A machine learning model of microscopic agglutination test for diagnosis of leptospirosis
Yuji Oyamada; Ryo Ozuru; Toshiyuki Masuzawa; Satoshi Miyahara; Yasuhiko Nikaido; Fumiko Obata; Mitsumasa Saito; Sharon Yvette Angelina M. Villanueva; Jun Fujii
PLOS ONE, 16 Nov. 2021, 16(11):e0259907 - e0259907, Refereed
Lead

Adipose tissue is the first colonization site of Leptospira interrogans in subcutaneously infected hamsters
Ryo Ozuru; Mitsumasa Saito; Takaaki Kanemaru; Satoshi Miyahara; Sharon Y. A. M. Villanueva; Gerald L. Murray; Ben Adler; Jun Fujii; Shin-ichi Yoshida
PLOS ONE, Feb. 2017, 12(2):e0172973, Refereed
Lead

Objectification of evaluation criteria in microscopic agglutination test using deep learning.
Risa Nakano; Yuji Oyamada; Ryo Ozuru; Michinobu Yoshimura; Kenji Hiromatsu
Journal of microbiological methods, Jul. 2024, 222:106955 - 106955, Refereed
Corresponding

Insufficient anti-spike RBD IgA responses after triple vaccination with intramuscular mRNA BNT162b2 vaccine against SARS-CoV-2
Michinobu Yoshimura; Atsuhiko Sakamoto; Ryo Ozuru; Yusuke Kurihara; Ryota Itoh; Kazunari Ishii; Akinori Shimizu; Bin Chou; Yusuke Sechi; Aya Fujikane; Shigeki Nabeshima; Kenji Hiromatsu
Heliyon, Jan. 2024, Refereed

The appearance of anti-spike RBD IgG4 responses after repetitive immunization with mRNA-based COVID-19 vaccines.
Michinobu Yoshimura; Atsuhiko Sakamoto; Ryo Ozuru; Yusuke Kurihara; Ryota Itoh; Kazunari Ishii; Akinori Shimizu; Bin Chou; Shigeki Nabeshima; Kenji Hiromatsu
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 27 Nov. 2023, Refereed

Chlamydia pneumoniae Lung Infection in Mice Induces Fatty Acid-Binding Protein 4-Dependent White Adipose Tissue Pathology.
Yusuke Kurihara; Nirwana Fitriani Walenna; Kazunari Ishii; Toshinori Soejima; Bin Chou; Michinobu Yoshimura; Ryo Ozuru; Akinori Shimizu; Ryota Itoh; Masato Furuhashi; Gökhan S Hotamisligil; Kenji Hiromatsu
Journal of immunology (Baltimore, Md. : 1950), 15 Apr. 2023, 210(8):1086 - 1097, Refereed

Longitudinal Dynamics of SARS-CoV-2 IgG Antibody Responses after the Two-Dose Regimen of BNT162b2 Vaccination and the Effect of a Third Dose on Healthcare Workers in Japan
Atsuhiko Sakamoto; Michinobu Yoshimura; Ryota Itoh; Ryo Ozuru; Kazunari Ishii; Yusuke Sechi; Shigeki Nabeshima; Kenji Hiromatsu
Vaccines, May 2022, 10(6), Refereed

Light dependent synthesis of a nucleotide second messenger controls the motility of a spirochete bacterium.
Jun Xu; Nobuo Koizumi; Yusuke V Morimoto; Ryo Ozuru; Toshiyuki Masuzawa; Shuichi Nakamura
Scientific reports, 26 Apr. 2022, 12(1):6825 - 6825, Refereed

Stx2 Induces Differential Gene Expression and Disturbs Circadian Rhythm Genes in the Proximal Tubule
Fumiko Obata; Ryo Ozuru; Takahiro Tsuji; Takashi Matsuba; Jun Fujii
Toxins, 19 Jan. 2022, 14(2):69 - 69, Refereed

Investigation of Bacteria from Spoiled Bottled Salad Dressing Leading to Gas Explosion
Fumiko Obata; Hiromi Murota; Satoshi Shibata; Ryo Ozuru; Jun Fujii
Yonago Acta Medica, 2022, 65(3):207 - 214

