Lysine residues are not required for proteasome-mediated proteolysis of cellular prion protein.
Takuya Nishinakagawa; Takujiro Homma; Aoi Ikeda; Mai Hazekawa; Yurie Morita; Takehiro Nakagaki; Ryuichiro Atarashi; Noriyuki Nishida; Daisuke Ishibashi
Biochemical and biophysical research communications, 10 Oct. 2024, 735:150807 - 150807, Refereed

RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation
Takuya Nishinakagawa; Mai Hazekawa; Masato Hosokawa; Daisuke Ishibashi
Molecular Medicine Reports, 02 Feb. 2023, 27(3), Refereed

Development of an Organ-Directed Exosome-Based siRNA-Carrier Derived from Autologous Serum for Lung Metastases and Testing in the B16/BL6 Spontaneous Lung Metastasis Model
Mai Hazekawa; Takuya Nishinakagawa; Masato Hosokawa; Daisuke Ishibashi
Pharmaceutics, 07 Apr. 2022, 14(4):815 - 815, Refereed

Preparation of siRNA–PLGA/Fabʹ–PLGA mixed micellar system with target cell-specific recognition
Mai Hazekawa; Takuya Nishinakagawa; Takeshi Mori; Miyako Yoshida; Takahiro Uchida; Daisuke Ishibashi
Scientific Reports, Dec. 2021, 11(1), Refereed

Hepatic glycogenolysis is determined by maternal high-calorie diet via methylation of Pygl and it is modified by oteocalcin administration in mice
Tomoyo Kawakubo-Yasukochi; Ena Yano; Soi Kimura; Takuya Nishinakagawa; Akiko Mizokami; Yoshikazu Hayashi; Yuji Hatakeyama; Kenji Ohe; Atsushi Yasukochi; Seiji Nakamura; Eijiro Jimi; Masato Hirata
Molecular Metabolism, Dec. 2021, 54:101360 - 101360, Refereed

Enhancing the anticancer efficacy of a LL-37 peptide fragment analog using peptide-linked PLGA conjugate micelles in tumor cells
Takeshi Mori; Mai Hazekawa; Miyako Yoshida; Takuya Nishinakagawa; Takahiro Uchida; Daisuke Ishibashi
International Journal of Pharmaceutics, Sep. 2021, 606:120891 - 120891, Refereed

The new application of real-time cell-monitoring analysis system to detect cellular responses in human umbilical vein endothelial to paclitaxel
Mai Hazekawa; Takuya Nishinakagawa; Tomoyo Kawakubo-Yasukochi; Manabu Nakashima
Sensors and Materials, 19 Jun. 2020, 32(6):2127 - 2137

miR-200c-3p spreads invasive capacity in human oral squamous cell carcinoma microenvironment
Tomoyo Kawakubo-Yasukochi; Masahiko Morioka; Mai Hazekawa; Atsushi Yasukochi; Takuya Nishinakagawa; Kazuhiko Ono; Shintaro Kawano; Seiji Nakamura; Manabu Nakashima
Molecular Carcinogenesis, Feb. 2020, 57(2):295 - 302, Refereed

Evaluation of IC50 levels immediately after treatment with anticancer reagents using a real‑time cell monitoring device
Mai Hazekawa; Takuya Nishinakagawa; Tomoyo Kawakubo‑Yasukochi; Manabu Nakashima
Experimental and Therapeutic Medicine, 13 Aug. 2019, Refereed

Regulation of collagen type XVII expression by miR203a-3p in oral squamous cell carcinoma cells.
Yasukochi A; Kawakubo-Yasukochi T; Morioka M; Hazekawa M; Nishinakagawa T; Ono K; Nakashima M; Nakamura S
Journal of biochemistry, Aug. 2019, 166(2):163 - 173, Refereed

Maternal folic acid depletion during early pregnancy increases sensitivity to squamous tumor formation in the offspring in mice.
Kawakubo-Yasukochi T; Morioka M; Ohe K; Yasukochi A; Ozaki Y; Hazekawa M; Nishinakagawa T; Ono K; Nakamura S; Nakashima M
Journal of developmental origins of health and disease, May 2019, :1 - 9, Refereed

