SEARCH
Search Details
Last Updated :2025/04/25
Hirotomo Shibaguchi
School of Medicine
Lecturer/Senior Assistant Professor
Profile2011- Development of high-sensitive allergy test analyzing the cell kinetics 2006- Development of non-invasive sonodynamic cancer therapy using low-intensity ultrasound together with sonosensitizer 2002- Immunotherapy and gene therapy for cancer with monoclonal and scFv antibodies specific for carcinoembryonic antigen (CEA) 1996-2001 Mechanisms for Neurological Disorder 1992-1996 Role of Endothelin in Neuroral Dea
Researcher information
■ Degree
- 博士（医学）, 長崎大学
- 修士（薬学）, 長崎大学
- Master(Pharmaceutical Science), Nagasaki University
- Doctor(Medicine), Nagasaki University
- diagnosis of allergy
- genes of hAbs
- human antibodies (hAbs)
- gene therapy
- immunotherapy
- sonodynamic therapy
- Cancer
- Other, Other, Medicine, dentistry, and pharmacy Laboratory medicine Methods for predincting drug-induced allergy
- Life sciences, Biomaterials, Cancer sonodynamic therapy with low-intensity ultrasound
- Life sciences, Biomedical engineering, Cancer sonodynamic therapy with low-intensity ultrasound
- Other, Other, Methods for predincting drug-induced allergy Laboratory medicine
Career
■ Career
- 2001 - 2009
Research assistant Fukuoka University School of Medicine - 2009
Senior Assistant Professor - 2000 - 2001
Mayo Clinic Jacksonville, Research Fellow - 1998 - 2000
INSERM, Postdoctoral Fellow - 1997 - 2000
Nagasaki University School of Medicine, Research Associate - 1996 - 1997
Nagasaki University School of Medicine, Instructor
Research activity information
■ Paper
- Highly versatile cancer photoimmunotherapy using photosensitizer-conjugated avidin and biotin-conjugated targeting antibodies.
SHIRASU Naoto; SHIBAGUCHI Hirotomo; YAMADA Hiromi; KUROKI Masahide; YASUNAGA Shin'ichiro
Cancer Cell Int., 15 Nov. 2019, 19:299, Refereed - Enhancement of antitumor activity by using a fully human gene encoding a single-chain fragmented antibody specific for carcinoembryonic antigen
Hirotomo Shibaguchi; Naixiang Luo; Naoto Shirasu; Motomu Kuroki; Masahide Kuroki
ONCOTARGETS AND THERAPY, 2017, 10:3979 - 3990, Refereed - パーキンソン病治療薬ロチゴチン貼付剤の継続使用に関する検討
安高勇気; 藤岡伸助; 芝口浩智; 今給黎 修; 鷲山厚司; 坪井義夫; 二神幸次郎
BRAIN and NERVE, 01 Jun. 2016, 68(6):655 - 660, Refereed - 薬剤アレルギー同定の効率化に関する基礎的検討 ―1次スクリーニングとしての細胞動態解析―
安高勇気; 芝口浩智; 黒木政秀; 松永 彰; 二神幸次郎
医療薬学, Jan. 2015, 41(1):11 - 17, Refereed - Potent and specific antitumor effect of CEA-targeted photoimmunotherapy
Naoto Shirasu; Hiromi Yamada; Hirotomo Shibaguchi; Motomu Kuroki; Masahide Kuroki
INTERNATIONAL JOURNAL OF CANCER, Dec. 2014, 135(11):2697 - 2710, Refereed - 病院実務実習におけるポートフォリオの評価
安高勇気; 中島章雄; 芝口浩智; 鷲山厚司; 二神幸次郎
医療薬学, Mar. 2014, 40(3):154 - 159, Refereed - ヒト抗CEA抗体を用いた腫瘍選択的な近赤外光免疫療法の検討．
白須直人; 山田博美; 芝口浩智; 黒木 求; 黒木政秀
日本分子腫瘍マーカー研究会誌, 2013, 28(1):27 - 28, Refereed - Tumor growth inhibition by sonodynamic therapy using a novel sonosensitizer
Hirofumi Tsuru; Hirotomo Shibaguchi; Motomu Kuroki; Yuichi Yamashita; Masahide Kuroki
FREE RADICAL BIOLOGY AND MEDICINE, Aug. 2012, 53(3):464 - 472, Refereed - Molecular Characterization of a fully human chimeric T cell antigen receptor for tumor-associated antigen EpCAM.
