SEARCH

Search Details
Last Updated :2024/04/12

okawa masafumi

Department of Phatmaceutics
Professor

Researcher information

■ Degree
  • 博士(薬学), 熊本大学大学院
  • Doctor, Kumamoto University
■ Research Keyword
  • Natural product antioxidants
■ Field Of Study
  • Life sciences, Pharmaceuticals - chemistry and drug development, Chemical Pharmaceutics

Career

■ Career
  • 2020
    福岡大学薬学部教授
  • 2007 - 2008
    福岡大学薬学部講師
  • 2008
    福岡大学薬学部准教授
  • 2004 - 2007
    福岡大学薬学部助手
  • 2001 - 2004
    Kumamoto University, Research Associate
■ Educational Background
  • Apr. 1997 - Mar. 1999
    Kumamoto University, Graduate School, Division of Pharmaceutical Sciences, Natural Medicines
  • Apr. 1993 - Mar. 1997
    Kumamoto University, Faculty of Pharmaceutical Science, 薬科学科

Research activity information

■ Paper
  • Two New Triterpene Glycosides in the Roots of Uraria crinita
    KINJO Junei; OKAWA Masafumi
    Chem Pharm Bull, Feb. 2019, Refereed
  • Seven new resin glycosides from the seeds of Quamoclit × multifida
    KINJO Junei; TSUCHIHASHI Ryota; OKAWA Masafumi
    J Nat Med, Jan. 2019, Refereed
  • A New Resin Glycoside, Muricatin IX, from the Seeds of Ipomoea muricata
    Masateru Ono; Saki Taketomi; Yuichi Kakiki; Shin Yasuda; Masafumi Okawa; Junei Kinjo; Hitoshi Yoshimitsu; Toshihiro Nohara
    CHEMICAL & PHARMACEUTICAL BULLETIN, Sep. 2016, Refereed
  • Two new triterpenoids from the seeds of blackberry (Rubus fructicosus)
    Masateru Ono; Shin Yasuda; Kaori Nishi; Kazutaka Yamamoto; Satoshi Fuchizaki; Satomi Higuchi; Haruki Komatsu; Masafumi Okawa; Junei Kinjo; Hitoshi Yoshimitsu; Toshihiro Nohara
    NATURAL PRODUCT RESEARCH, Apr. 2016, Refereed
  • Antiviral Activity of Four New Resin Glycosides Calysolins XIV–XVII from Calystegia soldanella against Herpes Simplex Virus
    OKAWA Masafumi; KINJO Junei
    Chem Pharm Bull, 01 Aug. 2015, Refereed
  • Screening of promising chemotherapeutic candidates from plants against human adult T-cell leukemia/lymphoma (IV): phenanthroindolizidine alkaloids from Tylophora tanakae leaves
    NAKANO Daisuke; TSUCHIHASHI Ryota; OKAWA Masafumi; KINJO Junei
    J Nat Med, 2015, Refereed
  • Analysis of Seasonal Variation in the Amounts of Phytochemicals in Kudzu (Pueraria lobata) Leaves Using HPLC with Evaporative Light Scattering Detection
    TSUCHIHASHI Ryota; NAKANO Daisuke; OKAWA Masafumi; KINJO Junei
    International Journal of Plant Biology and Research, 2015, Refereed
  • Four new acylated glycosidic acid methyl esters isolated from the convolvulin fraction of seeds of Quamoclit pennata after treatment with indium(III) chloride in methanol
    Ono M; Akiyama K; Yamamoto K; Mineno T; Okawa M; Kinjo J; Miyashita H; Yoshimitsu H; Nohara T
    Chem Pharm Bull, Aug. 2014, Refereed
  • Calysolins X-XIII, resin glycosides from Calystegia soldanella, and their antiviral activity toward herpes simplex virus
    Ono M; Kawakami G; Takigawa A; Kabata K; Okawa M; Kinjo J; Yokomizo K; Yoshimitsu H; Nohara T
    Chem Pharm Bull, Aug. 2014, Refereed
  • Calysolins V-IX, resin glycosides from Calystegia soldanella and their antiviral activity toward herpes
    KINJO Junei; OKAWA Masafumi
    Chem Pharm Bull, Jan. 2014, Refereed
