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Last Updated :2024/04/12

小玉 正太

医学科
教授

プロフィールRESEARCH EXPERIENCE: 1996-2000: Graduate school student, Transplantation Laboratory (Director: Associate Professor, Yohichi Yasunami, M.D., D.M.S.) Department of cell transplantation and regenerative medicine, Fukuoka University, School of Medicine, Fukuoka, Japan. 2000-2003: Postdoctoral Fellow, Immunobiology Laboratory (Director: Associate Professor, Denise L. Faustman, M.D., Ph.D.) Department of Immunobiology Laboratory, Massachusetts General Hospital, Harvard Medical School, MA, U.S.A.

研究者情報

■ 学位
  • Certification of Medical License and Doctor of Philosophy, Education International (U.S.A.)
■ 研究キーワード
  • 4 膵島移植 膵島研究
  • 3 移植免疫
  • 2 幹細胞研究
  • 1 再生医学
■ 研究分野
  • ライフサイエンス, 細胞生物学, 再生医学、幹細胞研究、移植免疫、膵島研究

経歴

■ 経歴
  • 2007年 - 2009年
    Faculty member at Harvard Medical School, Assistant Professor. Harvard titles are continued in MGH and BWH.
  • 2009年
    President directed Associate Professor, Department of Regenerative Medicine & Transplantation, Faculty of Medicine, Fukuoka University
  • 2009年
    President directed Associate Professor, Department of Regenerative Medicine & Transplantation, Faculty of Medicine, Fukuoka University
  • 2005年 - 2007年
    Faculty member at Harvard Medical School, Instructor in Anesthesiology. Faculty member at Brigham and Women’s Hospital, Research Associate. Faculty member at Massachusetts General Hospital, Assista
  • 2003年 - 2005年
    Faculty member at Harvard Medical School, Instructor in Medicine. Faculty member at Massachusetts General Hospital, Assistant in Biology.
  • 2000年 - 2003年
    Postdoctoral Fellow, Immunobiology Laboratory Department of Immunobiology Laboratory, Massachusetts General Hospital, Harvard Medical School, MA, U.S.A.
  • 1995年 - 1996年
    Chief Resident in Gastroenterology Surgery, Aichi Cancer Center Hospital, Aichi, Japan.
  • 1994年 - 1995年
    Resident in Gastroenterology Surgery, Aichi Cancer Center Hospital, Aichi, Japan.
  • 1993年 - 1994年
    Surgical staff in Itoshima Hospital of the Japan Medical Association, Fukuoka, Japan.
  • 1992年 - 1993年
    Surgical staff in Hakujuji Hospital, Fukuoka, Japan.
  • 1991年 - 1992年
    Senior Resident in Anesthesiology and Intensive Care Unit, Kouseikan prefectural hospital, Saga, Japan.
  • 1990年 - 1991年
    Junior Resident in Surgery I, Cardiovascular surgery and Radiology, Fukuoka University Hospital, Fukuoka ,Japan.
■ 学歴
  • 2000年
    福岡大学, 医学研究科, Transplantation and Immunology
■ 委員歴
  • 2013年
    Editorial Board Member
  • 2013年
    Editorial Board Member, #6. JSM Regenerative Medicine: Editorial Board Member (http://www.jscimedcentral.com/Regenerative/index.php) JSciMed Central (http://www.jscimedcentral.com/Regenerative/editors.php), USA
  • 2013年
    Editorial Board Member, #2. Islets: Editorial Board Member (http://www.landesbioscience.com/journals/islets/editorialboard/) Landes Bioscience (http://www.landesbioscience.com), USA
  • Editorial Board Member
  • Editorial Board Member, #5. Advances in Medicine: Editorial Board Member (http://www.hindawi.com/journals/amed/editors/transplantation/ ) Hindawi Publishing Corporation (http://www.hindawi.com/journals/amed/), USA
  • Editorial Board Member, #4. Journal of Regenerative Medicine (JRGM): Editorial Board Member (http://www.scitechnol.com/editorialboardJRGM.php) SciTechnol, International Publisher of Science, Technology and Medicine (http://www.sciepub.com), USA
  • Editorial Board Member, #3. Current Tissue Engineering: Editorial Board Member (http://benthamscience.com/cte/EBM.htm) Bentham Science Publishers (http://www.benthamscience.com/Advertising.htm), USA
  • Editorial Board Member, #1. American Journal of Medical and Biological Research (AJMBR): Editorial Board Member (http://www.sciepub.com/journal/AJMBR/EditorialBoard) Science and Education Publishing (http://www.sciepub.com), USA

研究活動情報

■ 受賞
  • 2004年03月
    Sjogren's Syndrome Foundation, Research Award
    Research Award with Grant
  • 2004年
    Eboshi-kai presented, Young Investigator Award
    その他の賞
■ 論文
  • Possibility of adiponectin use to improve islet transplantation outcomes.