Shirasu N; Yamada H; Shibaguchi H; Kuroki M; Kuroki M
J Biomed Biotech, 2012, :2012:853879, Refereed - 副作用報告に関する実務実習教育プログラム
山本知佳; 上野雅代; 植山美穂; 岡村亜紗美; 鷲山厚司; 芝口浩智; 二神幸次郎
薬学雑誌, 2012, 132(6):769 - 775 - Enhancement of the Antitumor Effect on Combination Therapy of an Anticancer Drug and Its Antibody against Carcinoembryonic Antigen
Hirotomo Shibaguchi; Hirofumi Tsuru; Motomu Kuroki; Masahide Kuroki
CHEMOTHERAPY, 2012, 58(2):110 - 117, Refereed - Sonodynamic therapy with 5-aminolevulinic acid and focused ultrasound for deep-seated intracranial glioma in rat.
Ohmura T; Fukushima K; Shibaguchi H; Yoshizawa S; Inoue T; Kuroki M; Sasaki K; Umemura SI
Anticancer Research, 2011, 31(7):2527 - 2534 - Sonodynamic cancer therapy: a non-invasive and repeatable approach using low-intensity ultrasound with a sonosensitizer
Shibaguchi H; Tsuru H; Kuroki M; Kuroki M
Anticancer Research, 2011, 31:2425 - 2430, Refereed - Construction and Molecular Characterization of Human Chimeric T-Cell Antigen Receptors Specific for Carcinoembryonic Antigen
Naoto Shirasu; Hirotomo Shibaguci; Motomu Kuroki; Hiromi Yamada; Masahide Kuroki
ANTICANCER RESEARCH, Jul. 2010, 30(7):2731 - 2738 - 新人薬剤師による薬学部1年生早期体験学習実施体制の構築
山本知佳; 鷲山厚司; 勢島英; 芝口浩智; 片岡泰文; 二神幸次郎
薬学雑誌, 2010, 130(6):8211 - 831 - ヒト免疫グロブリン製剤における抗サイトメガロウイルス抗体の力価測定とその評価
芝口浩智; 山本知佳; 黒木政秀; 二神幸次郎
薬学雑誌, 2010, 130(7):977 - 982, Refereed - PPAR alpha Ligand WY14643 Reduced Acute Rejection After Rat Lung Transplantation With The Upregulation of IL-4, IL-10 and TGF beta mRNA Expression
Jun Yanagisawa; Takeshi Shiraishi; Akinori Iwasaki; Shinichi Maekawa; Takao Higuchi; Masafumi Hiratuka; Toshihiro Tanaka; Hirotomo Shibaguchi; Masahide Kuroki; Takayuki Shirakusa
JOURNAL OF HEART AND LUNG TRANSPLANTATION, Nov. 2009, 28(11):1172 - 1179, Refereed - Claudin-1 Protein is a Major Factor Involved in the Tumorigenesis of Colorectal Cancer
Qun Huo; Tetsushi Kinugasa; Lin Wang; Jian Huang; Jun Zhao; Hirotomo Shibaguchi; Motomu Kuroki; Toshihiro Tanaka; Yuichi Yamashita; Kazuki Nabeshima; Hiroshi Iwasaki; Masahide Kuroki
ANTICANCER RESEARCH, Mar. 2009, 29(3):851 - 857, Refereed - Association between the expression of chemokine receptors CCR7 and CXCR3, and lymph node metastatic potential in lung adenocarcinoma
Shinichi Maekawa; Akinori Iwasaki; Takayuki Shirakusa; Takehito Kawakami; Jun Yanagisawa; Toshihiro Tanaka; Hirotomo Shibaguchi; Testushi Kinugasa; Motomu Kuroki; Masahide Kuroki
ONCOLOGY REPORTS, Jun. 2008, 19(6):1461 - 1468, Refereed - Recombinant Human Monoclonal IgA Antibody Against CEA to Recruit Neutrophils to CEA-Expressing Cells
Jun Zhao; Motomu Kuroki; Hirotomo Shibaguchi; Lin Wang; Qun Huo; Noboru Takami; Toshihiro Tanaka; Tetsushi Kinugasa; Masahide Kuroki
ONCOLOGY RESEARCH, 2008, 17(5):217 - 222, Refereed - Sonodynamic therapy of cancer using novel sonosensitizers