  • Five new resin glycoside derivatives isolated from the convolvulin fraction of seeds of Quamoclit pennata after treatment with indium(III) chloride in methanol
    KINJO Junei; OKAWA Masafumi
    Chem Pharm Bull, Jan. 2014, Refereed
  • Screening of promising chemotherapeutic candidates from plants against human adult T-cell leukemia/lymphoma (III)
    KINJO Junei; NAKANO Daisuke; TSUCHIHASHI Ryota; OKAWA Masafumi
    J Nat Med, Sep. 2013
  • Three Acylated Glycosidic Acid Methyl Esters and Two Acylated Methyl Glycosides Generated from the Convolvulin Fraction of Seeds of Quamoclit pennata by Treatment with Indium(III) Chloride in Methanol
    KINJO Junei; OKAWA Masafumi
    J Nat Med, Sep. 2013, Refereed
  • Five new nortriterpenoid glycosides from the bulbs of Scilla scilloides
    KINJO Junei; OKAWA Masafumi
    Chem Pharm Bull., May 2013, Refereed
  • A new diterpenoid from the leaves of Clerodendron trichotomum
    KINJO Junei; OKAWA Masafumi
    J Nat Med., Feb. 2013, Refereed
  • Screening of chemotherapeutic candidates from plants against ATL (II): apoptosis of antiproliferactive principle (24,25-dihydrowithanolide D) and structure-activity relationships with withanolides isolated from solanaceous plants
    KINJO Junei; NAKANO Daisuke; OKAWA Masafumi; TSUCHIHASHI Ryota
    J Nat Med., Feb. 2013, Refereed
  • Two New Nortriterpenoid Glycosides and a New Phenylpropanoid Glycoside from the Bulbs of Scilla scilloides
    Ono M; Takatsu Y; Ochiai T; Yasuda S; Nishida Y; Tanaka T; Okawa M; Kinjo J; Yoshimitsu H; Nohara T
    Chem Pharm Bull., Oct. 2012, Refereed
  • Three New Resin Glycosides and a New Tetrahydropyran Derivative from the Seeds of Quamoclit pennata
    Ono M; Takaki Y; Takatsuji M; Akiyama K; OKAWA Masafumi; KINJO Junei; Miyashita H; Yoshimitsu H; Nohara T
    Chem Pharm Bull, Aug. 2012, Refereed
  • Calysolins I-IV, resin glycosides from Calystegia soldanella
    Takigawa A; Muto H; Kabata K; OKAWA Masafumi; KINJO Junei; Yoshimitsu H; Nohara T; Ono M
    J Nat Prod., Nov. 2011, Refereed
  • Oleanene Glycosides of the Aerial Parts and Seeds of Bupleurum falcatum and the Aerial Parts of Bupleurum rotundifolium, and their Evaluation of as Anti-hepatitis Agents
    Yuko NAKAHARA; OKAWA Masafumi; KINJO Junei; Toshihiro NOHARA
    Chem. Pharm. Bull., Nov. 2011
  • Garlicnin A from the Fraction Regulating Macrophage Activation of Allium sativum
    Mona EL-AASR; Fujiwara Y; Takeya M; Masateru ONO; NAKANO Daisuke; OKAWA Masafumi; KINJO Junei; Tsuyoshi IKEDA; Hiroyuki MIYASHITA; TSUKAMOTO; Hitoshi YOSHIMITSU; Toshihiro NOHARA
    Chem. Pharm. Bull., Nov. 2011, Refereed
  • Three new nortriterpene glycosides and two new triterpene glycosides from the bulbs of Scilla scilloides
    Ono M; Toyohisa D; Morishita T; Horita H; Yasuda S; Nishida Y; Tanaka T; OKAWA Masafumi; KINJO Junei; Yoshimitsu H; Nohara T
    Chem Pharm Bull, Nov. 2011, Refereed
  • 大麦若葉から分離したルトナリンの抗酸化作用
    OKAWA Masafumi; KINJO Junei
    日本食品科学工学会誌, Sep. 2011, Refereed
  • Identification and Characterization of Component Organic and Glycosidic Acids of Crude Resin Glycoside Fraction from Calystegia soldanella
    Takigawa A; Setoguchi H; OKAWA Masafumi; KINJO Junei; Miyashita H; Yokomizo K; Yoshimitsu H; Nohara T; Ono M