Glypican-3 gene silencing for ovarian cancer using siRNA-PLGA hybrid micelles in a murine peritoneal dissemination model
Mai Hazekawa; Takuya Nishinakagawa; Tomoyo Kawakubo-Yasukochi; Manabu Nakashima
Journal of Pharmacological Sciences, Mar. 2019, 139(3):231 - 239, Refereed

miR-200c-3pによる口腔扁平上皮癌の浸潤制御機構
Kawakubo-Yasukochi Tomoyo; Morioka Masahiko; Hazekawa Mai; Nishinakagawa Takuya; Yasukochi Atsushi; Nakamura Seiji; Nakashima Manabu
Proceedings for Annual Meeting of The Japanese Pharmacological Society, 2019, 92:1-P-090

In vitro anti-inflammatory effects of the phenylbutyric acid metabolite phenylacetyl glutamine
Mai Hazekawa; Kazuhiko Ono; Takuya Nishinakagawa; Tomoyo Kawakubo-Yasukochi; Manabu Nakashima
Biological and Pharmaceutical Bulletin, 2018, 41(6):961 - 966, Refereed

Anti-inflammatory effects of water extract from bell pepper (Capsicum annuum L. var. grossum) leaves in vitro
Mai Hazekawa; Yuko Hideshima; Kazuhiko Ono; Takuya Nishinakagawa; Tomoyo Kawakubo-Yasukochi; Tomoka Takatani-Nakase; Manabu Nakashima
EXPERIMENTAL AND THERAPEUTIC MEDICINE, Nov. 2017, 14(5):4349 - 4355, Refereed

miR-200c-3p spreads invasive capacity in human oral squamous cell carcinoma microenvironment.
Mol Carcinog, 2017, 57(2):295 - 302, Refereed

Exosomes from oral squamous carcinoma cell lines, SQUU-A and SQUU-B, define the tropism of lymphatic dissemination
Masahiko Morioka; Tomoyo Kawakubo-Yasukochi; Yoshikazu Hayashi; Mai Hazekawa; Takuya Nishinakagawa; Kazuhiko Ono; Shintaro Kawano; Seiji Nakamura; Manabu Nakashima
Journal of Oral Biosciences, Nov. 2016, 58(4):180 - 184, Refereed

The SQUU-B cell line spreads its metastatic properties to nonmetastatic clone SQUU-A from the same patient through exosomes
Tomoyo Kawakubo-Yasukochi; Masahiko Morioka; Yoshikazu Hayashi; Takuya Nishinakagawa; Mai Hazekawa; Shintaro Kawano; Seiji Nakamura; Manabu Nakashima
Journal of Oral Biosciences, 01 Feb. 2016, 58(1):33 - 38, Refereed

Sodium 4-phenylbutyrate suppresses the development of dextran sulfate sodium- induced colitis in mice
Kazuhiko Ono; Satoshi Nimura; Takuya Nishinakagawa; Yuko Hideshima; Munechika Enjyoji; Kazuki Nabeshima; Manabu Nakashima
EXPERIMENTAL AND THERAPEUTIC MEDICINE, Mar. 2014, 7(3):573 - 578, Refereed

Novel monoclonal antibodies against pancreatic juice from pancreatic cancer patients and their possible application in differential diagnosis
Masato Hamabashiri; Aya Daichou; Makiko Yasumoto; Sachiko Ogasawara; Takuya Nishinakagawa; Munechika Enjoji; Kouichi Ohshima; Hirohisa Yano; Manabu Nakashima
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, Oct. 2011, 28(4):599 - 603, Refereed

Accuracy of differential diagnosis for pancreatic cancer is improved in the combination of RCAS1 and CEA measurements and cytology in pancreatic juice
Yoshiki Naito; Yoshinobu Okabe; Masakatsu Nagayama; Takuya Nishinakagawa; Tomoki Taira; Akihiko Kawahara; Satoshi Hattori; Kazuyuki Machida; Yusuke Ishida; Ryohei Kaji; Kazuhiro Mikagi; Hisafumi Kinoshita; Makiko Yasumoto; Jun Akiba; Masayoshi Kage; Manabu Nakashima; Koichi Ohshima; Hirohisa Yano
MEDICAL MOLECULAR MORPHOLOGY, Jun. 2011, 44(2):86 - 92, Refereed