    坂田直昭; 吉松軍平; 知念澄志; 川上 亮; 小玉 正太
    Scientific Reports, 2022年01月10日, 査読有り
  • Therapeutic effects of acylated ghrelin-specific receptor GHS-R1a antagonist in islet transplantation
    Kiyoshi Chinen; Naoaki Sakata; Gumpei Yoshimatsu; Masafumi Nakamura; Shohta Kodama
    Scientific Reports, 2021年10月28日, 査読有り
  • The Roles of Collagen in Islet Transplantation
    Naoaki Sakata; Gumpei Yoshimatsu; Shohta Kodama
    OBM Transplantation, 2020年11月27日, 査読有り
  • White Adipose Tissue as a Site for Islet Transplantation
    Naoaki Sakata; Gumpei Yoshimatsu; Shohta Kodama
    Transplantology, 2020年09月01日, 査読有り
  • Changes in Immunological Status in Patients With Metastatic Colorectal Cancer Treated With First-line Chemoimmunotherapy
    山田 哲平; 吉松軍平; 吉田 陽一郎; 愛洲 尚哉; 薦野 晃; 松本 芳子; 長野 秀紀; 吉村 文博; 坂田 直昭; 小玉 正太; 長谷川 傑
    Anticancer Research, 2020年08月
  • Inhibition of NLRP3 inflammasome by MCC950 improves the metabolic outcome of islet transplantation by suppressing IL‑1β and islet cellular death
    Taisuke Matsuoka; Gumpei Yoshimatsu; Naoaki Sakata; Ryo Kawakami; Tomoko Tanaka; Teppei Yamada; Yoichiro Yoshida; Suguru Hasegawa; Shohta Kodama
    Sci Rep, 2020年, 査読有り
  • Islet and Pancreas Autotransplantations for Total Pancreatectomy
    Naoaki Sakata; Gumpei Yoshimatsu; Shohta Kodama
    OBM Transplantation, 2019年04月01日, 査読有り
  • Regenerative and Transplantation Medicine: Cellular Therapy Using Adipose Tissue-Derived Mesenchymal Stromal Cells for Type 1 Diabetes Mellitus.
    TAKAHASHI Hiroyuki; SAKATA Naoaki; YOSHIMATSU GUMPEI; HASEGAWA Suguru; KODAMA SHOHTA
    J Clin Med, 2019年02月15日, 査読有り
  • Evaluation of vascular pain in patients with colorectal cancer receiving peripheral venous chemotherapy with or without oxaliplatin.
    Matsuoka T; Yoshida Y; Aisu N; Yamada T; Mogi A; Komono A; Sakamoto R; Kojima D; Yoshimatsu G; Kiyomi F; Kodama S; Hasegawa S
    Sci Rep, 2019年02月12日, 査読有り
  • Current Consensus: Cellular Therapy Using Adipose Tissue-Derived Regenerative and Transplantation Medicine: Cellular Therapy Using Adipose Tissue-Derived Mesenchymal Stem Cells for Type 1 Diabetes Mellitus
    Hiroyuki Takahashi; Naoaki Sakata; Gumpei Yoshimatsu; Suguru; Hasegawa; Shohta Kodama
    Journal of Clinical Medicine, 2019年, 査読有り
  • The Spleen as an Optimal Site for Islet Transplantation and a Source of Mesenchymal Stem Cells.
    Sakata N; Yoshimatsu G; Kodama S
    Int J Mol Sci, 2018年05月07日, 査読有り
  • Clinical study on the medical value of combination therapy involving adoptive immunotherapy and chemotherapy for stage IV colorectal cancer (COMVI Ⅳ study)
    Yoshida Y; Naito M; Yamada T; Aisu N; Daibo K; Mera T; Tanaka T; Naito K; Yasumoto K; Kamigaki T; Gotoh S; Kodama S; Yamashita Y; Hasegawa H
    Anticancer Research, 2017年07月, 査読有り
  • Hepatectomy for Liver Metastasis of Colorectal Cancer After Adoptive Chemoimmunotherapy Using Activated αβT-cells
    Ishii F; Yoshida Y; Yamauchi Y; Aisu N; Kojima D; Mera T; Kato D; Tanaka T; Naito K; Yasumoto K; Kamigaki T; Goto S; Hamada Y; Nimura S; Kodama S; Hasegawa S
    Anticancer Research, 2017年07月, 査読有り
  • Spleen is an ideal site for inducing expansion of transplanted islet grafts in mice
    Itoh T; Nishinakamura H; Kumano K; Takahashi H; Kodama S
    PLOS ONE, 2017年, 査読有り
  • EphA2-targeted cancer therapy obtained by antibody screening method
    Tanaka T; Yamada H; Nogami R; Kuroki M; Hamada H; Kodama S; Tamura K; Takamatsu Y
    Transl Oncol, 2017年, 査読有り
  • CD44 Promotes Inflammation and Extracellular Matrix Production During Arteriovenous Fistula Maturation.