Masahide Kuroki; Ken Hachimine; Hironori Abe; Hirotomo Shibaguchi; Motomu Kuroki; Shin-ichi Maekawa; Jun Yanagisawa; Tetsushi Kinugasa; Toshihiro Tanaka; Yuichi Yamashita
ANTICANCER RESEARCH, Nov. 2007, 27(6A):3673 - 3677, Refereed - Cancer-targeting gene therapy using tropism-modified adenovirus
Toshihiro Tanaka; Motomu Kuroki; Hirofumi Hamada; Kazuncri Kato; Tetsushi Kinugasa; Hirotomo Shibaguchi; Jun Zhao; Masahide Kuroki
ANTICANCER RESEARCH, Nov. 2007, 27(6A):3679 - 3684, Refereed - Selective up-regulation of claudin-1 and claudin-2 in colorectal cancer
Tetsushi Kinugasa; Qun Huo; Daijiro Higash; Hirotomo Shibaguchi; Motomij Kuroki; Toshihiro Tanaka; Kitarou Futami; Yuichi Yamashita; Ken Hachimine; Shinichi Maekawa; Kazuki Nabeshima; Hiroshi Iwasaki; Masahide Kuroki
ANTICANCER RESEARCH, Nov. 2007, 27(6A):3729 - 3734, Refereed - Sonodynamic therapy of cancer using a novel porphyrin derivative, DCPH-P-Na(I), which is devoid of photosensitivity
Ken Hachimine; Hirotomo Shibaguchi; Motomu Kuroki; Hiromi Yamada; Tetsushi Kinugasa; Yoshinori Nakae; Ryuji Asano; Isao Sakata; Yuichi Yamashita; Takayuki Shirakusa; Masahide Kuroki
CANCER SCIENCE, Jun. 2007, 98(6):916 - 920, Refereed - Granulocyte and monocyte adsorption adheresis therapy for ulcerative colitis patients: a useful tool for surgical indication assessments.
Kinugasa T; Kuroki M; Toyohara T; Morita N; Kuromizu J; Ua; asjota Y; Shirakusa T; Shibaguchi H; Kuroki M
Med. Bull. Fukuoka Univ., Dec. 2006, 33(4):283 - 291, Refereed - Possible applications of antibodies or their genes in cancer therapy
Masahide Kuroki; Jian Huang; Hirotomo Shibaguchi; Toshihiro Tanaka; Jun Zhao; Naixiang Luo; Ken Hachimine; Tetsushi Kinugasa; Shin-Ichi Maekawa; Sotaro Enatsu; Wakako Hamanaka; Tatsuya Fukami; Motomu Kuroki
ANTICANCER RESEARCH, Nov. 2006, 26(6A):4019 - 4025, Refereed - A fully human chimeric immune receptor for retargeting T-cells to CEA-expressing tumor cells
Hirotomo Shibaguchi; Nai-Xiang Luo; Motomu Kuroki; Jun Zhao; Jian Huang; Ken Hachimine; Tetsushi Kinugasa; Masahide Kuroki
ANTICANCER RESEARCH, Nov. 2006, 26(6A):4067 - 4072, Refereed - Replacement of the constant region gene of a novel anti-CEA antibody and characterization of its biological activity.
Huang J; Shibaguchi H; Kuroki M
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi., Sep. 2006, 22(5):650 - 653 - キメラ受容体（CIR）を利用したがんの免疫療法ー抗腫瘍効果を中心にー
Shibaguchi H; Kuroki M; Kinugasa T; Tanaka T; Kuroki M
Med. Bull. Fukuoka Univ., Sep. 2006, 33(3):243 - 249, Refereed - 腫瘍細胞障害活性増強のための新規ヒト抗体IgGサブクラス変換
芝口浩智
Research, Sep. 2006, 11(3):15 - 16 - キメラ受容体（CIR）を利用したがんの免疫療法
Shibaguchi H; Kuroki M; Kinugasa T; Kuroki M
Med. Bull. Fukuoka Univ., Jun. 2006, 33(2):143 - 150, Refereed - IgG isotype conversion of a novel human anti-carcinoembryonic antigen antibody to increase its biological activity.