Association between lipid accumulation and the cannabinoid system in Huh7 cells expressing HCV genes
Mako Toyoda; Akira Kitaoka; Kazuyuki Machida; Takuya Nishinakagawa; Ryoko Yada; Motoyuki Kohjima; Masaki Kato; Kazuhiro Kotoh; Naoya Sakamoto; Goshi Shiota; Makoto Nakamuta; Manabu Nakashima; Munechika Enjoji
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, May 2011, 27(5):619 - 624, Refereed

Analysis of cell cycle arrest and apoptosis induced by RCAS1
Takuya Nishinakagawa; Sho Fujii; Tetsuya Nozaki; Tatsuhiro Maeda; Kazuyuki Machida; Munechika Enjoji; Manabu Nakashima
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, May 2010, 25(5):717 - 722, Refereed

Therapeutic effect of bezafibrate against biliary damage: a study of phospholipid secretion via the PPAR-α-MDR3 pathway.
M. Nakamuta; T. Fujino; R. Yada; K. Yasutake; T. Yoshimoto; N. Harada; M. Yada; N. Higuchi; M. Kato; M. Kohjima; A. Taketomi; Y. Maehara; T. Nishinakagawa; K. Machida; K. Matsunaga; M. Nakashima; K. Kotoh; M. Enjoji
INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, Jan. 2010, 48(1):22 - 28, Refereed

Changes in the expression of cholesterol metabolism-associated genes in HCV-infected liver: A novel target for therapy?
Makoto Nakamuta; Ryoko Yada; Tatsuya Fujino; Masayoshi Yada; Nobito Higuchi; Masatake Tanaka; Masayuki Miyazaki; Motoyuki Kohjima; Masaki Kato; Tsuyoshi Yoshimoto; Naohiko Harada; Akinobu Taketomi; Yoshihiko Maehara; Momoko Koga; Takuya Nishinakagawa; Manabu Nakashima; Kazuhiro Kotoh; Munechika Enjoji
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, Dec. 2009, 24(6):825 - 828, Refereed

A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human α-synuclein A30P＋A53T transgenic mice.
Kazuhiko Ono; Miyuki Ikemoto; Takeshi Kawarabayashi; Masaki Ikeda; Takuya Nishinakagawa; Masato Hosokawa; Mikio Shoji; Mitsuo Takahashi; Manabu Nakashima
PARKINSONISM & RELATED DISORDERS, Nov. 2009, 15(9):649 - 654, Refereed

Clinical effectiveness of ezetimibe for a non-obese patient with nonalcoholic fatty liver disease.
Enjoji M; Tanaka M; Miyazaki M; Higuchi N; Kato M; Kotoh K; Matsunaga K; Nishinakagawa T; Machida K; Nakashima M; Nakamuta M
Am . J . Case . Rep, 2009, 10:145 - 148, Refereed

プリオンタンパク質に対するラットモノクローナル抗体の樹立
松浦早希; 立野正浩; 鈴木菜々; 西中川拓也; 細川雅人; 石橋大輔
日本薬学会年会要旨集(Web), 2024, 144th

腸骨リンパ節法を用いたプリオンタンパク質に対するラットモノクローナル抗体の作製
鈴木菜々; 立野正浩; 松浦早希; 西中川拓也; 細川雅人; 石橋大輔
日本薬学会年会要旨集(Web), 2024, 144th

K562細胞に対する機能性マウスモノクローナル抗体8-11G-7の樹立
作元亮介; 池田葵; 西中川拓也; 細川雅人; 石橋大輔
日本薬学会年会要旨集(Web), 2024, 144th

側鎖結晶性ブロック共重合体を基盤としたミセルの薬物送達キャリアへの応用
船津百加; 櫨川舞; 渡瀬大輔; 西中川拓也; 細川雅人; 八尾滋; 石橋大輔
日本薬学会年会要旨集(Web), 2024, 144th

がん細胞培養上清に含まれる細胞障害活性因子
西中川拓也; 細川雅人; 石橋大輔
日本生化学会大会(Web), 2023, 96th

がん細胞株培養上清中の細胞障害活性因子
前野史佳; 西中川拓也; 甲斐茜; 内原佑月; 細川雅人; 石橋大輔
日本薬学会年会要旨集(Web), 2023, 143rd