    Hanisch J; Bai H., Hu H; Protack CD; Hall MR; Schardt JS; Jay SM; Madri JA; Kodama S; Dardik A
    Arterioscler Thromb Vasc Biol, 2017年, 査読有り
  • Islet-derived damage-associated molecular pattern molecule contributes to immune responses following microencapsulated neonatal porcine islet xenotransplantation in mice
    Takeshi Itoh; Yuko Hata; Hitomi Nishinakamura; Kenjiro Kumano; Hiroyuki Takahashi; Shohta Kodama
    XENOTRANSPLANTATION, 2016年09月, 査読有り
  • Pretreatment of donor islets with papain improves allograft survival without systemic immunosuppression in mice
    Kenjiro Kumano; Hitomi Nishinakamura; Toshiyuki Mera; Takeshi Itoh; Hiroyuki Takahashi; Toshiyoshi Fujiwara; Shohta Kodama
    ISLETS, 2016年, 査読有り
  • An extremely weak electric current system induces anti-apoptotic effects and anti-necrotic effects in living cells.
    Kojima D; Nishinakamura H; Itoh T; Kodama S
    Current Tissue Engineering, 2014年10月, 査読有り
  • GM-CSF Treated F4/80(+) BMCs Improve Murine Hind Limb Ischemia Similar to M-CSF Differentiated Macrophages
    Go Kuwahara; Hitomi Nishinakamura; Daibo Kojima; Tadashi Tashiro; Shohta Kodama
    PLOS ONE, 2014年09月, 査読有り
  • HMGB1-mediated early loss of transplanted islets is prevented by anti-IL-6R antibody in mice.
    Itoh T; Nitta T; Nishinakamura H; Kojima D; Mera T; Ono J; Kodama S; Yasunami Y
    PANCREAS, 2014年07月, 査読有り
  • Edaravone, a Free Radical Scavenger, Accelerates Wound Healing in Diabetic Mice
    Naito R; Nishinakamura H; Watanabe T; Nakayama J; Kodama S; esponding Aut
    WOUNDS, 2014年06月, 査読有り
  • Treating salivary gland hypofunction at both initial and advanced stages of Sjögren’s-like disease: a comparative study of bone marrow- versus spleen-cell therapy with a one-year monitoring period.
    Khalili S; Faustman DL; Liu Y; Sumita Y; Blank D; Peterson A; Kodama S; Tran SD
    Cytotherapy, 2014年01月, 査読有り
  • Vascular endothelial growth factor-C derived from CD11b(+) cells induces therapeutic improvements in a murine model of hind limb ischemia
    Go Kuwahara; Hitomi Nishinakamura; Daibo Kojima; Tadashi Tashiro; Shohta Kodama
    JOURNAL OF VASCULAR SURGERY, 2013年04月, 査読有り
  • Pretreatment of donor islets with the Na+/Ca2+ exchanger inhibitor improves the efficiency of islet transplantation
    Mera T; Itoh T; Kita S; Kodama S; Kojima D; Nishinakamura H; Okamaoto K; Ohkura M; Nakai J; Iyoda T; Iwamoto T; Matsuda T; Baba A; Omori K; MullenY; Ono L; Watari H; Taniguchi M; Yasunami T
    Am J Transplant, 2013年, 査読有り
  • Mesenchymal Stromal Cells Improve Salivary Function and Reduce Lymphocytic Infiltrates in Mice with Sjögren's-Like Disease.
    Khalili S; Liu Y; Kornete M; Roescher N; Kodama S; Peterson A; Piccirillo CA; Tran SD
    PLoS ONE, 2012年06月, 査読有り
  • Two-Layered Tissue-Engineered Urethra Using Oral Epithelial and Muscle-Derived Cells.
    Mikami H; Kuwahara G; Nakamura N; Yamato M; Tanaka M; Kodama S; A
    J Urology, 2012年05月, 査読有り
  • Prevention of High-Mobility Group Box 1-Mediated Early Loss of Transplanted Mouse Islets in the Liver by Antithrombin III
    Daibo Kojima; Toshiyuki Mera; Hitomi Nishinakamura; Takeshi Itoh; Takako Ogata; Nobuhide Matsuoka; Shohta Kodama; Yohichi Yasunami
    TRANSPLANTATION, 2012年05月, 査読有り
  • Oriented Collagen Scaffolds for Tissue Engineering
    Yoshihiro Isobe; Toru Kosaka; Go Kuwahara; Hiroshi Mikami; Taro Saku; Shohta Kodama
    MATERIALS, 2012年03月, 査読有り
  • IKKβ regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways
    Ashida N; Banerjee SS; Kodama S; Foo SY; Coggins M; Spencer JA; Zamiri P; Shen D; Li L; Sciuto T; Dvorak A; Gerszten RE; Lin CP; Karin M; Rosenzweig A
    Nature Communications, 2011年05月, 査読有り
  • Proteomics identifies multipotent and low oncogenic risk stem cells of the spleen.
    Dieguez-Acu; a F; Kodama S; Okubo Y; Paz AC; Gygi SP; Faustman DL
    Int J Biochem Cell Biol., 2009年12月, 査読有り
  • Engineering functional islets from cultured cells.
