Hesperidin blocks varenicline-aggravated atherosclerotic plaque formation in apolipoprotein E knockout mice by downregulating net uptake of oxidized low-density lipoprotein in macrophages.
Journal of Pharmacological Sciences, Jun. 2020

Varenicline aggravates atherosclerotic plaque formation in nicotine-pretreated ApoE knockout mice due to enhanced oxLDL uptake by macrophages through downregulation of ABCA1 and ABCG1 expression.
Journal of Pharmacological Sciences, Jan. 2020

Moxifloxacin exacerbates aortic aneurysm and aortic dissection by weakening the aortic media.
The 95th Annual Meeting of the Japanese Pharmacological Society, 08 Mar. 2022

Nalmefene, a reducing alcohol consumption drug, enhanced oxLDL uptake in macrophages and aggravates atherosclerotic plaque formation in apolipoprotein E knockout mice.
The 95th Annual Meeting of the Japanese Pharmacological Society, 08 Mar. 2022

モキシフロキサシンによる大動脈瘤・解離における分化型血管平滑筋細胞マーカー発現減少
第74回日本薬理学会西南部会, 20 Nov. 2021

モキシフロキサシンによるオステオポンチンを介した大動脈瘤・解離の増悪作用
The 94th Annual Meeting of the Japanese Pharmacological Society, 08 Mar. 2021

モキシフロキサシンによるマクロファージのオステオポンチン発現増加を介した大動脈瘤・解離のリスク上昇
The 93th Annual Meeting of the Japanese Pharmacological Society, 17 Mar. 2020

バレニクリンは、a7 nAChRを介して肺胞マクロファージにおけるosteopontinの発現を減少させる
The 92th Annual Meeting of the Japanese Pharmacological Society, Mar. 2019

フルオロキノロン系抗菌薬による大動脈瘤悪化・解離におけるsmooth muscle 22αの発現変動
生体機能と創薬シンポジウム2018, Aug. 2018

動脈硬化症におけるDragon-Neogenin分子機構
生体機能と創薬シンポジウム2018, Aug. 2018

禁煙補助薬バレニクリンによるマクロファージのoxLDL取り込み促進作用
生体機能と創薬シンポジウム2018, Aug. 2018

Smoking cessation drug, varenicline, inhibited alveolar expansion in mice intratracheally administrated porcine pancreatic elastase
18th World Congress of basic and clinical pharmacology, Jul. 2018