    Chem Pharm Bull, Sep. 2011, Refereed
  • Four New Iridoid Glucosides from Ajuga reptans
    Ono M; Furusawa C; Ozono T; Oda K; Yasuda S; OKAWA Masafumi; KINJO Junei; Ikeda T; Miyashita H; Yoshimitsu H; Nohara T
    Chem Pharm Bull, Aug. 2011, Refereed
  • Screening of promising chemotherapeutic candidates against human adult T-cell leukemia/lymphoma from plants: active principles from Physalis pruinosa and structure-activity relationships with withanolides.
    NAKANO Daisuke; ISHITSUKA KENJI; TSUCHIHASHI Ryota; OKAWA Masafumi; TAMURA Kazuo; KINJO Junei
    J Nat Med., Jul. 2011, Refereed
  • A New Diterpenoid Glucoside and Two New Diterpenoids from the Fruit of Vitex agnus-castus
    Ono M; Eguchi K; Konoshita M; Furusawa C; Sakamoto J; Yasuda S; Ikeda T; OKAWA Masafumi; KINJO Junei; Yoshimitsu H; Nohara T
    Chem Pharm Bull, Mar. 2011, Refereed
  • Components of convolvulin from Quamoclit × multifida
    Ono M; Kishida M; Ikegami Y; Takaki Y; OKAWA Masafumi; KINJO Junei; Yoshimitsu H; Nohara T; Miyahara K
    J Nat Med., Feb. 2011, Refereed
  • Onionin A from Allium cepa inhibits macrophage activation
    El-Aasr M; Fujiwara Y; Takeya M; Ikeda T; Tsukamoto S; Ono M; Nakano D; Okawa M; Kinjo J; Yoshimitsu H; Nohara T
    Journal of Natural Products, Jul. 2010, Refereed
  • Three New aromatic glycosides from the ripe fruit of cherry tomato
    Ono M; Shiono Y; Tanaka T; Masuoka C; Yasuda S; Ikeda T; Okawa M; Kinjo J; Yoshimitsu H; Nohara T
    Journal of Natural Medicines, Jun. 2010, Refereed
  • Three new diterpenoids from the fruit of Vitex agnus-castus
    Ono M; Nagasawa Y; Ikeda T; Tsuchihashi R; Okawa M; Kinjo J; Yoshimitsu H; Nohara T
    Chem Pharm Bull, Oct. 2009
  • Two New Acyclic Diterpene Glycosides from Fruits of Habanero, Capsicum chinense.
    Lee JH; El-Aasr M; Ikeda T; Oda K; Miyashita H; Yoshimitsu H; Okawa M; Kinjo J; Nohara T
    Chem Pharm Bull, Jul. 2009, Refereed
  • Five New Steroidal Glycosides from the Stems of Solanum sodomaeum
    Ono M; Uenosono Y; Umaoka H; Shiono Y; Ikeda T; Okawa M; Kinjo J; Yoshimitsu H; Nohara T
    Chem Pharm Bull, Jul. 2009, Refereed
  • A New Lignan Glucoside from the stems of Callicarpa japonica Thunb. var. luxurians Rehd.
    Masateru Ono; Kenji Mishima; Toru Yamasaki; Chikako Matsuoka; Masafumi Okawa; Junei Kinjo; Tsuyoshi Ikeda; Toshihiro Nohara
    Journal of Natural Medicines, Feb. 2009, Refereed
  • Five New Diterpenoids, Viteagnusins A - E, from the Fruits of Vitex agnus-castus
    Masateru Ono; Toru Yamasaki; Masatarou Konoshita; Tsuyoshi Ikeda; Masafumi Okawa; Junei Kinjo; Hitoshi Yoshimitsu; Toshihiro Nohara
    Chem. Pharm. Bull., Nov. 2008, Refereed
  • Studies on the Constituents of Gueldenstaedtia multiflora
    Yuki Tsunoda; Masafumi Okawa; Junei Kinjo; Tsuyoshi Ikeda; Toshihiro Nohara
    Chem. Pharm. Bull., Aug. 2008, Refereed
  • Three New Monoterpenoids from the Fruit of Genipa americana
    M.Ono; N. Ishimatsu; C. Masuoka; H. Yoshimitsu; R. Tsuchihashi; M. Okawa; J. Kinjo; T. Ikeda; T. Nohara
    Chem. Pharm. Bull., Apr. 2007, Refereed
  • Bisabolane-Type Sesquiterpenes from the Aerial Parts of Lippia dulcis
    M.Ono; T. Tsuru; H. Abe; M. Eto; M. Okawa; F. Abe; J. Kinjo; T. Ikeda; T. Nohara