Huang J; Shibaguchi H; Zhao J; Luo N; Kuroki M; Kinugasa T; Hirose Y; Yamada H; Kuroki M
Anticancer Res., Apr. 2006, 26(2A):1057 - 1063 - Preparation of human IgG and IgM monoclonal antibodies for MK-1/Ep-CAM by using human immunoglobulin gene-transferred mouse and gene cloning of their variable regions.
Kuroki M; Yamada H; Shibaguchi H; Hachimine K; Hirose Y; Kinugasa T; Ishida I; Kuroki M
Anticancer Res., Dec. 2005, 25(6A):3733 - 3739, Refereed - Re-targeting of cytotoxic T lymphocytes and/or natural killer cells to CEA-expressing tumor cells with anti-CEA antibody activity.
Kuroki M; Hachimine K; Huang J; Shibaguchi H; Kinugasa T; Maekawa S; Kuroki M
Anticancer Res., Dec. 2005, 25(6A):3725 - 3732, Refereed - Prevention of acute lung allograft rejection in rat by the Janus kinase 3 inhibitor, tyrphostin AG490
T Higuchi; T Shiraishi; M Shirakusa; S Hirayama; H Shibaguchi; M Kuroki; M Hiratuka; S Yamamoto; A Iwasaki; M Kuroki
JOURNAL OF HEART AND LUNG TRANSPLANTATION, Oct. 2005, 24(10):1557 - 1564, Refereed - Purkinje-cell degeneration in prion protein-deficient mice is associated with a cerebellum-specific Doppel protein species signature
R Al Bersaoui; Robert, I; Y Lutz; F Blanc; G Sommermeyer-Leroux; H Shibaguchi; D Aunis; JP Fuchs
FEBS LETTERS, May 2005, 579(12):2715 - 2721, Refereed - タイトジャンクション（TJ）関連タンパク質の基礎と臨床
福岡大学医学紀要, 2005, 32(4):167 - 172 - Subclass conversion from IgG4 to IgG1 of a novel human anti-CEA antibody for increasing its biological activity
Mol. Tumor Maker Res., 2005 - 抗体を利用した癌治療法の現状と新展開
KUROKI Masahide; SHIBAGUCHI Hirotomo; KUROKI Motomu
日本補完代替医療学会誌, 2005, 2(1):15 - 21 - 胃癌患者血清中におけるCEACAM6値およびCEA値の比較検討
K. T.; K. M.; K. M.; S. H.; Y. Y.; S. T.
日本分子腫瘍マーカー研究会誌, 2005, 20(1):50 - 51 - 癌関連抗原MK-1に特異的なヒトモノクローナル抗体の作成
日本分子腫瘍マーカー研究会誌, 2005, 20(1):44 - 45 - CEAに特異的なヒト単鎖抗体scFv45とIL-2融合タンパク質の作成とその性状解析
日本分子腫瘍マーカー研究会誌, 2005, 20(1):46 - 47 - Cloning and sequencing of variable region cDNAs of a novel human monoclonal antibody to carcinoembryonic antigen, and generation of a single chain variable fragmented antibody.
Shibaguchi H; Kuroki M; Kuroki M; Badran A; Hachimine K; Kinugasa T
Anticancer Res., Oct. 2004, 24(5C):3355 - 3360., Refereed - Tumor-targeting of viral vectors for cancer gene therapy by using antibodies or their genes against tumor-associated antigens.
Kuroki M; Kuroki M; Shibaguchi H; Hachimine K; Kinugasa T; Badran A
Anticancer Res., Oct. 2004, 24(5C):3373 - 3377., Refereed - Strategies to Endow Cytotoxic T Lymphocytes or Natural Killer Cells with Antibody Activity against Carcinoembryonic Antigen.
Kuroki M; Kuroki M; Shibaguchi H; Badran A; Hachimine K; Zhang J; Kinugasa T
Tumour Biol., Aug. 2004, 25(4):208 - 216., Refereed - Generation, immunologic characterization and antitumor effects of human monoclonal antibodies for carcinoembryonic antigen.
Imakiire T; Kuroki M; Shibaguchi H; Abe H; Yamauchi Y; Ueno A; Hirose Y; Yamada H; Yamashita Y; Shirakusa T; Ishida I; Kuroki M
Int J Cancer, Feb. 2004, 108(4):564 - 570., Refereed - 癌の診断と治療における腫瘍関連抗原の新しい応用法
日気食会報, 2004, 55(2):55 - 64 - KMマウスによるヒト抗体作製－抗CEA抗体を中心として－
分子細胞治療, 2004, 3(4):41 - 47 - Immunotherapy and gene therapy of cancer using antibodies or their genes against tumor-associated antigens.