細菌検査を自動化する レプトスピラ症の顕微鏡下凝集試験(Microscopic Agglutination Test;MAT)を例に
尾鶴 亮; 小山田 雄仁; 増澤 俊之; 宮原 敏; 二階堂 靖彦; 齋藤 光正; Villanueva Sharon Y.A.M.; 藤井 潤
日本細菌学雑誌, Feb. 2021, 76(1):89 - 89

免疫不全マウスを用いた新たな劇症型溶血性レンサ球菌感染症マウスモデルの開発(Establishment of a new Streptococcal toxic shock syndrome model using immunocompromised mice)
辻 高寛; 小幡 史子; 尾鶴 亮; 宮原 敏; 齋藤 光正; 藤井 潤
日本細菌学雑誌, Feb. 2021, 76(1):108 - 108

Rescue from Stx2-Producing E. coli-Associated Encephalopathy by Intravenous Injection of Muse Cells in NOD-SCID Mice.
Ryo Ozuru; Shohei Wakao; Takahiro Tsuji; Naoya Ohara; Takashi Matsuba; Muhammad Y Amuran; Junko Isobe; Morio Iino; Naoki Nishida; Sari Matsumoto; Kimiharu Iwadate; Noriko Konishi; Kaori Yasuda; Kosuke Tashiro; Misato Hida; Arisato Yadoiwa; Shinsuke Kato; Eijiro Yamashita; Sohkichi Matsumoto; Yoichi Kurozawa; Mari Dezawa; Jun Fujii
Molecular therapy : the journal of the American Society of Gene Therapy, 08 Jan. 2020, 28(1):100 - 118, Refereed
Lead

Inhibition of inflammatory-molecule synthesis in THP-1 cells stimulated with phorbol 12-myristate 13-acetate by brefelamide derivatives
Gaowa Bai; Takashi Matsuba; Haruhisa Kikuchi; Haorile Chagan-Yasutan; Hirotoshi Motoda; Ryo Ozuru; Osamu Yamada; Yoshiteru Oshima; Toshio Hattori
International Immunopharmacology, Oct. 2019, 75:105831 - 105831, Refereed

Inhibition of Osteopontin Synthesis in THP-1 Cells Stimulated with Phorbol 12-Myristate 13-Acetate by Brefelamide Derivatives
Gaowa Bai; Takashi Matsuba; Haruhisa Kikuchi; Hirotoshi Motoda; Ryo Ozuru; Haorile Chagan-Yasutan; Osamu Yamada; Yoshiteru Oshima; Toshio Hattori
Reprints, 03 Jan. 2019, Refereed

Synthesis of a Cleaved Form of Osteopontin by THP-1 Cells and Its Alteration by Phorbol 12-Myristate 13-Acetate and BCG Infection
Gaowa Bai; Hirotoshi Motoda; Ryo Ozuru; Haorile Chagan-Yasutan; Toshio Hattori; Takashi Matsuba
International Journal of Molecular Sciences, 31 Jan. 2018, 19(2):418 - 418, Refereed
Lead

The usefulness of semi-solid medium in the isolation of highly virulent Leptospira strains from wild rats in an urban area of Fukuoka, Japan
Mitsumasa Saito; Sharon Y. A. M. Villanueva; Toshiyuki Masuzawa; Yusuke Haraguchi; Shuhei Ita; Satoshi Miyahara; Ryo Ozuru; Takayoshi Yamaguchi; Michinobu Yoshimura; Mami Ikejiri; Natsumi Aramaki; Muhammad Yunus Amran; Lisa Tenriesa Muslich; Ken-ichiro Iida; Yasutake Yanagihara; Nina G. Gloriani; Shin-ichi Yoshida
MICROBIOLOGY AND IMMUNOLOGY, Jun. 2015, 59(6):322 - 330, Refereed

半固形コルトフ培地を用いた福岡都心部の野生ラットからの病原性レプトスピラ分離と分離株の解析(The usefulness of semi-solid medium in the isolation of Leptospira strains from wild rats in Fukuoka)
齋藤 光正; Villanueva Sharon Yvette Angelina; 増澤 俊幸; 宮原 敏; 尾鶴 亮; 山口 孝治; 吉村 芳修; 池尻 真美; 荒牧 夏美; 飯田 健一郎; 柳原 保武; 吉田 眞一
日本細菌学雑誌, Feb. 2015, 70(1):210 - 210