    Journal of Natural Products, Oct. 2006, Refereed
  • 植物中の抗トリパノソーマ活性成分についてー6 センナリホオズキ地上部のウィタノライドについて
    ABE Fumiko; KINJO Junei; OKAWA Masafumi
    Chem. Pharm. Bull., Aug. 2006, Refereed
  • Hepatoprotective Constituents in Plants 15. Protective Effects of Natural-Occurring Flavonoids and Miscellaneous Phenolic Compounds on an HepG2 Cell Cytotoxicity Assay
    J. Kinjo; M. Hitoshi; R. Tsuchihashi; Y. Korematsu; M. Miyakoshi; T. Murakami; D. Araho; K. Mizutani; T. Tanaka; G. Nonaka; T. Nohara; M. Okawa; H. Okabe
    Journal of Natural Medicines, Jan. 2006, Refereed
  • Pregnane- and Furostane-Type Oligoglycosides from the Seeds of Allium tuberosum. (共著)
    Chem. Pharm. Bull., 2004
  • Pregnane- and Furostane-Type Oligoglycosides from the Seeds of Allium tuberosum. (共著)
    Chem. Pharm. Bull., 2004
  • HPLC Profile Analysis of Hepatoprotective Oleanene-Glucuronides in Several Soybean Processed Foods
    TSUCHIHASHI Ryota; KINJO Junei
    Natural Medicines, Dec. 2003, Refereed
  • Steroids from the underground parts of Trillium kamtschaticum
    M Ono; Y Yanai; T Ikeda; M Okawa; T Nohara
    CHEMICAL & PHARMACEUTICAL BULLETIN, Nov. 2003
  • Two new 15,16-seco-cycloartane glycosides from Cimicifuga Rhizome
    M Nishida; H Yoshimitsu; M Okawa; T Ikeda; T Nohara
    CHEMICAL & PHARMACEUTICAL BULLETIN, Oct. 2003
  • Hepatoprotective Constituents in Plants 14. Effects of Soyasapogenol B, Sophoradiol, and Their Glucuronides on the Cytotoxicity of tert-Butyl Hydroperoxide to HepG2 Cells
    KINJO Junei; TSUCHIHASHI Ryota; OKAWA Masafumi
    Biol. Pharm. Bull., Sep. 2003, Refereed
  • Antiproliferative Activity of Phenylpropanoid Ester Glycosides from Ligustrum purpurascens
    OKAWA Masafumi; KINJO Junei
    Natural Medicines, Oct. 2002, Refereed
  • Activity-guided fractionation of green tea extract with antiproliferative activity against human stomach cancer cells
    J Kinjo; T Nagao; T Tanaka; G Nonaka; M Okawa; T Nohara; H Okabe
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, Sep. 2002, Refereed
  • Five triterpene glycosides from Oxytropis myriophylla
    M Okawa; R Yamaguchi; H Delger; R Tsuchihashi; T Nohara; J Kinjo; S Isoda; Y Ida
    CHEMICAL & PHARMACEUTICAL BULLETIN, Aug. 2002, Refereed
■ Books and other publications
  • 医療を指向する天然医薬品化学
    大川雅史; 大塚功; 片川和明; 川口基一郎; 北中進; 高松智; 平井康明; 平野裕之; 船山信次; 安田高明, Joint editor, pp221-pp260
    Hirokawa Pablishing Co., Mar. 2011
    9784567431118
■ Lectures, oral presentations, etc.
  • Trypanocidal Constituents Obtainded from Aerial Parts of Physalis philadelphica
    OKAWA Masafumi; ABE Fumiko; KINJO Junei
    2006' International Symposium for Pharmaceutical in Beijing, 11 Oct. 2006
  • Soy Isoflavone Metabolites from Human Urine
    TSUCHIHASHI Ryota; OKAWA Masafumi; KINJO Junei
    2006' International Symposium for Pharmaceutical in Beijing, 11 Oct. 2006
■ Affiliated academic society
  • The Japanese Environmental Mutagen Society
  • The Japanese Society of Pharmacognogy
  • 日本薬学会
■ Social Contribution Activities
  • 自然と薬草に親しむ集い
    lecturer
    佐賀県薬務課, 北山ダム周辺, 06 Oct. 2018
  • 自然と薬草に親しむ会
    lecturer
    佐賀県薬務課, 北山ダム周辺, 06 Oct. 2018
  • 皿倉山薬用植物観察会
    lecturer
    (公)八幡東薬剤師会, 皿倉山山頂周辺, 20 Oct. 2013