腫瘍関連抗原22-1-1抗原の生物学的解析
小野菜々子; 西中川拓也; 細川雅人; 石橋大輔
日本薬学会年会要旨集(Web), 2023, 143rd

RCAS1 increases cell morphological change in fibroblasts by reducing p38 phosphorylation
西中川拓也; 櫨川舞
第81回日本癌学会学術総会, 30 Sep. 2022

腫瘍関連抗原RCAS1の生物学的機能解析
西中川拓也; 櫨川舞; 細川雅人; 石橋大輔
日本薬学会第142年会, 27 Mar. 2022

Involvement of p38 signaling pathway in the RCAS1 induced cell morphological change
西中川拓也; 櫨川舞; 細川雅人; 石橋大輔
第80回日本癌学会学術総会, 30 Sep. 2021

がん細胞培養上清中に含まれる細胞障害活性因子
西中川拓也; 櫨川舞; 石橋大輔
日本薬学会第141年会, 29 Mar. 2021

Identification of cytotoxic factor contained in tumor cell line supernatants
西中川拓也; 櫨川舞; 石橋大輔
第79回日本癌学会学術総会, 03 Oct. 2020

Analysis of cytotoxic factor contained in tumor cell line supernatants
西中川拓也; 櫨川舞; 安河内友世; 中島学
第78回日本癌学会学術総会, 26 Sep. 2019

Identify of the cytotoxic factor secreted by tumor cell line
西中川 拓也; 櫨川 舞; 安河内 友世; 中島 学
第77回日本癌学会学術総会, 30 Sep. 2018

Identify the cytotoxic factor included in supernatant of tumor cell line
西中川拓也; 櫨川舞; 安河内友世; 中島学
第76回日本癌学会学術総会, 28 Sep. 2017

Identify of the cytotoxic factor secreted by tumor cell line
西中川拓也; 櫨川舞; 安河内友世; 中島学
第75回日本癌学会学術総会, 07 Oct. 2016

Purification and characterization of the cytotoxic factor secreted from cancer cell line
西中川拓也; 櫨川舞; 安河内友世; 中島学
第74回日本癌学会学術総会, 10 Oct. 2015

Purification and characterization of the cytotoxic factor secreted from cancer cell line
西中川拓也; 秀島優子; 中島学
第73回日本癌学会学術総会, 27 Sep. 2014

PBA代謝産物のマウス炎症性サイトカイン産生に対する効果
Ono Kazuhiko; KUSUDA Mariko; HIDESHIMA Yuko; NISHINAKAGAWA Takuya; ENJOJI Munechika; NAKASHIMA Manabu
薬学会第134年会, 30 Mar. 2014

Purification and characterization of the cytotoxic factor secreted by tumor cell line
NAKASHIMA Manabu
第72回日本癌学会学術総会, 15 Oct. 2013

Involvement of MAPK signaling pathway in the RCAS1 induced cell morphological change
西中川拓也; 遠城寺宗近; 中島学
第71回日本癌学会学術総会, 20 Sep. 2012

RCAS1 expression impairs F-actin stress fiber formation
西中川拓也; 遠城寺宗近; 中島学
第70回日本癌学会学術総会, 05 Oct. 2011

Analysis of apoptotic cell death induced by RCAS1
西中川拓也; 遠城寺宗近; 園田顕三; 中島学
第69回日本癌学会学術総会, 24 Sep. 2010

Analysis of apoptotic cell death induced by RCAS1
西中川拓也; 遠城寺宗近; 園田顕三; 中島学
第68回日本癌学会学術総会, 03 Oct. 2009

Analysis of apoptotic cell death induced by RCAS1
西中川拓也; 遠城寺宗近; 園田顕三; 中島学
第67回日本癌学会学術総会, 29 Oct. 2008

日本薬学会

日本がん免疫学会

日本癌学会

マイコプラズマ由来アルギニン代謝制御蛋白質を標的とした新規がん免疫療法の開発
日本学術振興会, 科学研究費助成事業 基盤研究(C), 基盤研究(C)
福岡大学
01 Apr. 2019 - 31 Mar. 2022

癌性膵液特異的抗体の認識抗原の機能解析と高感度検出法の確立
Japan Society for the Promotion of Science, Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C)
Fukuoka University
28 Apr. 2011 - 31 Mar. 2015