    Kodama S; Kojima K; Furuta S; Chambers M; Paz AC., Vacanti; CA; Corresponding Au
    Tissue Eng Part A, 2009年, 査読有り
  • Fetal Hox11 expression patterns predict defective target organs: a novel link between developmental biology and autoimmunity
    Anna Lonyai; Shohta Kodama; Douglas Burger; Denise L. Faustman
    IMMUNOLOGY AND CELL BIOLOGY, 2008年06月
  • The promise of Hox11+stem cells of the spleen for treating autoimmune diseases
    A. Lonyai; S. Kodama; D. Burger; M. Davis; D. L. Faustman
    HORMONE AND METABOLIC RESEARCH, 2008年02月, 査読有り
  • Bioengineered three-layered robust and elastic artery utilizing hemodynamically-equivalent pulsatile bioreactor.
    Iwasaki K; Kojima K; Kodama S; Paz AP; Chamber M; Umezu M; Vacanti CA
    Circulation, 2008年, 査読有り
  • Lidocaine inhibits NIH-3T3 cell multiplication by increasing expression of cyclin-depenedent kinase inhibitor 1A (p21).
    Desai SP; Kojima K; Vacanti CA; Kodama S; g; Au
    Anesth Analg, 2008年
  • VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites
    Satoshi Hirakawa; Lawrence F. Brown; Shohta Kodama; Karri Paavonen; Kari Alitalo; Michael Detmar
    BLOOD, 2007年02月, 査読有り
  • Reversal of Sjögren’s-like syndrome in non-obese diabetic mice.
    Tran SD; Kodama S; Lodde BM; Szalayova I; Key S; Khalili S; Faustman DL; Mezey E; T.S; K.S. contributed equally to this wor
    Ann Rheum Dis, 2007年, 査読有り
  • Diabetes reversal in NOD mice.
    Faustman DL; Tran SD; Kodama S; Lodde BM; Szalayova I; Key S; Toth ZE; Mezey E
    Science, 2006年, 査読有り
  • Methods to characterize lymphoid apoptosis in a murine model of autoreactivity
    WM Kuhtreiber; S Kodama; DE Burger; EA Dale; DL Faustman
    JOURNAL OF IMMUNOLOGICAL METHODS, 2005年11月, 査読有り
  • Characterization of mouse spleen cells by subtractive proteomics
    FJ Dieguez-Acuna; SA Gerber; S Kodama; JE Elias; SA Beausoleil; D Faustman; SP Gygi
    MOLECULAR & CELLULAR PROTEOMICS, 2005年10月, 査読有り
  • The therapeutic potential of tumor necrosis factor for autoimmune disease: a mechanistically based hypothesis
    S Kodama; M Davis; DL Faustman
    CELLULAR AND MOLECULAR LIFE SCIENCES, 2005年08月
  • Regenerative medicine: a radical reappraisal of the spleen
    S Kodama; M Davis; DL Faustman
    TRENDS IN MOLECULAR MEDICINE, 2005年06月, 査読有り
  • Vascular endothelial growth factor-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis.
    Hirakawa S; Kodama S; Kunstfeld R; Brown L; Detmar M
    J Exp Med, 2005年, 査読有り
  • Diabetes and stem cell researchers turn to the lowly spleen.
    Kodama S; Davis M; Faustman DL
    Science Online; SAGE KE, 2005年, 査読有り
  • Human pancreatic islet-derived Nestin positive progenitor cell engraftment immunocompetent mice.
    Abraham EJ; Kodama S; Lin JC; Ubera M; Smith N; Faustman DL; Habener JF
    Am J Pathol, 2004年, 査読有り
  • Routes to regeneration islet cells: stem cells and other biological therapies for type-1 diabetes.
    Kodama S; Faustman DL
    Pediatr Diabetes, 2004年
  • Islet regeneration during the reversal of autoimmune diabetes in NOD mice
    S Kodama; W Kuhtreiber; S Fujimura; EA Dale; DL Faustman
    SCIENCE, 2003年11月, 査読有り
  • Reversal of established autoimmune diabetes by restoration of endogenous beta cell function
    S Ryu; S Kodama; K Ryu; DA Schoenfeld; DL Faustman
    JOURNAL OF CLINICAL INVESTIGATION, 2001年07月, 査読有り
  • Prognostic significance of entrapped liver cells in hepatic metastases from colorectal cancer
    M Koike; K Yasui; A Torii; S Kodama
    ANNALS OF SURGERY, 2000年11月, 査読有り
  • Prolongation of rat islet xenograft survival in the liver of IFN-gamma-deficient mice
    T Maki; Y Yasunami; Y Ikehara; S Kodama; M Nakano; T Nakayama; M Taniguchi; S Ikeda
    JOURNAL OF SURGICAL RESEARCH, 2000年09月, 査読有り
  • CD4+ V alpha 14 natural killer T cells are essential for acceptance of rat islet xenografts in mice
    Y Ikehara; Y Yasunami; S Kodama; T Maki; M Nakano; T Nakayama; M Taniguchi; S Ikeda
    JOURNAL OF CLINICAL INVESTIGATION, 2000年06月, 査読有り
  • Hepatocyte growth factor is essential for amelioration of hyperglycemia in streptozotocin-induced diabetic mice receiving a marginal mass of intrahepatic islet grafts
    M Nakano; Y Yasunami; T Maki; S Kodama; Y Ikehara; T Nakamura; M Tanaka; S Ikeda
    TRANSPLANTATION, 2000年01月, 査読有り
  • LMP2 expression and proteasome activity in NOD mice.
