドイツ人におけるSCN5A遺伝子R1193Q変異の頻度調査
    第63回日本法医学会学術九州地方集会, 2013
  • 心臓突然死剖検例におけるSCN5A遺伝子の変異探索
    松末 綾; 柏木正之; 原 健二; Brian Waters; 杉村朋子; 高本睦夫; 久保真一
    第96次日本法医学会総会, 2012
  • 乳幼児突然死症例におけるSCN5A、RYR2、CPTII、VLCAD遺伝子の変異探索
    松末 綾; 柏木正之; 原 健二; Brian Waters; 高本睦夫; 久保真一
    第62回日本法医学会学術九州地方集会, 2012
  • Phenotype prediction of mutations identified in rhabdomyolysis-associated genes in forensic autopsy cases of methamphetamine abusers.
    Matsusue A; Hara K; Kashiwagi M; Waters B; Sugimura T; Kubo S
    50th Annual Meeting of the International Association of Forensic Toxicologists, 2012
  • 心臓突然死剖検例におけるSCN5A遺伝子の変異探索
    松末 綾; 柏木正之; 原 健二; ウォーターズ ブライアン; 杉村朋子; 高本睦夫; 久保真一
    第61回日本法医学会学術九州地方集会, 2011
  • Genetic analysis of the four rhabdomyolysis-associated genes in 18 forensic autopsy cases of methamphetamine abusers
    Matsusue A; Hara K; Kashiwagi M; Waters B; Sugimura T; Kubo S
    8th International Symposium Advances in Legal Medicine, 2011
  • 覚せい剤が検出された剖検例における横紋筋融解症関連遺伝子変異の解析
    松末 綾; 杉村 朋子; 原 健二; 柏木 正之; 高本 睦夫; 影浦 光義; 久保 真一
    第94次日本法医学会学術全国集会, 2010
  • Genetic analysis of rhabdomyolysis-associated genes and immunohistochemical study of myoglobin in the kidney in autopsy cases of methamphetamine abusers
    Aya Matsusue; Kenji Hara; Masayuki Kashiwagi; Mitsuyoshi Kageura; Tomoko Sugimura; Shin-ichi Kubo
    48th Annual Meeting of the International Association of Forensic Toxicologists, 2010
  • Genetic analysis of rhabdomyolysis-associated genes: an autopsy case of methamphetamine-related hyperthermia and acidosis.
    Matsusue A; Ishigami A; Hara K; Kashiwagi M; Kageura M; Sugimura T; Kubo S
    21st Congress of the International Academy of Legal Medicine, 2009
  • 横紋筋融解症におけるRYR1遺伝子変異の検討:ベゲタミン中毒の1剖検例
    松末 綾; 原 健二; 影浦光義; 柏木正之; Lu Wang; 石上安希子; 後藤田貴子; 徳永逸夫; 柏村征一; 久保真一
    第92次日本法医学会総会, 2008
  • アトピー性皮膚炎とADAM33遺伝子多型との関連
    松末 綾; 清原千香子; 田中景子; 佐々木敏; 三宅吉博
    第20回日本アレルギー学会春季臨床大会, 2008
  • 横紋筋融解症における遺伝学的背景の検討:ベゲタミン中毒の一剖検例(第3報)
    松末 綾; 原 健二; 影浦光義; 柏木正之; 杉村朋子; 久保真一
    第58回日本法医学会九州地方会, 2008
  • Genetic analysis of ryanodine receptor 1 gene and carnitine palmitoyltransferase II gene : An autopsy case of neuroleptic malignant syndrome related to vegetamin
    Matsusue A; Hara K; Kageura M; Kashiwagi M; Wang L; Ishigami A; Gotohda T; Tokunaga I; Sugimura T; Kubo S
    7th International Symposium on Advances in Legal Medicine, 2008
■ Affiliated academic society
  • 日本DNA多型学会
  • 日本法医学会
■ Research Themes
  • 覚醒剤の毒性発現の個人差に影響する遺伝的要因の解明
    日本学術振興会, 科学研究費助成事業, 基盤研究(C)
    福岡大学
    Apr. 2022 - Mar. 2025
  • 戦没者遺骨の身元特定に係るDNA鑑定の精度向上に関する研究
    厚生労働科学研究費補助金 行政政策研究分野 政策科学総合研究(政策科学推進研究)
    Apr. 2021 - Mar. 2024
  • 覚醒剤の毒性発現に関与する遺伝子の特定と死因究明への応用
    日本学術振興会, 科学研究費助成事業, 基盤研究(C)
    福岡大学
    Apr. 2019 - Mar. 2023
  • 尿毒素としての腸内細菌産生フェニルアセチルグルタミンの法医剖検診断の意義の解明
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C)
    Fukuoka University
    Apr. 2019 - Mar. 2023
  • 数時間前の飲酒の証明に挑戦する:新たな飲酒マーカー・腸管を経由した酒類成分の探索
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Research (Exploratory)
    Fukuoka University
    Jun. 2017 - Mar. 2019
  • 乳幼児突然死の原因究明にむけて:遺伝的背景の検討と新たな遺伝子診断法の開発
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C)
    Fukuoka University
    Oct. 2015 - Mar. 2018
  • 心臓突然死の迅速な遺伝子診断法の開発:致死性不整脈原因遺伝子変異の探索のために
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C)
    Fukuoka University
    Apr. 2012 - Mar. 2016
  • ヒト特異性の高いmRNAを標的とした血液証明法の開発:個人識別の新たな展開
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research
    Fukuoka University
    Apr. 2013 - Mar. 2015
  • 死因究明のための体組織からの高感度・迅速薬物スクリーニング・システムの開発
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C)
    Fukuoka University
    Apr. 2012 - Mar. 2015
  • 心臓突然死の新たな診断アプローチ:致死性不整脈原因遺伝子変異の迅速検出法の検討
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B)
    Fukuoka University
    2010 - 2011
  • 薬毒物関連死の剖検診断の新たな展開に向けて:遺伝学的背景の検討
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B)
    Fukuoka University
    2009 - 2011
  • 薬毒物に起因する横紋筋融解症の新規マーカー遺伝子の同定及び遺伝子診断法の確立
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B)
    Fukuoka University
    2008 - 2009
  • 死体尿中スペルミン検出の意義づけに関する研究
    Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B)
    Fukuoka University
    2001 - 2003
■ Social Contribution Activities
  • 戦没者遺骨のDNA鑑定人会議委員
    organizing_member
    厚生労働省