フィリピンで流行している五つのレプトスピラの血清型に対するワクチンの開発と評価(Development and evaluation of vaccines against 5 leptospiral serovars prevailing in the Philippines)
Villanueva Sharon Yvette Angelina; 柳原 保武; 齋藤 光正; 瀬川 孝耶; 尾鶴 亮; 池尻 真美; Gloriani Nina; 吉田 眞一
日本細菌学雑誌, Feb. 2015, 70(1):236 - 236

Comparative Analysis of Leptospira Strains Isolated from Environmental Soil and Water in the Philippines and Japan
Mitsumasa Saito; Sharon Y. A. M. Villanueva; Antara Chakraborty; Satoshi Miyahara; Takaya Segawa; Tatsuma Asoh; Ryo Ozuru; Nina G. Gloriani; Yasutake Yanagihara; Shin-ichi Yoshida
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Jan. 2013, 79(2):601 - 609, Refereed

光活性型アデニル酸シクラーゼによるレプトスピラ・コバヤシイの運動活性化
許駿; 小泉信夫; 森本雄祐; 尾鶴亮; 増澤俊幸; 中村修一
レプトスピラ・シンポジウム抄録(CD-ROM), 2022, 58th

SARS-CoV-2 m-RNAワクチン(BNT162b)の2回接種・3回接種による抗体の獲得状況とブレイクスルー感染に関する研究
坂本篤彦; 坂本篤彦; 坂本篤彦; 吉村芳修; 伊藤竜太; 石井一成; 尾鶴亮; 栗原悠介; 瀬知裕介; 藤兼亜耶; 廣松賢治; 鍋島茂樹
日本ウイルス学会学術集会プログラム・予稿集(Web), 2022, 69th

2016年、キュウリを原因とした腸管出血性大腸菌O157の集団感染
尾鶴 亮; 立石 善隆; 小西 典子; 松本 壮吉; 松葉 隆司; 藤井 潤
日本細菌学雑誌, Feb. 2018, 73(1):68 - 68

2016年、キュウリを原因とした腸管出血性大腸菌O157の集団感染
尾鶴 亮; 立石 善隆; 小西 典子; 松本 壮吉; 松葉 隆司; 藤井 潤
日本細菌学雑誌, Feb. 2018, 73(1):68 - 68

腸管出血性大腸菌感染マウスモデルおける再生医療(Muse細胞)を用いた急性脳症の治療効果(Effects of Muse cells on acute encephalopathy caused by Shiga toxin-producing E. coil infection in mice)
尾鶴 亮; 若尾 昌平; 松葉 隆司; 磯部 順子; 木全 恵子; 綿引 正則; 出澤 真理; 藤井 潤
日本細菌学雑誌, Feb. 2017, 72(1):158 - 158

レプトスピラの病原性と菌体回転運動の関わり
尾鶴亮
第171回バイオメカニクス研究会, 16 Nov. 2018

Microbiology
99 Apr. 2021
Fukuoka University

基礎感染症学実習
20 Apr. 2015
鳥取大学

Basic Infectious Diseases
20 Apr. 2016
Tottori University

Jan. 2020 - Present
The Japanese Society for Bioinformatics

Feb. 2013 - Present
JAPANESE SOCIETY FOR BACTERIOLOGY

日本レプトスピラ研究会

重症化抑制への応用を目指したレプトスピラ由来宿主脂肪分解因子の同定と機能解析
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C)
Fukuoka University
01 Apr. 2024 - 31 Mar. 2027

レプトスピラの脂肪組織定着機構を利用したレプトスピラ症新規バイオマーカーの創出
日本学術振興会, 科学研究費助成事業 若手研究, 若手研究
鳥取大学
01 Apr. 2021 - 31 Mar. 2024

レプトスピラが宿主の脂肪組織血管内に定着する分子機構の解明
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists, Grant-in-Aid for Early-Career Scientists
Tottori University
Apr. 2018 - Mar. 2021