    Hayashi T; Kodama S; Faustman DL; H.T; K.S. contributed equally to this wor
    Nat Med, 2000年, 査読有り
  • Expansion of CD8aa cells in the liver in association with autoimmune rejection of intrahepatic islet isografts in NOD mice.
    Kodama S; Yasunami Y; Maki T; Ikehara Y; Nakano N; Anzai K; Ono J; Ikeda S
    Transplantation, 1999年, 査読有り
  • Acceptance of intrahepatic islet allografts without immunosuppression in the limited strain combination of mice from C57BL/6 to BALB/c.
    Nagai T; Yasunami Y; Ikehara Y; Kodama S; Maki T; Ikeda S
    Transplant Proc, 1998年, 査読有り
  • Cellular immune response in the liver of mice rejecting intrahepatic rat and guinea pig islet xenografts: expansion of intermediate TCR cells.
    Yasunami Y; Maki T; Nagai T; Ikehara Y; Kodama S; Ikeda S
    Transplant Proc, 1998年, 査読有り
  • Expansion of intermediate T cell receptor cells expressing interleukin-2 receptor alpha-beta+, CD8alpha+beta+, and lymphocyte function-associated antigen-1+ in the liver in association with intrahepatic islet xenograft rejection from rat to mouse
    Otsuka K; Yasunami Y; Ikehara Y; Nagai T; Kodama S; Maki T; Tomita A; Abo T; Ikeda S
    Transplantation, 1997年, 査読有り
  • Adult hepatoblastoma: case report and review of the literature.
    Harada T; Matsuo K; Kodama S; Higasihara H; Nakayama Y; Ikeda S
    Aust N Z J Surg, 1995年
  • SURGICAL-MANAGEMENT OF LARGE HEPATOCELLULAR CARCINOMAS - CRITERIA FOR CURATIVE HEPATECTOMY
    T HARADA; S KODAMA; K MATSUO; T HIGUCHI; T NAGAI; S IKEDA; M OKAZAKI
    INTERNATIONAL SURGERY, 1993年10月, 査読有り
  • CHEMOEMBOLIZATION FOR HEPATOCELLULAR-CARCINOMA VIA THE INFERIOR PANCREATICODUODENAL ARTERY IN PATIENTS WITH CELIAC ARTERY-STENOSIS
    M OKAZAKI; H HIGASHIHARA; H ONO; F KOGANEMARU; R FUJIMITSU; Y MIZUMA; T NAKAMURA; S SATO; S KIMURA; S KODAMA
    ACTA RADIOLOGICA, 1993年01月, 査読有り
  • HEPATIC RESECTION IS NOT ENOUGH FOR HEPATOCELLULAR-CARCINOMA - A FOLLOW-UP-STUDY OF 92 PATIENTS
    T HARADA; T SHIGEMURA; S KODAMA; T HIGUCHI; S IKEDA; M OKAZAKI
    JOURNAL OF CLINICAL GASTROENTEROLOGY, 1992年04月, 査読有り
■ 講演・口頭発表等
  • 細胞組織移植における移植部位としての白色脂肪組織の有効性
    坂田 直昭; 吉松軍平; 小玉 正太
    第122回日本外科学会定期学術集会, 2022年04月14日, 日本外科学会
  • 膵島移植の治療効果向上におけるアディポネクチン利用の意義
    坂田 直昭; 吉松軍平; 知念澄志; 川上 亮; 小玉 正太
    第21回日本再生医療学会総会, 2022年03月17日, 日本再生医療学会
  • 1型糖尿病治療における膵島移植の位置づけと重要性
    坂田 直昭; 吉松軍平; 小玉 正太
    第57回日本移植学会総会, 2021年09月20日, 日本移植学会
  • 大学院生教育と振り返り
    坂田 直昭; 吉松軍平; 小玉 正太
    第53回日本医学教育学会大会, 2021年07月30日, 日本医学教育学会
  • The protocol of fat-covered islet transplantation using epididymal white adipose tissue
    坂田 直昭; 吉松軍平; 小玉 正太
    Joint Meeting of APITA and JPITA 2021: The 2nd Congress of Asian Pancreas and Islet Transplant Association, 2021年03月13日
  • 脂肪被覆膵島移植とその手法
    坂田 直昭; 吉松軍平; 小玉 正太
    第20回日本再生医療学会総会, 2021年03月11日
  • 臨床異種膵島移植実現のためのマイクロミニブタを使用した膵島単離と回収膵島の機能評価
    坂田 直昭; 吉松 軍平; 知念 澄志; 川上 亮; 小玉 正太
    第23回日本異種移植研究会, 2021年02月20日
  • 研究室紹介:福岡大学 再生・移植医学講座
    小玉 正太; 坂田 直昭; 吉松軍平
    第23回日本異種移植研究会, 2021年02月20日