Kuroki M; Shibaguchi H; Imakiire T; Uno K; Shirota K; Higuchi T; Shitama T; Yamada H; Hirose Y; Nagata A; Kuroki M
Anticancer Res., Dec. 2003, 23(6A):4377 - 4381., Refereed - cDNA cloning and sequencing of a novel monoclonal antibody to carcinoembryonic antigen and construction of a mouse/human chimeric antibody.
Shibaguchi H; Arakawa F; Imakiire T; Kuroki M; Kuroki M
Anticancer Res., Dec. 2003, 23(6A):4383 - 4388., Refereed - 癌治療の標的としての分子腫瘍マーカー：17-1AとCEAを中心として
日本分子腫瘍マーカー研究会誌, 2003, :19(1):13 - 14 - がん特異的なキメラ受容体による免疫細胞の腫瘍標的化
Research, 2003, 8(4):16 - 17 - CEAに特異的なヒトモノクローナル抗体の可変領域の塩基配列決定と単鎖抗体作製
分子腫瘍マーカー研究会誌, 2003, 19(1):49 - 50 - Anti-tumor effect of an immunotoxin consisting of a chimeric anti-carcinoembryonic antigen antibody conjugated to ricin toxin A.
Med. Bull. Fukuoka Univ., 2003, 30(4):243 - 247, Refereed - Significance of tumor-associated antigens in the diagnosis and therapy of cancer: an overview.
Kuroki M; Ueno A; Matsumoto H; Abe H; Li T; Imakiire T; Yamauchi Y; Uno K; Shirota K; Shibaguchi H; Kuroki M
Anticancer Res., Dec. 2002, 22(6C):4255 - 4264., Refereed - Targeting of T cells to CEA-expressing tumor cells by chimeric immune receptors with a highly specific single-chain anti-CEA activity.
Arakawa F; Shibaguchi H; Xu Z; Kuroki M
Anticancer Res., Dec. 2002, 22(6C):4285 - 4389., Refereed - 癌胎児性抗原（CEA）に対するヒトモノクローナル抗体の作製とその抗腫瘍効果
I. T.; K. M.; S. H.; K. M.
日本分子腫瘍マーカー研究会誌, 2002, 18(1):30 - 31 - Transient hypoxia/hypoglycemia upregulates endothelin B receptors in cultured rat astrocytes.
Shibaguchi H; Himeno A; Shigematsu K; Kataoka Y; Niwa M
Glia, Jul. 2000, 31(1):91 - 94., Refereed - Role of synaptophysin in exocytotic release of dopamine from Xenopus oocytes injected with rat brain mRNA.
Shibaguchi H; Takemura K; Kan S; Kataoka Y; Kaibara M; Saito N; Taniyama K
Cell Mol Neurobiol., Jun. 2000, 20(3):401 - 408., Refereed - The increase in angiotensin type-2 receptor mRNA level by glutamate stimulation in cultured rat cortical cells.
Makino I; Shibata K; Shibaguchi H; Niwa M; Katsuragi T; Furukawa T
Brain Res., Sep. 1998, 804(2):296 - 305., Refereed - Rat peritoneal macrophages express endothelin ET(B) but not endothelin ET(A) receptors.
Sakurai-Yamashita Y; Yamashita K; Yoshida A; Obana M; Takada K; Shibaguchi H; Shigematsu K; Niwa M; Taniyama K
Eur J Pharmacol., Nov. 1997, 338(2):199 - 203., Refereed - Nitric oxide participates in the stimulatory and neurotoxic action of endothelin on rat striatal dopaminergic neurons.
Shibaguchi H; Kataoka Y; Koizumi S; Kohzuma M; Obana M; Himeno A; Yamashita K; Taniyama K
Cell Mol Neurobiol., Oct. 1997, 17(5):471 - 481., Refereed - Up-regulation of angiotensin type 2 receptor mRNA by angiotensin II in rat cortical cells.
Shibata K; Makino I; Shibaguchi H; Niwa M; Katsuragi T; Furukawa T
Biochem Biophys Res Commun., Oct. 1997, 239(2):633 - 637., Refereed - NMDA receptor involvement in endothelin neurotoxicity in rat striatal slices.