  • 消化器病医における大学院教育の重要性
    坂田 直昭; 吉松 軍平; 小玉 正太
    第115回日本消化器病学会九州支部例会, 2020年06月19日
  • The Mechanism How the Transplanted Islets Engraft Into White Adipose Tissue
    Naoaki Sakata; Gumpei Yoshimatsu; Tomoko Tanaka; Ryo Kawakami; Shohta Kodama
    ATC 2020, 2020年05月31日, American Transplant Congress
  • 膵島異種移植における移植部位としての脂肪組織の可能性を考察する
    坂田 直昭; 吉松 軍平; 小玉 正太
    第22回日本異種移植研究会, 2020年02月15日, 日本異種移植研究会
  • 組織移植における移植部位としての白色脂肪組織の意義
    坂田 直昭; 吉松 軍平; 田中 智子; 川上 亮; 小玉 正太
    第55回日本移植学会総会, 2019年10月11日, 日本移植学会
  • 膵島移植における移植環境としての脂肪組織の特性
    坂田 直昭; 吉松 軍平; 田中 智子; 小玉 正太
    第18回日本組織移植学会総会・学術集会, 2019年08月03日, 日本組織移植学会
  • 慢性膵炎の外科手術:膵全摘術における自家膵島移植と膵臓移植
    坂田 直昭; 吉松 軍平; 小玉 正太
    第50回日本膵臓学会大会, 2019年07月12日, 日本膵臓学会
  • A novel type of intraperitoneal islet transplantation named “rolling-up method using epididymal adipose tissue”.
    坂田 直昭; 吉松 軍平; 小玉 正太
    17th World Congress of the INTERNATIONAL PANCREAS & ISLET TRANSPLANT ASSOCIATION, 2019年07月04日, The international pancreas & islet transplant association
  • The impact of islet purity on metabolic outcome after islet transplantation via portal vein
    YOSHIMATSU GUMPEI; GONOKAMI K; YAMADA TEPPEI; SAKATA Naoaki; KODAMA SHOHTA
    17th World Congress of the INTERNATIONAL PANCREAS & ISLET TRANSPLANT ASSOCIATION, 2019年07月03日, the INTERNATIONAL PANCREAS & ISLET TRANSPLANT ASSOCIATION
  • 移植膵島を同定するための画像検査について
    坂田 直昭; 吉松 軍平; 小玉 正太
    第18回日本再生医療学会総会, 2019年03月21日, 日本再生医療学会
  • 慢性膵炎に対する膵全摘術+自家膵島移植に関する提言
    坂田 直昭; 吉松 軍平; 小玉 正太
    第46回日本膵・膵島移植研究会, 2019年03月08日, 日本膵・膵島移植研究会
  • 精巣上体周囲脂肪組織被覆膵島移植より腹腔内膵島移植の概念を考える
    坂田 直昭; 吉松 軍平; 小玉 正太
    第46回日本膵・膵島移植研究会, 2019年03月08日, 日本膵・膵島移植研究会
  • IP-10をターゲットとした門脈内膵島移植における自然免疫反応の制御
    吉松 軍平; 山田 哲平; 坂田 直昭; Michael C. Lawrence; Bashoo Naziruddin; 海野 倫明; 小玉 正太
    第46回日本膵・膵島移植研究会, 2019年03月08日, 日本膵・膵島移植研究会
  • Intraperitoneal Islet Transplantation by Rolling-up Method Using Epididymal Adipose Tissue.
    坂田 直昭; 吉松 軍平; 小玉 正太
    The 1st Congress of APITA (Asian Pancreas and Islet Transplant Association), 2019年02月22日, Asian Pancreas and Islet Transplant Association
  • Cooperation among the donor coordinators, islet transplant facilities, and transplant associations for pancreas or islet is necessary to promote the islet transplantation.
    江崎 綾奈; 井山 なおみ; 吉松 軍平; 坂田 直昭; 小玉 正太
    The 1st Congress of APITA (Asian Pancreas and Islet Transplant Association), 2019年02月22日, Asian Pancreas and Islet Transplant Association
  • The impact of islet purity on metabolic outcome after islet transplantation into portal vein.
    吉松 軍平; 山田 哲平; 坂田 直昭; 小玉 正太
    The 1st Congress of APITA (Asian Pancreas and Islet Transplant Association), 2019年02月22日, Asian Pancreas and Islet Transplant Association
  • 異種膵島移植の今後の展望について
    小玉 正太; 坂田 直昭; 吉松 軍平; 高橋 宏幸; 松岡 泰祐; 山田 英明
    第54回日本移植学会総会, 2018年10月04日, 日本移植学会
  • Vascular endothelial growth factor-C derived from CD11b positive macrophages induces therapeutic improvements in a murine model of hind limb ischemia.
    Kuwahara G; Nishinakamura H; Kojima D; Tashiro T; Kodama S
    The 2012 Vascular Annual Meeting presented by Society for Vascular Surgery, 2012年06月07日
  • Two-layered tissue-engineered urethra using oral epithelial and muscle-derived cells.
    Mikami H; Kuwahara G; Nakamura N; Yamato M; Tanaka M; Kodama S
    Tissue Engineering & Regenerative Medicine International Society(TERMIS) –EU, 2011年07月07日
  • Islet regeneration -The possible inductions from adult-
    Shohta Kodama
    The Fourth International Conference on Cell Therapy, 2010年11月11日
  • A novel approach to prevent early loss of transplanted islets by targeting donor islets with a PPARγ agonist prior to transplantation.
    Mera T; Kojima D; Itoh T; Matsuoka N; Ono J; Kodama S; Yasunami Y
    XXIII International Congress of the Transplantation Society, 2010年08月15日
  • Early loss of transplanted islets in the liver of mice triggered by HMGB1 is prevented by antithrombin III.
    Kojima D; Mera T; Itoh T; Matsuoka N; Kodama S; YasunamiY
    XXIII International Congress of the Transplantation Society, 2010年08月15日
  • A candidate for organ specific stem cells that restricted cell diameter 2 to 5 µm in adult pancreas in non-obese diabetic mice.
    Kodama S; Kojima K; Paz AC; Chambers MA; Vacanti CA; Corresponding
    Tissue Engineering & Regenerative Medicine International Society(TERMIS), 2008年12月07日
  • Viability of Tissue-Enginneered Pancreatic Islet Cells Within A Tissue-Engineered Chondrocyte Matrix.
    Galvagno S; Furuta S; Kodama S; Kojima K; Vacanti CA; Corresponding
    Tissue Engineering & Regenerative Medicine International Society(TERMIS), 2008年12月07日
  • Engineering functional islets from cultured cells.
    Kodama S; Kojima K; uruta S; Paz AC; Vacanti CA; Corresponding
    Tissue Engineering & Regenerative Medicine International Society(TERMIS), 2008年12月07日
  • A candidate for organ specific stem cells that restricted cell diameter 2 to 5 µm in adult pancreas in non-obese diabetic mice.
    Kodama S; Kojima K; Paz AC; Chambers MA; Vacanti CA; Corresponding
    Tissue Engineering & Regenerative Medicine International Society(TERMIS), 2008年12月07日
  • Subclinical doses of Lidocaine and Bupivacaine inhibit bovine chondrocytes growth.
    Galvagno SM; Sukumar D; Kojima K; Paz AC; Vacanti C; Kodama S; Corresponding
    Massachusetts Medical Society Third Annual Research Poster Symposium, 2008年04月26日
  • Endothelial-specific Deletion of Inhibitor of Kappa-B Kinase-ß(IKK-ß).
    Ashida N; SenBanerjee S; Kodama S; Spencer J; Zamiri P; Gerszten RE; Lin C; Karin M; Rosenzweig A
    American Heart Association Scientific Sessions 2007, 2007年11月04日
  • Tissue Engineered Three-layered Artery Using Hemodynamically-equivalent Pulsatile Bioreactor.
    Iwasaki K; Kojima K; Kodama S; Paz AC; Chamber M; Umezu M; Vacanti CA
    American Heart Association Scientific Sessions 2007, 2007年11月04日
  • Endothelial-specific Deletion of Inhibitor of Kappa-B Kinase-ß(IKK-ß).
    Ashida N; SenBanerjee S; Kodama S; Spencer J; Zamiri P; Gerszten RE; Lin C; Karin M; Rosenzweig A
    American Heart Association Scientific Sessions 2007, 2007年11月04日
  • Lidocaine inhibits NIH-3T3 cell multiplication by increasing expression of cyclin- dependent kinase inhibitor 1A (p21).
    Sukumar D; Kojima K; Vacanti C; Kodama S; Corresponding
    Harvard Anesthesia Poster Evening, Harvard Medical School presented, 2007年10月30日
  • Treatment success and mechanisms of action influenced b age of NOD mice and target organ of autoimmune attack.
    Tran S; Kodama S; Mezey E
    The 66th Scientific Sessions of American Diabetes Association, 2006年06月09日
  • Biomarker development of autoreactive human and murine lymphocytes through altered apoptosis in Type 1 diabetes.
    Kutreiber WM; Kodama S; Burger DM; Faustman DL
    The 66th Scientific Sessions of American Diabetes Association, 2006年06月09日
  • Size restricted progenitor cells in the pancreas.
    Shohta Kodama
    BWH research lecture; Stem cell, regenerative medicine, and tissue engineering presented., 2006年05月17日
  • Hemodynamically-equivalent long-term pulsatile culturing system with carbon dioxide and oxygen supplementation for tissue engineering functional artery: From fetal circulation to adult circulation.