Kataoka Y; Koizumi S; Kohzuma M; Shibaguchi H; Shigematsu K; Niwa M; Taniyama K
Eur J Pharmacol., Feb. 1995, 273(3):285 - 289., Refereed - ETB receptor involvement in stimulatory and neurotoxic action of endothelin on dopamine neurones.
Kohzuma M; Kataoka Y; Koizumi S; Shibaguchi H; Nakashima MN; Yamashita K; Niwa M; Taniyama K
Neuroreport, Dec. 1994, 5(18):2653 - 2656., Refereed - Endothelin-3 stimulates inositol 1,4,5-trisphosphate production and Ca2+ influx to produce biphasic dopamine release from rat striatal slices.
Kataoka Y; Koizumi S; Niwa M; Shibaguchi H; Shigematsu K; Kudo Y; Taniyama K
Cell Mol Neurobiol., Jun. 1994, 14(3):271 - 280., Refereed - 清儒李穆堂
石田 和夫
日本中国学会報, 1989, 41:183 - 197, Refereed
- 低出力超音波を用いた非侵襲的がん超音波力学療法に用いる新規超音波感受性製剤の開発
芝口浩智
A-STEP技術移転シーズ紹介集, 2013 - がん転移抑制剤の探索を指向したがん転移モデルの構築
芝口浩智
新学術領域研究：がん研究分野の特性等を踏まえた支援活動：平成23年度研究報告集録, 2013 - 超音波のがん治療への応用
芝口浩智; 山下祐一
Research, 2011, 16(1):20 - 22 - 癌胎児性抗原に特異的なヒト抗体遺伝子を用いた複合的がん免疫療法の強化に関する研究
芝口浩智; 遠藤日富美
Research, 2010, 15(2):36 - 38 - 腫瘍細胞傷害活性増強のための新規ヒト抗体IgGサブクラス変換
芝口浩智
Research, 2006, 11(3):15 - 16 - ヒト抗体／TCR・融合遺伝子によるT細胞の腫瘍ターゲッティング（2002-2004年の研究概要）
芝口浩智
Research, 2004, 9(4):2004 - がん特異的なキメラ受容体による免疫細胞の腫瘍標的
芝口浩智; 黒木政秀
Research, 2003, 8(4):16 - 17
- モデル・コア・カリキュラム対応 医用生化学 ー生体物質の代謝と異常ー ２０１7年版
安永 晋一郎; 黒木 政秀; 黒木 求; 瀬川 波子; 衣笠 哲史; 芝口 浩智; 白須 直人; 四元 房典, Editor, 編著
福岡大学医学部生化学講座, 31 Mar. 2017
9784990942601 - モデル・コア・カリキュラム対応 医用生化学 ー生体物質の代謝と異常ー ２０１６年版
安永 晋一郎; 黒木 政秀; 黒木 求; 瀬川 波子; 衣笠 哲史; 芝口 浩智; 白須 直人; 四元 房典, Editor, 編著
福岡大学医学部生化学講座, 31 Mar. 2016
9784990314699 - モデル・コア・カリキュラム対応 医用生化学 ー生体物質の代謝と異常ー ２０１５年版
安永 晋一郎; 黒木 政秀; 黒木 求; 瀬川 波子; 衣笠 哲史; 芝口 浩智; 白須 直人; 四元 房典, Joint work, 編著
福岡大学医学部生化学講座, 31 Mar. 2015
9784990314682 - モデル・コア・カリキュラム対応 医用生化学―生体物質の代謝と異常― 2014年版
KUROKI Masahide; KUROKI Motomu; SEGAWA Namiko; SHIBAGUCHI Hirotomo; SHIRASU Naoto; YOTSUMOTO Fusanori, Editor
福岡大学医学部生化学教室, 2014
9784990314675 - Reactive oxygen species in non-invasive cancer therapy.
Hirotomo Shibaguchi, Others, chapter 9
Nova Science Publishers, Inc., 2014
9781629480497 - モデル・コア・カリキュラム対応 医用生化学―生体物質の代謝と異常― 2013年版
黒木政秀; 瀬川波子; 芝口浩智; 四元房典; 白須直人, Editor
福岡大学医学部生化学教室, 2013
9784990314668 - Targeting strategies by coupling of adenovirus vector and antibody for cancer gene therapy.