    Iwasaki K; Kojima K; Kodama S; Paz AC; Umezu M; Vacanti CA
    2005 Harvard review course: Current progress in tissue engineering and regenerative medicine presented, 2005年09月29日
  • VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis.
    Hirakawa S; Kodama S; Kunstfeld R; Brown L; Detmar M
    The 64th annual meeting of American Academy of Dermatology, 2005年05月04日
  • Adult stem cells initiate pancreatic regeneration.
    Fukuoka University, School of Medicine presented., 2004年10月02日
  • Islet regeneration during the reversal of autoimmune diabetes in NOD mice.
    Kodama S; Kuhtreiber W; Fujimura S; Dale E; Fautman DL
    The 12th international congress of immunology, 2004年07月18日
  • Islet regeneration during the reversal of autoimmune diabetes in NOD mice.
    Shohta Kodama
    Gene Therapy and Therapeutics Branch, NIH/NIDCR presented., 2004年05月24日
  • Defective Immunoproteosome(LMP2) Promotes Initial hyperplasia After Arterial Injury.
    Nishikawa K; Kolodgie F; Yasuda T; Kodama S; Virmani R; Finn A; Faustman D; Gold H
    The 4th annual conference on arteriosclerosis, thrombosis and vascular biology, 2003年05月08日
  • CD8aa T cells in the liver expand in association with autoimmune rejection of intrahepatic islet isografts in NOD mice.
    Kodama S; Yasunami Y; Maki T; Ikehara Y; Nakano N; Anzai K; Ono J; Ikeda S
    The 7th congress of the International Pancreas and Islet Transplant Association, 1999年08月22日
  • Expansion of CD8aa cells in the liver in association with autoimmune rejection of intrahepatic islet isografts in NOD mice.
    Kodama S; Yasunami Y; Maki T; Ikehara Y; Nakano N; Anzai K; Ono J; Ikeda S
    The 25th annual scientific meeting of the American Society of Transplant Surgeons, 1999年05月19日
  • Hepatocyte growth factor is essential for amelioration of hyperglycemia in streptozotocin-induced diabetic mice receiving a marginal mass of intrahepatic islet grafts.
    Nakano N; Yasunami Y; Maki T; Kodama S; Ikehara Y; Nakamura T; Tanaka M; Ikeda S
    The 25th annual scientific meeting of the American Society of Transplant Surgeons, 1999年05月19日
  • Prevemtion of immune rejection of intrahepatic islet xenografts from rat to mouse by anti-IL-2Rß monoclonal antibody treatment directed to intermediate TCR cells.
    Ikehara Y; Yasunami Y; Otsuka K; Nagai T; Kodama S; Maki T; Tomita A; Abo T; Ikeda S
    The 6th congress of the International Pancreas and Islet Transplant Association, 1997年09月24日
  • Prevemtion of immune rejection of intrahepatic islet xenografts from rat to mouse by anti-IL-2Rß monoclonal antibody treatment directed to intermediate TCR cells.
    Ikehara Y; Yasunami Y; Otsuka K; Nagai T; Kodama S; Maki T; Tomita A; Abo T; Ikeda S
    The 6th congress of the International Pancreas and Islet Transplant Association, 1997年09月24日
  • Extended systematicsubsegmentectomy of segment seven for hepatocellular carcinoma.
    Kakazu T; Inoue T; Ryu S; Kodama S; Ikeda S
    World Congress of CICD, 1996年09月13日
  • Rationale of surgical management for early gastric cancer.
    Kodama S; Yamamura Y; Kodera Y; Kito T
    1st International Gastric Cancer Congress, 1995年03月29日
  • The prognostic value of preoperative serum levels of CEA, CA19-9, AFP, and CA125 in patients with gastric cancer.
    Kodera Y; Yamamura Y; Kodama S; Kito T
    1st International Gastric Cancer Congress, 1995年03月29日
  • Surgical Management of Multiple Hepatocellular Carcinomas involving the Left and Right Lobes.
    Harada T; Matsuo K; Ikeda S; Kodama S; Shigemura T; Ikeda S
    Inaugural World Congress of the International Hepato-Pancreato Biliary Association, 1994年05月31日
  • Criteria for curative resection in hepatectomy for hepatocellular carcinoma larger than 5cm in diameter.
    Harada T; Kodama S; Matsuo K; Ikeda S
    The World Association of HPB Surgery 4th World congress, 1992年06月07日
■ 所属学協会
  • 日本移植学会
  • 日本組織移植学会
  • 日本膵・膵島移植研究会
  • 日本再生医療学会
  • 米国実験生物学会
  • 米国免疫学会
  • 国際膵・膵島移植学会
  • 国際移植学会
  • 国際組織工学・再生医学会
  • 米国移植外科学会
■ 産業財産権
  • 2012-553616, ・米国:13/993,832 ・欧州:12736365.3 ・台湾:101102154, 抗アポトーシス又は抗ネクロシース誘導方法
    小玉 正太, 五代 友行