Tanaka T; Hamada H; Kuroki M; Kato K; Kinugasa T; Shibaguchi H; Kuroki M, Joint work, 319-326
Transworld Research Network, 2007 - Potentiation by protein kinase C activation of GABA release from Xenopus oocytes injected with rat brain mRNA.
Contributor, 123-7
GABA: Receptors, Transporters and Metabolism, 1996
- Development of a novel method for predicting drug-induced allergy before and after drug administration
SHIBAGUCHI Hirotomo; YASUTAKA Yuki
第45回日本免疫学会学術集会, 07 Dec. 2016, 日本免疫学会 - 薬剤アレルギー同定試験cell migration assayにおける遊走細胞に関する検討
安高勇気; 芝口浩智; 今給黎 修; 鷲山厚司; 二神幸次郎
日本薬学会第136年会, 27 Mar. 2016 - 肝障害疑いにてアレルギー誘発薬剤の同定試験を行った1症例
安高勇気; 芝口浩智; 今給黎 修; 鷲山厚司; 二神幸次郎
第25回日本医療薬学会年会, 22 Nov. 2015 - 薬剤アレルギー新規検査方法の有用性評価
安高勇気; 芝口浩智; 今給黎 修; 二神幸次郎
第31回日本薬学会九州支部大会, 07 Dec. 2014 - A rapid method for predicting drug-induced allergy using patient's serum
Shibaguchi H; Yasutaka Y; Kuroki Ma
第43回日本免疫学会学術集会, Dec. 2014 - 迅速アレルギー診断法の検討と応用
安高勇気; 芝口浩智; 今給黎 修; 二神幸次郎
第24回日本医療薬学会年会, 28 Sep. 2014 - CEAを標的とした抗腫瘍光免疫療法.
SHIRASU Naoto; SHIBAGUCHI Hirotomo; KUROKI Motomu; KUROKI Masahide
第18回日本がん免疫学会総会, Jul. 2014 - アレルギー誘発薬剤の同定試験における細胞動態解析
安高勇気; 芝口浩智; 二神幸次郎
日本薬学会第134年会, 30 Mar. 2014 - 薬物アレルギーの起因薬同定法に関する検討 -患者血清を用いたJurkat細胞の動態解析-
安高勇気; 芝口浩智; 二神幸次郎
第30回日本薬学会九州支部大会, 08 Dec. 2013 - 薬剤アレルギー患者の血清中サイトカインプロファイル
山本雄一朗; 安高勇気; 芝口浩智; 二神幸次郎
第30回日本薬学会九州支部大会, 08 Dec. 2013 - 担癌マウスモデルにおける近赤外光線免疫療法の抗腫瘍効果．
白須直人; 山田博美; 芝口浩智; 黒木 求; 黒木政秀
第17回バイオ治療法研究会学術集会, Dec. 2013 - The novel screening method of drug-induced allergy by kinetic analysis with Jurkat cells and patients' serum.
Shibaguchi, H; Yuki, Y; Kuroki, Ma
第42回日本免疫学会学術集会, Dec. 2013 - Versatile photoimmunotherapy of cancer using avidin-conjugated near infrared photosensitizer and biotinylated antibody.
Shirasu, N; Yamada, H; Shibaguchi, H; Kuroki, Mo; Kuroki, Ma
第72回日本癌学会学術総会, Oct. 2013 - 薬剤アレルギー同定法LMTの効率化に関する基礎的検討
安高勇気; 芝口浩智; 二神幸次郎
日本薬学会第133年会, 29 Mar. 2013
- International Society for Neurochemistry
- Japanese Association of Cancer Immunology (Society for Fundamental Cancer Immunology)
- The Japanese Pharmacological Society
- Japanese Society for Immunology
- The Japanese Cancer Association
- 9764029, Tumor proliferation inhibitor containing ultrasound-sensitive substrate and method for inhibiting tumor proliferation by using tumor proliferation inhibitor and low-intensity pulsed ultrasound waves
Hirotomo Shibaguchi - 6108570, 迅速アレルギー検査方法
芝口浩智, 安高勇気, 二神幸次郎 - 5908839, 超音波感受性物質を含む腫瘍増殖抑制剤及び腫瘍増殖抑制剤と低出力超音波を用いた腫瘍増殖抑制方法
芝口浩智, 水流弘文
